Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Keshuo Ding"'
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Carboxy-terminal domain small phosphatase like 2 (CTDSPL2), one of the haloacid dehalogenase phosphatases, is associated with several diseases including cancer. However, the role of CTDSPL2 and its regulatory mechanism in lung cancer remain
Externí odkaz:
https://doaj.org/article/2f84d53f91b14c41a5a2087d6a8a61e0
Autor:
Lin Ding, Hui Jiang, Qiangwei Li, Qiushuang Li, Tian-Tian Zhang, Limeng Shang, Bin Xie, Yaling Zhu, Keshuo Ding, Xuanming Shi, Tao Zhu, Yong Zhu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)
Abstract Background Ropivacaine, a local anesthetic, exhibits anti-tumor effects in various cancer types. However, its specific functions and the molecular mechanisms involved in breast cancer cell stemness remain elusive. Methods The effects of ropi
Externí odkaz:
https://doaj.org/article/400f21f852114aa99cf101782140c32e
Autor:
Lin Dong, Lin Li, Linyan Zhu, Fei Xu, Rumeng Zhang, Qiushuang Li, Yong Zhu, Zhutian Zeng, Keshuo Ding
Publikováno v:
Biomolecules & Biomedicine (2024)
There remains ongoing debate regarding the association of homologous recombination deficiency (HRD) with patient survival across various malignancies, highlighting the need for a comprehensive understanding of HRD's role in different cancer types. Ba
Externí odkaz:
https://doaj.org/article/dd5f88c391234ca48d82318a6cc86245
Autor:
Rumeng Zhang, Zhihao Wang, Huan Wang, Lin Li, Lin Dong, Lin Ding, Qiushuang Li, Linyan Zhu, Tiantian Zhang, Yong Zhu, Keshuo Ding
Publikováno v:
Biomolecules & Biomedicine (2024)
Colon cancer, thyroid cancer, and melanoma are common malignant tumors that seriously threaten human health globally. The B-Raf proto-oncogene, serine/threonine kinase (BRAF)(V600E) mutation is an important driver gene mutation in these cancer types.
Externí odkaz:
https://doaj.org/article/e9d9d51666c4414a89450f7bdf695f00
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/fa3b3c76483349bb90c878ee5d7c82f8
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 8 (2023)
Liver metastasis represents one of the most frequent malignant diseases with no effective treatment. Functional reprogramming of Kupffer cells (KCs), the largest population of hepatic macrophages, holds promise for treating liver cancer, but remains
Externí odkaz:
https://doaj.org/article/2f17c87c7d6c473d8eb97ad97405eca3
Autor:
Sheng Tan, Ming Zhang, Xinglong Shi, Keshuo Ding, Qiang Zhao, Qianying Guo, Hao Wang, Zhengsheng Wu, Yani Kang, Tao Zhu, Jielin Sun, Xiaodong Zhao
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-16 (2021)
Abstract Background Alternative polyadenylation (APA) is an important mechanism of gene expression regulation through generation of RNA isoforms with distinct 3′ termini. Increasing evidence has revealed that APA is actively involved in development
Externí odkaz:
https://doaj.org/article/d4b71afd5180497f8f9bc7e51a329bb2
Autor:
Lin Li, Long Bai, Huan Lin, Lin Dong, Rumeng Zhang, Xiao Cheng, Zexian Liu, Yi Ouyang, Keshuo Ding
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 5637-5646 (2021)
Whether tumor mutational burden (TMB) is related to improved survival outcomes or the promotion of immunotherapy in various malignant tumors remains controversial, and we lack a comprehensive understanding of TMB across cancers. Based on the data obt
Externí odkaz:
https://doaj.org/article/29b2415f4d1945859a99bedcf4b31781
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Alternative polyadenylation (APA) is an important RNA post-transcriptional process, which can generate diverse mRNA isoforms. Increasing evidence shows that APA is involved in cell self-renewal, development, immunity, and cancer. CPSF6 is one of the
Externí odkaz:
https://doaj.org/article/323f651ed2e84009a332a7baa48c448d
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Gastric cancer is one of the major malignancies with poor survival outcome. In this study, we reported that NUDT21 promoted cell proliferation, colony formation, cell migration and invasion in gastric cancer cells. The expression levels of NUDT21 wer
Externí odkaz:
https://doaj.org/article/d5ea05866a0a4e508db29fb02dfd570e