Forced randomization: the what, why, and how

Autor: Kerstine Carter, Olga Kuznetsova, Volodymyr Anisimov, Johannes Krisam, Colin Scherer, Yevgen Ryeznik, Oleksandr Sverdlov

Publikováno v: BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-22 (2024)

Abstract Background When running a randomized controlled trial (RCT), a clinical site may face a situation when an eligible trial participant is to be randomized to the treatment that is not available at the site. In this case, there are two options:

Externí odkaz: https://doaj.org/article/6409d535618d494eb89ff5cf9a7acc55

A roadmap to using randomization in clinical trials

Autor: Vance W. Berger, Louis Joseph Bour, Kerstine Carter, Jonathan J. Chipman, Colin C. Everett, Nicole Heussen, Catherine Hewitt, Ralf-Dieter Hilgers, Yuqun Abigail Luo, Jone Renteria, Yevgen Ryeznik, Oleksandr Sverdlov, Diane Uschner, for the Randomization Innovative Design Scientific Working Group

Publikováno v: BMC Medical Research Methodology, Vol 21, Iss 1, Pp 1-24 (2021)

Abstract Background Randomization is the foundation of any clinical trial involving treatment comparison. It helps mitigate selection bias, promotes similarity of treatment groups with respect to important known and unknown confounders, and contribut

Externí odkaz: https://doaj.org/article/944d0ea49c0f4280b17832e126e27c27

Seasonal variations in exacerbations and deaths in patients with COPD during the TIOSPIR® trial

Autor: Kerstine Carter, Emmanuelle Clerisme-Beaty, Peter M.A. Calverley, Robert A. Wise, Antonio Anzueto, Norbert Metzdorf

Publikováno v: International Journal of Chronic Obstructive Pulmonary Disease. 13:605-616

Background Although COPD exacerbations are known to occur more frequently in winter, there is little information on hospitalizations and cause-specific mortality. This study aimed to examine seasonal variations in mortality and exacerbations in patie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d9961e4c499d51a5883115474653ff6
https://doi.org/10.2147/copd.s148393

Differences in outcomes between GOLD groups in patients with COPD in the TIOSPIR® trial

Autor: Kerstine Carter, Peter M.A. Calverley, Daniel Dusser, Ronald Dahl, Robert A. Wise, Antonio Anzueto, Andy Fowler

Publikováno v: Dusser, D, Wise, R A, Dahl, R, Anzueto, A, Carter, K, Fowler, A & Calverley, P MA 2016, ' Differences in outcomes between GOLD groups in patients with COPD in the TIOSPIR® trial ', International Journal of Chronic Obstructive Pulmonary Disease, vol. 11, no. 1, pp. 133—145 . https://doi.org/10.2147/COPD.S97924
International Journal of Chronic Obstructive Pulmonary Disease

Daniel Dusser,1 Robert A Wise,2 Ronald Dahl,3 Antonio Anzueto,4,5 Kerstine Carter,6 Andy Fowler,7 Peter M Calverley8 1Service de Pneumologie, Hôpital Cochin, AP-HP, Université Paris Descartes, Sorbonne Paris Cité, Paris, France; 2Asthma and Allerg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c44a7227a9fde55ffaa97ffe4ec22b24
https://www.dovepress.com/differences-in-outcomes-between-gold-groups-in-patients-with-copd-in-t-peer-reviewed-article-COPD