Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Kerstin Wennhold"'
Autor:
Alexander Quaas, Julie George, Philipp Müller, Hans Anton Schlößer, Michael von Bergwelt-Baildon, Martin Thelen, Birgit Gathof, Martin Peifer, Thomas Zander, Axel M Hillmer, Christiane Bruns, Diandra Keller, Jonas Lehmann, Kerstin Wennhold, Eugen Bauer, Maria Alejandra Garcia-Marquez, Roman Thomas, Lukas Maas, Miloš Nikolić, Wolfgang Schröder, Ali M Yazbeck
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Background The individual HLA-I genotype is associated with cancer, autoimmune diseases and infections. This study elucidates the role of germline homozygosity or allelic imbalance of HLA-I loci in esophago-gastric adenocarcinoma (EGA) and determines
Externí odkaz:
https://doaj.org/article/afc5d656bb5b494e9b31c5d4b6a0c547
Autor:
Alexander Quaas, Hans Anton Schlößer, Michael von Bergwelt-Baildon, Martin Thelen, Birgit Gathof, Axel M Hillmer, Christiane Bruns, Diandra Keller, Jonas Lehmann, Kerstin Wennhold, Hendrik Weitz, Eugen Bauer, Monika Brüggemann, Michaela Kotrova, Christoph Mallmann, Seung-Hun Chon, Maria Alejandra Garcia-Marquez
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 12 (2022)
Background Specific immune response is a hallmark of cancer immunotherapy and shared tumor-associated antigens (TAAs) are important targets. Recent advances using combined cellular therapy against multiple TAAs renewed the interest in this class of a
Externí odkaz:
https://doaj.org/article/423107d49a7e4237a30cf566c4c26b59
Autor:
Martin Thelen, Kerstin Wennhold, Jonas Lehmann, Maria Garcia-Marquez, Sebastian Klein, Elena Kochen, Philipp Lohneis, Axel Lechner, Svenja Wagener-Ryczek, Patrick Sven Plum, Oscar Velazquez Camacho, David Pfister, Fabian Dörr, Matthias Heldwein, Khosro Hekmat, Dirk Beutner, Jens Peter Klussmann, Fabinshy Thangarajah, Dominik Ratiu, Wolfram Malter, Sabine Merkelbach-Bruse, Christiane Josephine Bruns, Alexander Quaas, Michael von Bergwelt-Baildon, Hans A. Schlößer
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-12 (2021)
Abstract The immune response against cancer is orchestrated by various parameters and site-dependent specificities have been poorly investigated. In our analyses of ten different cancer types, we describe elevated infiltration by regulatory T cells a
Externí odkaz:
https://doaj.org/article/4edee7d56ead4b1585567524e79d56a7
Autor:
Axel Lechner, Hans A. Schlößer, Martin Thelen, Kerstin Wennhold, Sacha I. Rothschild, Ramona Gilles, Alexander Quaas, Oliver G. Siefer, Christian U. Huebbers, Engin Cukuroglu, Jonathan Göke, Axel Hillmer, Birgit Gathof, Moritz F. Meyer, Jens P. Klussmann, Alexander Shimabukuro-Vornhagen, Sebastian Theurich, Dirk Beutner, Michael von Bergwelt-Baildon
Publikováno v:
OncoImmunology, Vol 8, Iss 3 (2019)
B lymphocytes are important players in immune responses to cancer. However, their composition and function in head and neck squamous cell carcinoma (HNSCC) has not been well described. Here, we analyzed B cell subsets in HNSCC (n = 38), non-cancerous
Externí odkaz:
https://doaj.org/article/d4690aeed7074fd6ace42666837bf690
Autor:
Hans A. Schlößer, Martin Thelen, Axel Lechner, Kerstin Wennhold, Maria A. Garcia-Marquez, Sacha I. Rothschild, Elena Staib, Thomas Zander, Dirk Beutner, Birgit Gathof, Ramona Gilles, Engin Cukuroglu, Jonathan Göke, Alexander Shimabukuro-Vornhagen, Uta Drebber, Alexander Quaas, Christiane J. Bruns, Arnulf H. Hölscher, Michael S. Von Bergwelt-Baildon
Publikováno v:
OncoImmunology, Vol 8, Iss 1 (2019)
Tumor-infiltrating lymphocytes (TILs) are correlated to prognosis of several kinds of cancer. Most studies focused on T cells, while the role of tumor-associated B cells (TABs) has only recently gained more attention. TABs contain subpopulations with
Externí odkaz:
https://doaj.org/article/e69b1c2d74cb4a0a80fe04831ecf924e
Autor:
Hans A. Schlößer, Michael von Bergwelt-Baildon, Alexander Quaas, Christiane Bruns, Heike Löser, Sebastian Eidt, Fabinshy Thangarajah, Florian Klein, Meryem S. Ercanoglu, Alexander Shimabukuro-Vornhagen, Axel Lechner, Maria Garcia-Marquez, Ella Preugszat, Simon Schran, Jonas Lehmann, Martin Thelen, Kerstin Wennhold
Supplementary Figure 2: Gating strategy for flow cytometry. Live CD45+ cells were gated after live/dead discrimination and removal of doublets as shown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bcc0bbdc6fc5f17e8e5fc966cec0130
https://doi.org/10.1158/2326-6066.22543135
https://doi.org/10.1158/2326-6066.22543135
Autor:
Hans A. Schlößer, Michael von Bergwelt-Baildon, Alexander Quaas, Christiane Bruns, Heike Löser, Sebastian Eidt, Fabinshy Thangarajah, Florian Klein, Meryem S. Ercanoglu, Alexander Shimabukuro-Vornhagen, Axel Lechner, Maria Garcia-Marquez, Ella Preugszat, Simon Schran, Jonas Lehmann, Martin Thelen, Kerstin Wennhold
The role of B cells in antitumor immunity and their impact on emerging immunotherapies is increasingly gaining attention. B-cell effector functions include not only secretion of antibodies, but also presentation of antigens to T cells. A physiologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::373e4279b4d6f93869addbf817ed962d
https://doi.org/10.1158/2326-6066.c.6550150.v1
https://doi.org/10.1158/2326-6066.c.6550150.v1
Autor:
Hans A. Schlößer, Michael von Bergwelt-Baildon, Alexander Quaas, Christiane Bruns, Heike Löser, Sebastian Eidt, Fabinshy Thangarajah, Florian Klein, Meryem S. Ercanoglu, Alexander Shimabukuro-Vornhagen, Axel Lechner, Maria Garcia-Marquez, Ella Preugszat, Simon Schran, Jonas Lehmann, Martin Thelen, Kerstin Wennhold
Detailed list of used antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9c5cb77685d4a4d001d5a71fe6090e
https://doi.org/10.1158/2326-6066.22543129.v1
https://doi.org/10.1158/2326-6066.22543129.v1
Autor:
Michael von Bergwelt-Baildon, Alexander Shimabukuro-Vornhagen, Hinrich Abken, Michael Hallek, Sebastian Theurich, Geothy Chakupurakal, Olaf Utermöhlen, Felicitas Rataj, Sebastian Kobold, Axel Lechner, Maria Garcia-Marquez, Sabrina Reuter, Natalie Haustein, Hans Anton Schlößer, Martin Thelen, Kerstin Wennhold
Fig. S1. Flow cytometry staining of KLH and TRP2-specific B cells. Fig. S2. Quality control of CD40L-matured DCs. Fig. S3. Antigen-specific CD40B cells activate specific T cells. Fig. S4. T cells of immunized mice show normal percentages of Tregs. Fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213d0ee00f61c3aaf24fb3e44ecff15d
https://doi.org/10.1158/2326-6066.22539080.v1
https://doi.org/10.1158/2326-6066.22539080.v1
Autor:
Michael von Bergwelt-Baildon, Alexander Shimabukuro-Vornhagen, Hinrich Abken, Michael Hallek, Sebastian Theurich, Geothy Chakupurakal, Olaf Utermöhlen, Felicitas Rataj, Sebastian Kobold, Axel Lechner, Maria Garcia-Marquez, Sabrina Reuter, Natalie Haustein, Hans Anton Schlößer, Martin Thelen, Kerstin Wennhold
Cancer immunotherapy by therapeutic activation of T cells has demonstrated clinical potential. Approaches include checkpoint inhibitors and chimeric antigen receptor T cells. Here, we report the development of an alternative strategy for cellular imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d7850f71b173fe159c9c6c35fdc806
https://doi.org/10.1158/2326-6066.c.6548984.v1
https://doi.org/10.1158/2326-6066.c.6548984.v1