Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Kerstin Ure"'
Autor:
Christopher S. Ward, Teng-Wei Huang, Jose A. Herrera, Rodney C. Samaco, Christopher M. McGraw, Diana E. Parra, E. Melissa Arvide, Aya Ito-Ishida, Xiangling Meng, Kerstin Ure, Huda Y. Zoghbi, Jeffrey L. Neul
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Rett Syndrome (RTT) is a neurodevelopmental disorder caused by loss of function of the transcriptional regulator Methyl-CpG-Binding Protein 2 (MeCP2). In addition to the characteristic loss of hand function and spoken language after the first year of
Externí odkaz:
https://doaj.org/article/068530e644a94a5095446b5ab905b4e5
Autor:
Laura A Lavery, Kerstin Ure, Ying-Wooi Wan, Chongyuan Luo, Alexander J Trostle, Wei Wang, Haijing Jin, Joanna Lopez, Jacinta Lucero, Mark A Durham, Rosa Castanon, Joseph R Nery, Zhandong Liu, Margaret Goodell, Joseph R Ecker, M Margarita Behrens, Huda Y Zoghbi
Publikováno v:
eLife, Vol 9 (2020)
Methylated cytosine is an effector of epigenetic gene regulation. In the brain, Dnmt3a is the sole ‘writer’ of atypical non-CpG methylation (mCH), and MeCP2 is the only known ‘reader’ for mCH. We asked if MeCP2 is the sole reader for Dnmt3a d
Externí odkaz:
https://doaj.org/article/b078fc09c47f4ff18e2e3557478a806d
Autor:
Kerstin Ure, Hui Lu, Wei Wang, Aya Ito-Ishida, Zhenyu Wu, Ling-jie He, Yehezkel Sztainberg, Wu Chen, Jianrong Tang, Huda Y Zoghbi
Publikováno v:
eLife, Vol 5 (2016)
The postnatal neurodevelopmental disorder Rett syndrome, caused by mutations in MECP2, produces a diverse array of symptoms, including loss of language, motor, and social skills and the development of hand stereotypies, anxiety, tremor, ataxia, respi
Externí odkaz:
https://doaj.org/article/d6aeea3afa9144a29bfb8adb4ffb6ae6
Autor:
William J. Hadden, Mazen M. Ibrahim, Kerstin Ure, Hesham Abdelbary, Mariam Taha, Adam D. M. Paish, Yun Liu, David W. Holdsworth
Publikováno v:
The Bone & Joint Journal. :9-16
Aims The aims of this study were to develop an in vivo model of periprosthetic joint infection (PJI) in cemented hip hemiarthroplasty, and to monitor infection and biofilm formation in real-time. Methods Sprague-Dawley rats underwent cemented hip hem
Autor:
Jacinta Lucero, Joseph R. Ecker, M. Margarita Behrens, Chongyuan Luo, Margaret A. Goodell, Alexander J. Trostle, Kerstin Ure, Joseph R. Nery, Huda Y. Zoghbi, Rosa Castanon, Zhandong Liu, Haijing Jin, Joanna Lopez, Ying-Wooi Wan, Wei Wang, Mark A Durham, Laura A. Lavery
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Methylated cytosine is an effector of epigenetic gene regulation. In the brain, Dnmt3a is the sole ‘writer’ of atypical non-CpG methylation (mCH), and MeCP2 is the only known ‘reader’ for mCH. We asked if MeCP2 is the sole reader for Dnmt3a d
Autor:
Alexander J. Trostle, Joseph R. Ecker, Laura A. Lavery, Wei Wang, Joseph R. Nery, Jacinta Lucero, Rosa Castanon, Zhandong Liu, Haijing Jin, Huda Y. Zoghbi, Chongyuan Luo, Ying-Wooi Wan, Margaret A. Goodell, Joanna Lopez, M. Margarita Behrens, Kerstin Ure, Mark A Durham
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a2411cb8fba6e96a9d4fdbabb5277dd
https://doi.org/10.7554/elife.52981.sa2
https://doi.org/10.7554/elife.52981.sa2
Autor:
Jacinta Lucero, Alexander J. Trostle, Laura A. Lavery, Kerstin Ure, Chongyuan Luo, Margaret A. Goodell, Joseph R. Ecker, Mark A Durham, Wei Wang, Joanna Lopez, Joseph R. Nery, Rosa Castanon, Zhandong Liu, Ying-Wooi Wan, Huda Y. Zoghbi, M. Margarita Behrens
Methylated cytosine is an effector of epigenetic gene regulation. In the mammalian brain, the DNA methyltransferase, Dnmt3a, is the sole “writer” of atypical non-CpG methylation (mCH), and methyl CpG binding protein 2 (MeCP2) is the only known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a18e9faae4693e5a218c79e8e8114f09
Autor:
Ling-jie He, Jianrong Tang, Kerstin Ure, Benjamin R. Arenkiel, Wei Wang, Xiangling Meng, Dinghui Yu, Yaling Sun, Stelios M. Smirnakis, Sara E Kee, Daoyun Ji, Ryan T. Ash, Aya Ito-Ishida, Huda Y. Zoghbi, Shuang Hao, Bin Tang, Hui Lu
Publikováno v:
Neuron. 91:739-747
Loss- and gain-of-function mutations in methyl-CpG-binding protein 2 (MECP2) underlie two distinct neurological syndromes with strikingly similar features, but the synaptic and circuit-level changes mediating these shared features are undefined. Here
Autor:
Jianrong Tang, Kerstin Ure, Akash J. Patel, Rodney C. Samaco, Shuang Hao, Huda Y. Zoghbi, Yaling Sun, Daniel J. Curry, Huifang Tao, Zhenyu Wu, Yan Gao, Bin Tang
Publikováno v:
Nature. 526:430-434
Deep brain stimulation (DBS) has improved the prospects for many individuals with diseases affecting motor control, and recently it has shown promise for improving cognitive function as well. Several studies in individuals with Alzheimer disease and
Autor:
Wu Chen, Ling-jie He, Jianrong Tang, Kerstin Ure, Aya Ito-Ishida, Zhenyu Wu, Hui Lu, Huda Y. Zoghbi, Wei Wang, Yehezkel Sztainberg
Publikováno v:
eLife, Vol 5 (2016)
eLife
eLife
The postnatal neurodevelopmental disorder Rett syndrome, caused by mutations in MECP2, produces a diverse array of symptoms, including loss of language, motor, and social skills and the development of hand stereotypies, anxiety, tremor, ataxia, respi