Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Kerstin Thriene"'
Autor:
Rocco Bernasconi, Kerstin Thriene, Elena Romero‐Fernández, Christine Gretzmeier, Tobias Kühl, Mareike Maler, Pauline Nauroy, Svenja Kleiser, Anne‐Catherine Rühl‐Muth, Michael Stumpe, Dimitra Kiritsi, Stefan F Martin, Boris Hinz, Leena Bruckner‐Tuderman, Jörn Dengjel, Alexander Nyström
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 10, Pp 1-20 (2021)
Abstract Recessive dystrophic epidermolysis bullosa (RDEB), a genetic skin blistering disease, is a paradigmatic condition of tissue fragility‐driven multi‐organ fibrosis. Here, longitudinal analyses of the tissue proteome through the course of n
Externí odkaz:
https://doaj.org/article/58ca17e552d24643b054c0c4e1209d7e
Autor:
Katharina Joechle, Huda Jumaa, Kerstin Thriene, Claus Hellerbrand, Birte Kulemann, Stefan Fichtner-Feigl, Sven A. Lang, Jessica Guenzle
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
Cholangiocarcinoma (CCA) is a rare but highly aggressive tumor entity for which systemic therapies only showed limited efficacy so far. As OSI-027—a dual kinase inhibitor targeting both mTOR complexes, mTORC1 and mTORC2 - showed improved anti-cance
Externí odkaz:
https://doaj.org/article/48299dcc90324eb395cc177ebe8665e2
Publikováno v:
Foods, Vol 11, Iss 22, p 3673 (2022)
Prebiotic inulin consumption provides health benefits to the host and has also been associated with a reduction in hunger cravings. We conducted a pilot crossover study to investigate the feasibility of a juice fasting intervention with and without i
Externí odkaz:
https://doaj.org/article/9718060a621d4d9880cef5b3baea2ec0
Publikováno v:
Fermentation, Vol 8, Iss 3, p 118 (2022)
The interest in fermented food products has been increasing in recent years. Details about their microbial composition and the effects of their consumption on the human gut microbiome are of particular interest. However, evidence regarding their pote
Externí odkaz:
https://doaj.org/article/f1d7e4ff50e34bde98a6fa4b6f5c1e88
Autor:
Alexander Nyström, Kerstin Thriene, Venugopal Mittapalli, Johannes S Kern, Dimitra Kiritsi, Jörn Dengjel, Leena Bruckner‐Tuderman
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 9, Pp 1211-1228 (2015)
Abstract Genetic loss of collagen VII causes recessive dystrophic epidermolysis bullosa (RDEB)—a severe skin fragility disorder associated with lifelong blistering and disabling progressive soft tissue fibrosis. Causative therapies for this complex
Externí odkaz:
https://doaj.org/article/50329a6de9564221867a393e89929e27
Autor:
Heike Nowag, Bruno Guhl, Kerstin Thriene, Susana Romao, Urs Ziegler, Joern Dengjel, Christian Münz
Publikováno v:
EBioMedicine, Vol 1, Iss 2, Pp 116-125 (2014)
Epstein Barr virus (EBV) persists as a latent herpes virus infection in the majority of the adult human population. The virus can reactivate from this latent infection into lytic replication for virus particle production. Here, we report that autopha
Externí odkaz:
https://doaj.org/article/d0439267b0d549e2b6b54cee21180136
Autor:
Varun K Gupta, Ulrike Pech, Anuradha Bhukel, Andreas Fulterer, Anatoli Ender, Stephan F Mauermann, Till F M Andlauer, Emmanuel Antwi-Adjei, Christine Beuschel, Kerstin Thriene, Marta Maglione, Christine Quentin, René Bushow, Martin Schwärzel, Thorsten Mielke, Frank Madeo, Joern Dengjel, André Fiala, Stephan J Sigrist
Publikováno v:
PLoS Biology, Vol 14, Iss 9, p e1002563 (2016)
Memories are assumed to be formed by sets of synapses changing their structural or functional performance. The efficacy of forming new memories declines with advancing age, but the synaptic changes underlying age-induced memory impairment remain poor
Externí odkaz:
https://doaj.org/article/258b1454b30b4c2090d081b3e0a8f353
Autor:
Karin Michels, Kerstin Thriene
Publikováno v:
International Journal of Environmental Research and Public Health. 20:1463
The role of the gut microbiota in human health and disease has garnered heightened attention over the past decade. A thorough understanding of microbial variation over the life course and possible ways to influence and optimize the microbial pattern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c9cd82f95577be4b087a588bf546ba6
https://doi.org/10.3390/ijerph20021463
https://doi.org/10.3390/ijerph20021463
Publikováno v:
Curr Dev Nutr
OBJECTIVES: The effects of fermented foods on the gut microbiome are of great interest, yet evidence regarding its potential to increase gut microbial diversity, a measure likely associated with health, is lacking. Therefore, we analyzed the microbia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac9aea7aeb316d9c3325dda71c742319
https://europepmc.org/articles/PMC8181673/
https://europepmc.org/articles/PMC8181673/
Publikováno v:
Curr Dev Nutr
OBJECTIVES: Caloric restriction has been associated with beneficial effects on metabolic diseases such as type 2 diabetes, cardiovascular diseases, and cancer but the mechanisms are diverse and not fully understood. Interactions between the human hos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51787efc25e152f04234a368f6fcc033
https://doi.org/10.1093/cdn/nzab054_041
https://doi.org/10.1093/cdn/nzab054_041