Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kerstin Thol"'
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-16 (2022)
Abstract Cancer development is an evolutionary process. A key selection pressure is exerted by therapy, one of the few players in cancer evolution that can be controlled. As such, an understanding of how treatment acts to sculpt the tumour and its mi
Externí odkaz:
https://doaj.org/article/2b0afa506c4d46b3a376ebc5cbd3d3e4
Autor:
Paula Cunnea, Edward W. Curry, Elizabeth L. Christie, Katherine Nixon, Chun Hei Kwok, Ahwan Pandey, Ratri Wulandari, Kerstin Thol, Jennifer Ploski, Cristina Morera-Albert, Stephen McQuaid, Jingky Lozano-Kuehne, James J. Clark, Jonathan Krell, Euan A. Stronach, Iain A. McNeish, David D.L. Bowtell, Christina Fotopoulou
Limited evidence exists on the impact of spatial and temporal heterogeneity of high-grade serous ovarian cancer (HGSOC) on tumor evolution, clinical outcomes, and surgical operability. We perform systematic multi-site tumor mapping at presentation an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32db0edd6d3e730d4cc771fa803b5e7e
http://hdl.handle.net/10044/1/104492
http://hdl.handle.net/10044/1/104492
Autor:
Emilia Peuhu, Guillaume Jacquemet, Colinda L.G.J. Scheele, Aleksi Isomursu, Marie-Catherine Laisne, Leena M. Koskinen, Ilkka Paatero, Kerstin Thol, Maria Georgiadou, Camilo Guzmán, Satu Koskinen, Asta Laiho, Laura L. Elo, Pia Boström, Pauliina Hartiala, Jacco van Rheenen, Johanna Ivaska
Publikováno v:
Developmental cell. 57(20)
Ductal carcinoma in situ (DCIS) is a pre-invasive stage of breast cancer. During invasion, the encapsulating DCIS basement membrane (BM) is compromised, and tumor cells invade the surrounding stroma. The mechanisms that regulate functional epithelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d0deba0dd9ae8b0f798ec45adc89ed
https://pubmed.ncbi.nlm.nih.gov/36283390
https://pubmed.ncbi.nlm.nih.gov/36283390
Autor:
Emilia Peuhu, Guillaume Jacquemet, Colinda Scheel, Aleksi Isomursu, Ilkka Paatero, Kerstin Thol, Maria Georgiadou, Camilo Guzman, Satu Koskinen, Asta Laiho, Laura Elo, Pia Boström, Pauliina Hartiala, Jacco van Rheenen, Johanna Ivaska
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d595246e703184489a781a39c575a180
https://doi.org/10.2139/ssrn.4059526
https://doi.org/10.2139/ssrn.4059526
Autor:
Pia Rantakari, Saila Kauhanen, Erika Hoppela, Mervi Laukka, Kerstin Thol, Heidi Gerke, Pirjo Merilahti, Kaisa Auvinen, Pauliina Hartiala, Jemiina Salo, Marko Salmi, Emilia Peuhu, Katri Orte, Tove J. Grönroos
Publikováno v:
Journal of Gastrointestinal Surgery
Background Adhesion formation contributes to postoperative complications in abdominal and gynaecological surgery. Thus far, the prevention and treatment strategies have focused on mechanical barriers in solid and liquid form, but these methods are no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::365e3eafb8aefa34e76737b819431946
https://doi.org/10.1007/s11605-019-04425-4
https://doi.org/10.1007/s11605-019-04425-4
Autor:
Kerstin Thol, Nicholas McGranahan
Publikováno v:
Trends in Cancer. 7:175-177
Neoantigens derived from frameshift mutations in microsatellite unstable tumours are more commonly shared between different patients' cancers compared with neoantigens arising from missense mutations. A recent study by Roudko et al. evaluates the imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f547ae46a119353a24dc4c98990db63
https://doi.org/10.1016/j.trecan.2021.01.002
https://doi.org/10.1016/j.trecan.2021.01.002
Autor:
Pia Boström, Camilo Guzmán, Jacco van Rheenen, Colinda L.G.J. Scheele, Laura L. Elo, Satu Koskinen, Maria Georgiadou, Pauliina Hartiala, Ilkka Paatero, Emilia Peuhu, Asta Laiho, Guillaume Jacquemet, Kerstin Thol, Johanna Ivaska, Aleksi Isomursu
Ductal carcinoma in situ (DCIS) is a pre-invasive stage of breast cancer, where the tumor is encapsulated by a basement membrane (BM). At the invasive phase, the BM barrier is compromised enabling tumor cells to escape into the surrounding stroma. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb022fa3f1143a17f12f0442439ed675
https://doi.org/10.1101/2021.10.22.464987
https://doi.org/10.1101/2021.10.22.464987
Autor:
Kerstin Thol, Oriol Pich, Michelle Dietzen, Alice Maguire, Maria Litovchenko, Chris Bailey, Robert Bentham, Crispin Hiley, Nicholas McGranahan
Publikováno v:
Lung Cancer. 165:S56
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b5fcbaa67cd58bffd499ae7adc684ee
https://doi.org/10.1016/s0169-5002(22)00166-0
https://doi.org/10.1016/s0169-5002(22)00166-0
Autor:
Kerstin Thol, Ratri Wulandari, Christina Fotopoulou, Elizabeth L. Christie, Jennifer Ploski, Chun Hei Kwok, Katherine Nixon, David D.L. Bowtell, Edward Curry, Iain A. McNeish, Paula Cunnea
Publikováno v:
Clinical Cancer Research. 26:A10-A10
High-grade serous ovarian cancer (HGSOC) is the most common subtype of ovarian cancer, accounting for more than 70% of all epithelial ovarian cancers. It is characterized by high degrees of genomic instability and heterogeneity, with the majority of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4a1a8ae291fd5330c7a58c7d49b47f8
https://doi.org/10.1158/1557-3265.ovca19-a10
https://doi.org/10.1158/1557-3265.ovca19-a10