Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Kerstin Thim"'
Effect of an MMP-9/MMP-12 inhibitor on smoke-induced emphysema and airway remodelling in guinea pigs
Publikováno v:
Thorax. 62(8)
Background: Matrix metalloproteases (MMPs) are believed to be important in the pathogenesis of cigarette smoke-induced emphysema, but this hypothesis has only been proved in the mouse and its applicability to other species, particularly humans, is un
Autor:
Martin R. Stämpfli, Naila Svitacheva, Kerstin Thim, Maria Lindahl, John D. Taylor, Per Ola Önnervik, Amir Smailagic, Robert Virtala
Publikováno v:
Inflammation Research
Objective The aim was to create pathological changes in mice relevant to human smoke exposure that can be used to further understand the mechanisms and pathology of smoke-induced inflammatory disease. Methods Mice were exposed to tobacco smoke or lip