Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kerstin Schirrmann"'
Autor:
Anja Patricia Ramme, Leopold Koenig, Tobias Hasenberg, Christine Schwenk, Corinna Magauer, Daniel Faust, Alexandra K Lorenz, Anna-Catharina Krebs, Christopher Drewell, Kerstin Schirrmann, Alexandra Vladetic, Grace-Chiaen Lin, Stephan Pabinger, Winfried Neuhaus, Frederic Bois, Roland Lauster, Uwe Marx, Eva-Maria Dehne
Publikováno v:
Future Science OA, Vol 5, Iss 8 (2019)
Microphysiological systems play a pivotal role in progressing toward a global paradigm shift in drug development. Here, we designed a four-organ-chip interconnecting miniaturized human intestine, liver, brain and kidney equivalents. All four organ mo
Externí odkaz:
https://doaj.org/article/8b4907e94de7419ea2fc0f71c05acb8f
Autor:
Qi Zhou, Kerstin Schirrmann, Eleanor Doman, Qi Chen, Naval Singh, P. Ravi Selvaganapathy, Miguel O. Bernabeu, Oliver E. Jensen, Anne Juel, Igor L. Chernyavsky, Timm Krüger
Publikováno v:
Zhou, Q, Schirrmann, K, Doman, E, Chen, Q, Singh, N, Selvaganapathy, P R, Bernabeu, M O, Jensen, O E, Juel, A, Chernyavsky, I L & Krüger, T 2022, ' Red blood cell dynamics in extravascular biological tissues modelled as canonical disordered porous media ', Interface Focus, vol. 12, no. 6, 20220037 . https://doi.org/10.1098/rsfs.2022.0037
The dynamics of blood flow in the smallest vessels and passages of the human body, where the cellular character of blood becomes prominent, plays a dominant role in the transport and exchange of solutes. Recent studies have revealed that the micro-ha
We report observations of the self-assembly of coated droplets into regular clusters at the sudden expansion of a microfluidic channel. A double emulsion consisting of a regular train of coated microdroplets was created upstream of the channel expans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be82c715e0e89fec4b5df6bbd57cf601
Publikováno v:
71th Annual Meeting of the APS Division of Fluid Dynamics - Gallery of Fluid Motion.
Autor:
Anja Patricia Ramme, Uwe Marx, Alexandra Vladetic, Grace-Chiaen Lin, Christine Schwenk, Roland Lauster, Kerstin Schirrmann, Leopold Koenig, Christopher Drewell, Anna-Catharina Krebs, Winfried Neuhaus, Stephan Pabinger, Tobias Hasenberg, Corinna Magauer, Eva-Maria Dehne, Frédéric Y. Bois, Alexandra Lorenz, Daniel Faust
Microphysiological systems are fundamental for progressing towards a global paradigm shift in drug development through the generation of patient-on-a-chip models. An increasing number of single- and multi-organ systems have been adopted by the pharma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e43bce61eea3cc72e40489784072de53
https://doi.org/10.1101/376970
https://doi.org/10.1101/376970
Autor:
Kerstin Schirrmann, Marian Raschke, Uwe Marx, Alexandra Lorenz, Juliane Hübner, Sarah Gräßle, Tobias Hasenberg, Roland Lauster, Thomas Steger-Hartmann, Susanne Schnurre, Isabel Rütschle, Ilka Maschmeyer
Publikováno v:
Hübner, J, Raschke, M, Rütschle, I, Gräßle, S, Hasenberg, T, Schirrmann, K, Lorenz, A, Schnurre, S, Lauster, R, Maschmeyer, I, Steger-Hartmann, T & Marx, U 2018, ' Simultaneous evaluation of anti-EGFR-induced tumour and adverse skin effects in a microfluidic human 3D co-culture model ', Scientific Reports, vol. 8, no. 1, pp. 15010 . https://doi.org/10.1038/s41598-018-33462-3
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Antibody therapies targeting the epithelial growth factor receptor (EGFR) are being increasingly applied in cancer therapy. However, increased tumour containment correlates proportionally with the severity of well-known adverse events in skin. The pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd832de174861c9935521d080ffc3303
https://www.research.manchester.ac.uk/portal/en/publications/simultaneous-evaluation-of-antiegfrinduced-tumour-and-adverse-skin-effects-in-a-microfluidic-human-3d-coculture-model(f75273f7-e8ab-4945-81f0-aa9a72b7f31f).html
https://www.research.manchester.ac.uk/portal/en/publications/simultaneous-evaluation-of-antiegfrinduced-tumour-and-adverse-skin-effects-in-a-microfluidic-human-3d-coculture-model(f75273f7-e8ab-4945-81f0-aa9a72b7f31f).html
Autor:
Ulrich Kertzscher, Sven Meissner, Maria Gaertner, Lars Kirsten, Christian Schnabel, Edmund Koch, Kerstin Schirrmann
Publikováno v:
Scopus-Elsevier
In the course of pulmonary research, understanding alveolar tissue dynamics plays a critical role in the treatment of patients suffering from acute lung diseases. As a gold standard technique for monitoring micro scale changes of lung tissue, real-ti
Publikováno v:
Notes on Numerical Fluid Mechanics and Multidisciplinary Design ISBN: 9783642203251
Depending on the applied ventilation strategy, mechanical ventilation leads to alveolar epithelial and capillary endothelial damage. Protective ventilatory approaches try to minimize this biotrauma while still ensuring sufficient gas exchange. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21ec96eac03261d79dd4082786d6722f
https://doi.org/10.1007/978-3-642-20326-8_3
https://doi.org/10.1007/978-3-642-20326-8_3
Autor:
Arthur S. Slutsky, Ulrich Kertzscher, Alexander Krueger, Kerstin Schirrmann, Wolfgang M. Kuebler, Michael Mertens, Edmund Koch, Sven Meissner, Arata Tabuchi, Axel R. Pries
Publikováno v:
Critical care medicine. 37(9)
To analyze alveolar dynamics in healthy and acid-injured lungs of ventilated mice. Protective ventilation is potentially lifesaving in patients with acute lung injury. However, optimization of ventilation strategies is hampered by an incomplete under
Publikováno v:
Journal of biomechanics. 43(6)
Alveolar recruitment is a central strategy in the ventilation of patients with acute lung injury and other lung diseases associated with alveolar collapse and atelectasis. However, biomechanical insights into the opening and collapse of individual al