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Autor:
Marina Schmälzlein, Christian Heinlein, Konrad Sandhoff, Jose Nelson Lombana Sanchez, Markus Hessefort, Irene Boos, Bernadette Breiden, Christian Schulz, Clemens Steegborn, Lukas Perkams, Kerstin Ross, Manuel Mönnich, Christopher Günther Franz Graf, Carlo Unverzagt, Markus Püttner, Michael Weyand, Günter Schwarzmann
Publikováno v:
Angewandte Chemie. 129:5336-5341
The main glycoforms of the hydrophobic lysosomal glycoprotein saposin D (SapD) were synthesized by native chemical ligation. An approach for the challenging solid-phase synthesis of the fragments was developed. Three SapD glycoforms were obtained fol