Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Kerstin Renner"'
Autor:
Kerstin Renner, Tobias Schwittay, Sophia Chaabane, Johanna Gottschling, Christine Müller, Charlotte Tiefenböck, Jan-Niklas Salewski, Frederike Winter, Simone Buchtler, Saidou Balam, Maximilian V. Malfertheiner, Matthias Lubnow, Dirk Lunz, Bernhard Graf, Florian Hitzenbichler, Frank Hanses, Hendrik Poeck, Marina Kreutz, Evelyn Orsó, Ralph Burkhardt, Tanja Niedermair, Christoph Brochhausen, André Gessner, Bernd Salzberger, Matthias Mack
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Perturbed T cell responses and disturbed cytokine secretion have been shown during SARS-CoV2 infection in patients. Here the authors show reduced polyclonal T cell activity in COVID-19 patients that is caused by plasma factors and linked to poor prog
Externí odkaz:
https://doaj.org/article/c371d2526a5d4d4fbe8ed4cc2103dcb3
Autor:
Saidou Balam, Simone Buchtler, Frederike Winter, Kathrin Schmidbauer, Sophia Neumayer, Yvonne Talke, Kerstin Renner, Edward K. Geissler, Matthias Mack
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Fibrosis is a prominent feature of chronic allograft rejection, caused by an excessive production of matrix proteins, including collagen-1. Several cell types produce collagen-1, including mesenchymal fibroblasts and cells of hematopoietic origin. He
Externí odkaz:
https://doaj.org/article/085ad2c854004ce8a666eb0723e2921f
Autor:
Jonas Abel, Annika J. Walter, Vivian Glück, Clara L. Magnus, Thomas Glück, Philipp Schuster, Stefan Blaas, Ida Montanari, Michael Koller, Arno Mohr, Thilo Hinterberger, Bernd Salzberger, Kerstin Renner, Matthias Mack, Robert Bals, Tina Schmidt, Verena Klemis, Martina Sester, Romina Kardashi, Katja de With, Thomas H. Loew, Maximilian Malfertheiner, Michael Pfeifer, André Gessner, Barbara Schmidt, Daniel Schmalenberger, David Peterhoff
Recently, unexpectedly high virus-specific IgG4 levels were reported after more than two mRNA vaccinations. Class switch towards IgG4 occurs after long-term antigen exposure, downregulates immune responses and is associated with several autoimmune di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79bb6287130c957fbecb71704a0df1b7
https://doi.org/10.1101/2023.03.01.530454
https://doi.org/10.1101/2023.03.01.530454
Autor:
Kerstin Renner, Sophia Neumayer, Yvonne Talke, Simone Buchtler, Kathrin Schmidbauer, Falk Nimmerjahn, Anja Lux, Frederike Winter, Jan‐Nicklas Salewski, Matthias Mack
Publikováno v:
European Journal of Immunology. 52:656-668
B cells play a major role in the pathogenesis of many autoimmune diseases like MS, rheumatoid arthritis, or systemic lupus erythematosus. Depletion of B cells with anti-CD20 antibodies is an established therapy for MS. However, total B-cell depletion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8fec8ebe8da08f4f5be7bebcb61b495
https://doi.org/10.1002/eji.202149523
https://doi.org/10.1002/eji.202149523
Autor:
Dirk Lunz, Charlotte Tiefenböck, Jan-Niklas Salewski, Christine Müller, Evelyn Orsó, Maximilian V. Malfertheiner, Matthias Lubnow, Tobias Schwittay, Kerstin Renner, Tanja Niedermair, Florian Hitzenbichler, Christoph Brochhausen, Saidou Balam, Bernhard M. Graf, Bernd Salzberger, Marina Kreutz, André Gessner, Frederike Winter, Frank Hanses, Hendrik Poeck, Simone Buchtler, Matthias Mack, Ralph Burkhardt, Johanna Gottschling, Sophia Chaabane
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications
Nature Communications
Coronavirus disease 2019 (COVID-19) can lead to pneumonia and hyperinflammation. Here we show a sensitive method to measure polyclonal T cell activation by downstream effects on responder cells like basophils, plasmacytoid dendritic cells, monocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b685a2080ff2465cd916a1ad2596d82
https://doaj.org/article/c371d2526a5d4d4fbe8ed4cc2103dcb3
https://doaj.org/article/c371d2526a5d4d4fbe8ed4cc2103dcb3
Autor:
Kerstin Renner, Yoshinori Yamanishi, Edward K. Geissler, Dagmar Halbritter, Jan-Niklas Salewski, Saidou Balam, Hajime Karasuyama, Yvonne Talke, Kathrin Schmidbauer, Matthias Mack, Sophia Neumayer, Gabriela Schiechl-Brachner, Simone Buchtler, Frederike Winter
Publikováno v:
The Journal of Immunology. 202:3514-3523
Chronic rejection is a major problem in transplantation medicine, largely resistant to therapy, and poorly understood. We have shown previously that basophil-derived IL-4 contributes to fibrosis and vasculopathy in a model of heart transplantation wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b147f65f781308d709b4df481d7a373b
https://doi.org/10.4049/jimmunol.1801269
https://doi.org/10.4049/jimmunol.1801269
Autor:
Dirk Lunz, Niedermair T, Tiefenboeck C, Kerstin Renner, Florian Hitzenbichler, Matthias Mack, Hendrik Poeck, Frank Hanses, Frederike Winter, Maximilian V. Malfertheiner, C. Brochhausen, Ralph Burkhardt, Simone Buchtler, Evelyn Orsó, Bernd Salzberger, Marina Kreutz, André Gessner, Jan-Niklas Salewski, Matthias Lubnow, Mueller C, Bernhard M. Graf
Coronavirus disease 2019 (COVID-19) can lead to severe pneumonia and hyperinflammation. So far, insufficient or excessive T cell responses were described in patients. We applied novel approaches to analyze T cell reactivity and showed that T anergy i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::887a1b883bcfd16bfcfba098eef2d17f
https://doi.org/10.21203/rs.3.rs-76318/v1
https://doi.org/10.21203/rs.3.rs-76318/v1
Autor:
Yvonne Talke, Simone Buchtler, Hayo Castrop, Stefanie Hofmarksrichter, Alexandra Grill, Kerstin Renner, Barbara M. Klinkhammer, Kathrin Schmidbauer, Sophia Neumayer, Alexander Medvinsky, Gabriela Schiechl-Brachner, Manuel Rodriguez Gomez, Petra Stöckert, Peter Boor, Matthias Mack
Publikováno v:
Journal of the American Society of Nephrology. 29:1859-1873
Background Interstitial fibrosis is associated with chronic renal failure. In addition to fibroblasts, bone marrow–derived cells and tubular epithelial cells have the capacity to produce collagen. However, the amount of collagen produced by each of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c1a11b248107e3116279847d396345
https://doi.org/10.1681/asn.2018020138
https://doi.org/10.1681/asn.2018020138
Autor:
Anne-Mieke Metzger, Kerstin Renner, Dagmar Halbritter, Yvonne Talke, Sophia Neumayer, Sophia Metz, Simone Buchtler, Kathrin Schmidbauer, Matthias Mack
Publikováno v:
Cellular immunology. 334
A large number of animal models revealed that IL-3 plays an important role for the development of T and B cell-mediated autoimmune diseases. However, little is known about the expression and regulation of IL-3 receptors in human T and B cells and how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e97b63432847a17dc29da5b9814915
https://pubmed.ncbi.nlm.nih.gov/30274838
https://pubmed.ncbi.nlm.nih.gov/30274838
Autor:
Fabian Hermann, Gabriela Schiechl, Manuel Rodriguez Gomez, Matthias Mack, Yvonne Talke, Hilke Brühl, Jens Schlossmann, Hans-Joachim Anders, Kerstin Renner, Kathrin Schmidbauer
Publikováno v:
Kidney International. 88:1088-1098
MRL/lpr mice develop a spontaneous autoimmune disease that closely resembles human systemic lupus erythematosus (SLE) with DNA autoantibodies, hypergammaglobulinemia, immune complex glomerulonephritis, and systemic vasculitis. Little is known about t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1691aedc8932737b4c5f69420eb425b3
https://doi.org/10.1038/ki.2015.196
https://doi.org/10.1038/ki.2015.196