Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Kerstin Reim"'
Autor:
Uwe Thorsten Lux, Jutta Meyer, Olaf Jahn, Adam Davison, Norbert Babai, Andreas Gießl, Anna Wartenberg, Heinrich Sticht, Nils Brose, Kerstin Reim, Johann Helmut Brandstätter
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Adaptation of photoreceptor sensitivity to varying light intensities is a fundamental requirement for retinal function and vision. Adaptive mechanisms in signal transduction are well described, but little is known about the mechanisms that adapt the
Externí odkaz:
https://doaj.org/article/35cce0d7cb9b4c9d81e3effc86a79b21
Autor:
Asha Kiran Akula, Xin Zhang, Julio S. Viotti, Dennis Nestvogel, Jeong-Seop Rhee, Rene Ebrecht, Kerstin Reim, Fred Wouters, Thomas Liepold, Olaf Jahn, Ivan Bogeski, Thomas Dresbach
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Neurotransmitter release is mediated by an evolutionarily conserved machinery. The synaptic vesicle (SV) associated protein Mover/TPRGL/SVAP30 does not occur in all species and all synapses. Little is known about its molecular properties and how it m
Externí odkaz:
https://doaj.org/article/bd88b6e42d3c4ddf8e9a60044d777648
Autor:
Uwe Thorsten Lux, Johanna Ehrenberg, Anneka Joachimsthaler, Jenny Atorf, Bianca Pircher, Kerstin Reim, Jan Kremers, Andreas Gießl, Johann Helmut Brandstätter
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 8131 (2021)
Complexins (Cplxs) 1 to 4 are components of the presynaptic compartment of chemical synapses where they regulate important steps in synaptic vesicle exocytosis. In the retina, all four Cplxs are present, and while we know a lot about Cplxs 3 and 4, l
Externí odkaz:
https://doaj.org/article/a25ba281dc764053926a1335d8e52bcc
Autor:
Suna Lahut, Suzana Gispert, Özgür Ömür, Candan Depboylu, Kay Seidel, Jorge Antolio Domínguez-Bautista, Nadine Brehm, Hülya Tireli, Karl Hackmann, Caroline Pirkevi, Barbara Leube, Vincent Ries, Kerstin Reim, Nils Brose, Wilfred F. den Dunnen, Madrid Johnson, Zsuzsanna Wolf, Marc Schindewolf, Wiebke Schrempf, Kathrin Reetz, Peter Young, David Vadasz, Achilleas S. Frangakis, Evelin Schröck, Helmuth Steinmetz, Marina Jendrach, Udo Rüb, Ayşe Nazlı Başak, Wolfgang Oertel, Georg Auburger
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 5, Pp 619-631 (2017)
Parkinson's disease (PD) is a frequent neurodegenerative process in old age. Accumulation and aggregation of the lipid-binding SNARE complex component α-synuclein (SNCA) underlies this vulnerability and defines stages of disease progression. Determi
Externí odkaz:
https://doaj.org/article/f247356cd98c40f2b0349f1591cc83ae
Publikováno v:
Cell Reports, Vol 26, Iss 10, Pp 2521-2530.e5 (2019)
Summary: SNARE-mediated synaptic vesicle (SV) fusion is controlled by multiple regulatory proteins that determine neurotransmitter release efficiency. Complexins are essential SNARE regulators whose mode of action is unclear, as available evidence in
Externí odkaz:
https://doaj.org/article/1f732c93a36c40b89b28f4499e131a18
Autor:
Lena S. Mortensen, Silvia J.H. Park, Jiang-bin Ke, Benjamin H. Cooper, Lei Zhang, Cordelia Imig, Siegrid Löwel, Kerstin Reim, Nils Brose, Jonathan B. Demb, Jeong-Seop Rhee, Joshua H. Singer
Publikováno v:
Cell Reports, Vol 15, Iss 10, Pp 2239-2250 (2016)
Complexin (Cplx) proteins modulate the core SNARE complex to regulate exocytosis. To understand the contributions of Cplx to signaling in a well-characterized neural circuit, we investigated how Cplx3, a retina-specific paralog, shapes transmission a
Externí odkaz:
https://doaj.org/article/3c96857817d840289321a4eb85904210
Autor:
Uwe Thorsten Lux, Jutta Meyer, Olaf Jahn, Adam Davison, Norbert Babai, Andreas Gießl, Anna Wartenberg, Heinrich Sticht, Nils Brose, Kerstin Reim, Johann Helmut Brandstätter
Publikováno v:
SSRN Electronic Journal.
Autor:
Johanna Ehrenberg, Johann Helmut Brandstätter, Bianca Pircher, Anneka Joachimsthaler, Jan Kremers, Uwe Thorsten Lux, Kerstin Reim, Jenny Atorf, Andreas Gießl
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 22; Issue 15; Pages: 8131
International Journal of Molecular Sciences, Vol 22, Iss 8131, p 8131 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 15; Pages: 8131
International Journal of Molecular Sciences, Vol 22, Iss 8131, p 8131 (2021)
Complexins (Cplxs) 1 to 4 are components of the presynaptic compartment of chemical synapses where they regulate important steps in synaptic vesicle exocytosis. In the retina, all four Cplxs are present, and while we know a lot about Cplxs 3 and 4, l
Autor:
Divya Sachidanandan, Steffen Altrichter, Nadine Ehmann, Kerstin Reim, Nicole Scholz, Cordelia Imig, Robert J. Kittel, Olaf Jahn, Jutta Meyer, Marius Lamberty, Manfred Heckmann, Martin Pauli, Nils Brose, Benjamin H. Cooper, Anne Bormann, Stefan Hallermann, Christian Stigloher, Tobias Langenhan
Publikováno v:
The Journal of Cell Biology
By performing an in vivo screen in Drosophila melanogaster, Scholz, Ehmann, et al. identify Complexin as a functional interaction partner of Bruchpilot. The two proteins mediate a physical attachment of synaptic vesicles to the active zone cytomatrix
Publikováno v:
Cell Reports
Cell Reports, Vol 26, Iss 10, Pp 2521-2530.e5 (2019)
Cell Reports, Vol 26, Iss 10, Pp 2521-2530.e5 (2019)
Summary: SNARE-mediated synaptic vesicle (SV) fusion is controlled by multiple regulatory proteins that determine neurotransmitter release efficiency. Complexins are essential SNARE regulators whose mode of action is unclear, as available evidence in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::207b33d365f51eeb71caa71b58483a7e
http://hdl.handle.net/2445/196447
http://hdl.handle.net/2445/196447