Altered hypothalamic protein expression in a rat model of Huntington's disease.

Autor: Wei-na Cong, Huan Cai, Rui Wang, Caitlin M Daimon, Stuart Maudsley, Kerstin Raber, Fabio Canneva, Stephan von Hörsten, Bronwen Martin

Publikováno v: PLoS ONE, Vol 7, Iss 10, p e47240 (2012)

Huntington's disease (HD) is a neurodegenerative disorder, which is characterized by progressive motor impairment and cognitive alterations. Changes in energy metabolism, neuroendocrine function, body weight, euglycemia, appetite function, and circad

Externí odkaz: https://doaj.org/article/17a865b49aac4ad5a0751487a9b7e5a9

Early postnatal behavioral, cellular, and molecular changes in models of Huntington disease are reversible by HDAC inhibition

Autor: Andreas Bauer, Alexander P. Osmand, Yvonne K. Urbach, Rachel Y. Cheong, Bhavana Gupta, Kerstin Raber, Rainer Kuhn, Anja Schulze-Krebs, Alexander Andreew, Florian A. Siebzehnrubl, Ines Blockx, Saliha Moussaoui, Claus Zabel, Johanna Habermeyer, Per Svenningsson, Martin Paucar, Ludwig Aigner, Andreas Weiss, Huu Phuc Nguyen, Fabio Canneva, Sandra Moceri, Laurent Roybon, Annemie Van der Linden, Michael Bonin, Sebastien Couillard-Despres, Olaf Riess, Dennis A. Steindler, Michael Stephan, Åsa Petersén, Stephan von Hörsten, Dalila Achoui

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America 115(37), E8765-E8774 (2018). doi:10.1073/pnas.1807962115
Proceedings of the National Academy of Sciences of the United States of America

Huntington disease (HD) is an autosomal dominant neurodegenerative disorder caused by expanded CAG repeats in the huntingtin gene (HIT). Although mutant HTT is expressed during embryonic development and throughout life, clinical HD usually manifests

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3729c290198bceffa1f542f426584a80
https://pubmed.ncbi.nlm.nih.gov/30206321

Reduced airway inflammation in CD26/DPP4-deficient F344 rats is associated with altered recruitment patterns of regulatory T cells and expression of pulmonary surfactant proteins

Autor: Reinhard Pabst, J Krainski, Andreas Schmiedl, S. von Hörsten, Kerstin Raber, F. Schwichtenhövel, K Zscheppang, Jutta Schade, Christian Klemann, Dirk Wedekind, Michael Stephan, Thomas Glaab, T Beekmann, C Acevedo

Publikováno v: Clinical & Experimental Allergy. 40:1794-1808

Introduction CD26 is highly expressed on lung epithelial cells as well as on immune cells. Ovalbumin (OVA)-induced airway inflammation induces a further increase of CD26 expression. CD26-deficient rat strains exhibit blunted clinical courses in model

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3bd89eeaf44788c5b685b10ab6559fc9
https://doi.org/10.1111/j.1365-2222.2010.03547.x

Automated phenotyping and advanced data mining exemplified in rats transgenic for Huntington's disease

Autor: Johan Kullingsjö, Stephan von Hörsten, Fabio Canneva, Yvonne K. Urbach, Huu Phuc Nguyen, Theresa Andreasson, Kerstin Raber, Olaf Riess, Henrik Ponten, Anne-C. Plank

Publikováno v: Journal of neuroscience methods. 234

Background The need for improving throughput, validity, and reliability in the behavioral characterization of rodents may benefit from integrating automated intra-home-cage-screening systems allowing the simultaneous detection of multiple behavioral

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6514ce8bd03e5c0bbdfd64db5ec1a26
https://pubmed.ncbi.nlm.nih.gov/25020253

Correction: Altered Hypothalamic Protein Expression in a Rat Model of Huntington's Disease

Autor: Kerstin Raber, Caitlin M. Daimon, Huan Cai, Wei-na Cong, Fabio Canneva, Bronwen Martin, Stephan von Hörsten, Rui Wang, Stuart Maudsley

Publikováno v: PLoS ONE, Vol 7, Iss 11 (2012)
PLoS ONE

There was an error in the Funding statement. The statement should read: This work was supported by the Intramural Program of the National Institute on Aging, National Institutes of Health.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac913369f273a55cfaf75dc182ff6129
http://europepmc.org/articles/PMC3552740