Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kerstin Mock"'
Autor:
Waltraut Lehmann, Dirk Mossmann, Julia Kleemann, Kerstin Mock, Chris Meisinger, Tilman Brummer, Ricarda Herr, Simone Brabletz, Marc P. Stemmler, Thomas Brabletz
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
The transcription factors ZEB1 and YAP function in different pathways yet both activate aggressive behaviour in cancer cells. Here, the authors describe that the proteins physically interact and that this changes the transcriptional activity of ZEB1
Externí odkaz:
https://doaj.org/article/c28d750a3a21475fbd801e7e361107d4
Autor:
Thomas Brabletz, Vignesh Sundararajan, Simone Brabletz, Karolina Bajdak, Marc P. Stemmler, Ulrich T. Hopt, Jochen Maurer, Tilman Brummer, Bogdan-Tiberius Preca, Jessica Pfannstiel, Ulrich F. Wellner, Kerstin Mock
Publikováno v:
International Journal of Cancer. 137:2566-2577
Invasion and metastasis of carcinomas are often activated by induction of aberrant epithelial-mesenchymal transition (EMT). This is mainly driven by the transcription factor ZEB1, promoting tumor-initiating capacity correlated with increased expressi
Autor:
Marc P. Stemmler, Maria Berthold, Zoran Culig, Simone Meidhof, Manuel Ruh, Simone Brabletz, Kerstin Mock, Martin Puhr, Waltraut Lehmann, Bogdan-Tiberius Preca, Thomas Brabletz, Ulrich F. Wellner, Anika Weber, Ulrich T. Hopt, Simon Küsters, Peter Bronsert, Michael Lübbert, Tobias Keck, Ulrike Burk, Julia Schüler
Publikováno v:
EMBO Molecular Medicine
Therapy resistance is a major clinical problem in cancer medicine and crucial for disease relapse and progression. Therefore, the clinical need to overcome it, particularly for aggressive tumors such as pancreatic cancer, is very high. Aberrant activ
Autor:
Thomas Brabletz, Marc P. Stemmler, Jochen Maurer, Vignesh Sundararajan, Waltraut Lehmann, Peter Bronsert, Alexandra Matzge-Ogi, Simone Brabletz, Kerstin Mock, Véronique Orian-Rousseau, Bogdan-Tiberius Preca, Karolina Bajdak
Publikováno v:
Oncotarget
// Bogdan-Tiberius Preca 1, 2, 3 , Karolina Bajdak 1 , Kerstin Mock 1 , Waltraut Lehmann 1 , Vignesh Sundararajan 1 , Peter Bronsert 2, 4, 5 , Alexandra Matzge-Ogi 6, 7 , Veronique Orian-Rousseau 6 , Simone Brabletz 8 , Thomas Brabletz 8 , Jochen Mau
Autor:
Dirk Mossmann, Chris Meisinger, Simone Brabletz, Ricarda Herr, Waltraut Lehmann, Tilman Brummer, Thomas Brabletz, Marc P. Stemmler, Kerstin Mock, Julia Kleemann
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Early dissemination, metastasis and therapy resistance are central hallmarks of aggressive cancer types and the leading cause of cancer-associated deaths. The EMT-inducing transcriptional repressor ZEB1 is a crucial stimulator of these processes, par
Autor:
Bogdan-Tiberius, Preca, Karolina, Bajdak, Kerstin, Mock, Vignesh, Sundararajan, Jessica, Pfannstiel, Jochen, Maurer, Ulrich, Wellner, Ulrich T, Hopt, Tilman, Brummer, Simone, Brabletz, Thomas, Brabletz, Marc P, Stemmler
Publikováno v:
International journal of cancer. 137(11)
Invasion and metastasis of carcinomas are often activated by induction of aberrant epithelial-mesenchymal transition (EMT). This is mainly driven by the transcription factor ZEB1, promoting tumor-initiating capacity correlated with increased expressi
Autor:
Norbert Hilf, Michael Weichel, Ivica Fucek, Martin Treder, Uwe Reusch, Dominik Maurer, Vera Molkenthin, Oliver Schoor, Erich Rajkovic, Carsten Reinhardt, Kristina Ellwanger, Kerstin Mock, Toni Weinschenk, Michael Tesar, Sebastian Bunk, Dominik Hinz
Publikováno v:
Cancer Research. 77:3753-3753
Tumor-associated antigens for effective and safe T-cell engagement are very limited, leaving a need to open up the therapeutic target space. Targeting disease-specific MHC/peptide complexes with bispecific T-cell-recruiting antibodies is a highly att
Autor:
Marc P. Stemmler, Kerstin Mock, Tilman Brummer, Bogdan-Tiberius Preca, Thomas Brabletz, Simone Brabletz
Publikováno v:
Oncotarget
Tumor cell invasion, dissemination and metastasis is triggered by an aberrant activation of epithelial-to-mesenchymal transition (EMT), often mediated by the transcription factor ZEB1. Disseminating tumor cells must acquire specific features that all
Publikováno v:
The Journal of Biological Chemistry
Background: Regulation of cell adhesion is important for embryonic development and to prevent cancer metastasis. Results: Zeb1 controls cell adhesion in zebrafish embryos and human cancer cell lines through transcriptional repression of E-cadherin, E