Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Kerstin Maaser"'
Autor:
C. Hanski, W. Hopfenmüller, Martin Zeitz, Hubert J. Stein, Patricia Grabowski, I. Sturm, Peter T. Daniel, Hans Scherübl, Kerstin Maaser
Publikováno v:
Zeitschrift für Gastroenterologie. 41
Autor:
Kerstin Maaser, Andreas P. Sutter, Detlef Schuppan, Michael Höpfner, Hans Scherübl, Alexander Huether
Publikováno v:
Journal of Hepatology. 43:808-816
Background/Aims Hepatocellular carcinoma (HCC) is the fifth most common cause of cancer deaths worldwide. Inhibitors of cholesterol biosynthesis (‘statins') have been proposed as promising adjunctive anticancer agents to treat HCC, but their mode o
Autor:
Martin Zeitz, Isrid Sturm, Patricia Grabowski, Heinz-Johannes Buhr, Kerstin Maaser, Peter T. Daniel, Katharina Schelwies, Bernd Dörken, Hans Scherübl
Publikováno v:
International Journal of Colorectal Disease. 21:221-230
Neuroendocrine differentiation is an independent prognostic factor in colorectal cancer. Moreover, an altered p53/BAX pathway is associated with a poor clinical outcome in Union Internationale Contre le Cancer (UICC) stage III disease. Because these
Autor:
Werner Hopfenmüller, Martin Zeitz, Christoph Hanski, Bernd Dörken, Hans Scherübl, Harald Stein, Patricia Grabowski, Isrid Sturm, Heinz-Johannes Buhr, Kerstin Maaser
Publikováno v:
Oncology Research and Treatment. 28:399-403
Recently, we have analyzed new prognostic markers in colorectal cancer including neuroendocrine differentiation, overexpression of the sialyl-Lex antigen, overexpression of the peripheral benzodiazepine receptor (PBR), BAX protein expression and p53
Autor:
Rajan Somasundaram, Michael Höpfner, Detlef Schuppan, Bernhard Heine, Kerstin Maaser, Harald Stein, Martin Zeitz, Antje Krahn, Gesine Bradacs, Hans Scherübl, Kirsten Vormbrock, Patricia Grabowski, Andreas P. Sutter
Publikováno v:
Journal of Hepatology. 41:799-807
Background/Aims Hepatocellular carcinoma (HCC) is one of the most common causes of cancer deaths worldwide. Thus, novel therapies are urgently needed. A promising approach is the use of peripheral benzodiazepine receptor (PBR) ligands which inhibit t
Autor:
Patricia Grabowski, Andreas P. Sutter, Antje Krahn, Hans Scherübl, Michael Höpfner, Kerstin Maaser
Publikováno v:
Biochemical and Biophysical Research Communications. 324:878-886
Specific ligands of the peripheral benzodiazepine receptor (PBR) have been shown to induce both apoptosis and G1/G0 cell cycle arrest in colorectal cancers. The signaling pathways leading to cell cycle arrest are still unknown. Using cDNA array techn
Publikováno v:
European Journal of Cell Biology. 83:709-715
Tumor cell invasion requires coordinated cell adhesion to an extracellular matrix (ECM) substrate at the leading edge and concomitant detachment at the cell rear. Known detachment mechanisms include the slow sliding of focal contacts, the detachment
Publikováno v:
British Journal of Cancer
Specific ligands of the peripheral benzodiazepine receptor (PBR) are known to induce apoptosis and cell cycle arrest in oesophageal cancer cells. However, the underlying mechanisms are still unknown. Here, we investigated the transcriptional alterati
Autor:
H. Scherer, Hans Scherübl, Bodo Hoffmeister, B von Lampe, Bernhard Heine, Harald Stein, P Däubler, B Barthel, Kerstin Maaser
Publikováno v:
British Journal of Cancer
Patients with (previous) head and neck cancer (HNC) are at high risk for developing second squamous cell cancer of the oesophagus. The role of cyclooxygenase-2 (COX-2) in oesophageal squamous carcinogenesis has not yet been investigated in this high-
Autor:
Hans Scherübl, B Barthel, Kerstin Maaser, Pierre Carayon, Michael Höpfner, Patricia Grabowski, A P Sutter, S. Faiss, Martin Zeitz
Publikováno v:
International Journal of Cancer. 102:318-327
Esophageal cancer is the most markedly increasing tumor entity in Western countries. Due to very poor 5-year-survival, new therapeutic approaches are mandatory. Peripheral benzodiazepine receptors (PBR) have been implicated in growth control of vario