Výsledky vyhledávání - "Kerstin Lindgren"

A Novel Polypeptide Derived From Human Lactoferrin in Sodium Hyaluronate Prevents Postsurgical Adhesion Formation in the Rat

Autor: Margit Mahlapuu, Mattias Münnich, Veronika Sjöstrand, Elin Nilsson, Inger Mattsby-Baltzer, Marie-Louise Ivarsson, Kjell Olmarker, Camilla Björn, Kerstin Lindgren

Publikováno v: Annals of Surgery. 250:1021-1028

The objective of the study was to evaluate whether a peptide derived from human lactoferrin, PXL01 could act safely to reduce the formation of peritoneal adhesions in the rat model and to map the molecular mechanisms of its action.Adhesion formation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3b78012936b974d9b1fd3c43a72fe25
https://doi.org/10.1097/sla.0b013e3181b246a7

Zobrazit plný text záznamu

Regulation of the muscle-specific AMP-activated protein kinase α2β2γ3 complexes by AMP and implications of the mutations in the γ3-subunit for the AMP dependence of the enzyme

Autor: Sofia Martinsson, Mårten Persson, Margit Mahlapuu, Mattias Ormestad, Kerstin Lindgren, L. Thomas Svensson

Publikováno v: FEBS Journal. 274:2887-2896

The AMP-activated protein kinase is an evolutionarily conserved heterotrimer that is important for metabolic sensing in all eukaryotes. The muscle-specific isoform of the regulatory γ-subunit of the kinase, AMP-activated protein kinase γ3, has a ke

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::31ca50a5d496597f8c5e5cc4fbfcf5c2
https://doi.org/10.1111/j.1742-4658.2007.05821.x

Zobrazit plný text záznamu

Role of ADAMTS-1 in Atherosclerosis

Autor: Tina Nilsson, Anders Thelin, Eva Hurt-Camejo, Peter Brodin, Ann-Cathrine Jönsson-Rylander, Ann-Katrin Andersson, Anette Hammarström, Chung-Hyun Lee-Søgaard, Kerstin Lindgren, Jan-Olof Andersson, Margareta Behrendt, Pia Wallbrandt, Birgitta Rosengren, Regina Fritsche-Danielson, Annika Westin

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 25:180-185

Objective— We investigated the potential role of ADAMTS-1 (a disintegrin and metalloprotease with thrombospondin motif type I) in atherogenesis. Methods and Results— ADAMTS-1 is expressed at the highest levels in the aorta when compared with othe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4ff68ed3ee4d4400a7a7497204d0117
https://doi.org/10.1161/01.atv.0000150045.27127.37

Zobrazit plný text záznamu

The 5′-AMP-activated Protein Kinase γ3 Isoform Has a Key Role in Carbohydrate and Lipid Metabolism in Glycolytic Skeletal Muscle

Autor: Göran Hjälm, Leif Andersson, Carina Johansson, Margit Mahlapuu, Tatiana L. Steiler, Valérie Amarger, Juleen R. Zierath, Brian R. Barnes, Dana Galuska, Ying Leng, Stefan L. Marklund, Mark R. Walter, Magnus Åbrink, Kerstin Lindgren, David Stapleton

Publikováno v: Journal of Biological Chemistry. 279:38441-38447

5'-AMP-activated protein kinase (AMPK) is a metabolic stress sensor present in all eukaryotes. A dominant missense mutation (R225Q) in pig PRKAG3, encoding the muscle-specific gamma3 isoform, causes a marked increase in glycogen content. To determine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c68027d281bf8a51b1a58c944804f748
https://doi.org/10.1074/jbc.m405533200

Zobrazit plný text záznamu

Increases in melanin-concentrating hormone and MCH receptor levels in the hypothalamus of dietary-obese rats

Autor: Joanne A. Harrold, Peter Brodin, Peter King, Mona Byström, Gareth Williams, Kerstin Lindgren, Kerstin Enquist, Joanne C. Elliott, Assar Bäckman

Publikováno v: Molecular Brain Research. 128:150-159

Melanin-concentrating hormone (MCH) is a hypothalamic neuropeptide that stimulates feeding and increases body weight in rodents. We studied the role of the system in energy homeostasis and its regulation by the satiety signals, leptin and insulin. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34119e1ce8a5b1eecd935fdfbc6cd77e
https://doi.org/10.1016/j.molbrainres.2004.06.010

Zobrazit plný text záznamu

Efficacy of the Novel Topical Antimicrobial Agent PXL150 in a Mouse Model of Surgical Site Infections

Autor: Margit Mahlapuu, Veronika Sjöstrand, Kerstin Lindgren, Emma Sjöström, Joakim Håkansson, Camilla Björn

Antimicrobial peptides have recently emerged as a promising new group to be evaluated in the therapeutic intervention of infectious diseases. This study evaluated the anti-infectious effect of the short, synthetic, broad-spectrum antimicrobial peptid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e08fafbe2ec6578503637c058a631c
https://europepmc.org/articles/PMC3993255/

Zobrazit plný text záznamu

Recombinant human bile salt-stimulated lipase: an example of defectiveO-glycosylation of a protein produced in milk of transgenic mice

Autor: Thore Johansson, Jan Törnell, Mats Strömqvist, Kerstin Lindgren, Anders Edlund, Lennart Lundberg, Lennart Hansson, Michael Edlund

Publikováno v: Transgenic Research. 5:475-485

The expression of recombinant human bile salt-stimulated lipase (bssl) was targeted to the lactating mammary gland of transgenic mice. Expression of recombinant genes comprising bsslcDNA, or alternatively genomic bssl DNA, under control of regulatory

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b13c7b018964268940aab3e110924281
https://doi.org/10.1007/bf01980213

Zobrazit plný text záznamu

Differences in the glycosylation of recombinant and native human milk bile salt-stimulated lipase revealed by peptide mapping

Autor: Kristina Juneblad, Lennart Hansson, Kerstin Lindgren, Mats Strömqvist

Publikováno v: Journal of Chromatography A. 718:53-58

The milk of some mammals contains a bile salt-stimulated lipase (BSSL). Human milk BSSL is heavily glycosylated (30-40% carbohydrate) and present at a concentration of approximately 100-200 mg/l, thereby being one of the most abundant human whey prot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::324e384d56f46894aa241ebcb58a3d7d
https://doi.org/10.1016/0021-9673(95)00632-x

Zobrazit plný text záznamu

Anti-infectious and anti-inflammatory effects of peptide fragments sequentially derived from the antimicrobial peptide centrocin 1 isolated from the green sea urchin, Strongylocentrotus droebachiensis

Autor: Joakim Håkansson, Klara Stensvåg, Tor Haug, Camilla Björn, Emma Myhrman, Kerstin Lindgren, Margit Mahlapuu, Hans-Matti Blencke, Veronika Sjöstrand

Publikováno v: AMB Express

Bacterial resistance against antibiotic treatment has become a major threat to public health. Antimicrobial peptides (AMPs) have emerged as promising alternative agents for treatment of infectious diseases. This study characterizes novel synthetic pe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::275b0c1dc79a63d084626079c7dbcf4e
https://doi.org/10.1186/2191-0855-2-67

Zobrazit plný text záznamu

The novel antimicrobial peptide PXL150 in the local treatment of skin and soft tissue infections

Autor: Camilla Björn, Kerstin Lindgren, Joakim Håkansson, Margit Mahlapuu, Emma Myhrman, Veronika Sjöstrand

Publikováno v: Applied Microbiology and Biotechnology

Dramatic increase in bacterial resistance towards conventional antibiotics emphasises the importance to identify novel, more potent antimicrobial therapies. Antimicrobial peptides (AMPs) have emerged as a promising new group to be evaluated in therap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac17bac22f590452fc3fb615b36e19ee
https://pubmed.ncbi.nlm.nih.gov/23053090

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání