Výsledky vyhledávání - "Kerstin Kramer"

Gene expression changes in rat liver following exposure to liver growth agents: role of Kupffer cells in xenobiotic-mediated liver growth

Autor: Nick Plant, Kathryn E. Plant, Peter G. Lord, Jon Lyon, G. Gordon Gibson, Kerstin Kramer, Sarah E Crunkhorn

Publikováno v: Biochemical Pharmacology. 67:107-118

Many xenobiotics are known to cause liver enlargement and hepatocarcinogenesis in rats, although the molecular mechanisms that underlie this effect remain largely undefined. Human exposure to several of these compounds, including glucocorticoids and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f01be3beaa1b7a5d6447ab544822057b
https://doi.org/10.1016/j.bcp.2003.09.001

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Protein expression analysis of drug-mediated hepatotoxicity in the Sprague-Dawley rat

Autor: Kerstin Kramer, Peter G. Lord, John N. Wood, Geoff Heald, Wai J. Man, Paul Cutler, Peter J. Bugelski, Ian R. White, Duncan Bryant, Patrick Camilleri

Publikováno v: PROTEOMICS. 2:1577-1585

This study has investigated the protein changes in rat liver elicited by a group of model hepatotoxicants, methapyrilene, cyproterone acetate and dexamethasone and offers a compelling argument in support of the use of two-dimensional polyacrylamide g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::78423c76bcc0f2a688d9181342ace04f
https://doi.org/10.1002/1615-9861(200211)2:11<1577::aid-prot1577>3.0.co

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Principal component analysis of mass spectra of peptides generated from the tryptic digestion of protein mixtures

Autor: William Neville, Duncan Bryant, Ian R. White, Patrick Camilleri, Wai J. Man, Soraya Monté, Kerstin Kramer, Peter Bugelski

Publikováno v: Rapid Communications in Mass Spectrometry. 15:418-427

Principal component analysis (PCA) has been used to analyse mass spectral peptide profiles obtained from the enzymatic digestion of standard protein mixtures. Scores and loadings plots clearly revealed peptide fragments that differentiated one protei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c3ada0b3e4e013999ec4428fb4e7695e
https://doi.org/10.1002/rcm.247

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Quantitative evaluation of neurons in the mucosal plexus of adult human intestines

Autor: Kerstin Kramer, Marion Raab, Samir Jabari, Michael Kressel, Alexandre B. M. da Silveira, Axel Brehmer

Publikováno v: Histochemistry and cell biology. 136(1)

The consequence of presence versus absence of mucosal neurons is not consistently assessed. Here, we addressed two questions. First, based on resected gut specimens of 65 patients/body donors suffering from different diseases, counts of mucosal neuro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df4779df97fbd6612f133f6af25ca912
https://pubmed.ncbi.nlm.nih.gov/21461752

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Summary recommendations for standardization and reporting of metabolic analyses

Publikováno v: Nature biotechnology. 23(7)

Summary recommendations for standardization and reporting of metabolic analyses : The Standard Metabolic Reporting Structures (SMRS) working group outlines its vision for an open,community-driven specification for the standardization and reporting of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ad981a4a0ab2a8b10845e1505c95f46
https://pubmed.ncbi.nlm.nih.gov/16211053

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Protein expression changes in the Sprague Dawley rat liver proteome following administration of peroxisome proliferator activated receptor alpha and gamma ligands

Autor: William Hayes, Duncan Bryant, John N. Wood, Wai J. Man, Peter J. Bugelski, Joanna D. Holbrook, Paul Cutler, Ian R. White, Patrick Camilleri, Kerstin Kramer, Peter G. Lord

Publikováno v: Proteomics. 3(4)

Peroxisome proliferator activated receptors (PPARs) are members of the nuclear receptor superfamily and are intimately involved in lipid metabolism and energy homeostasis. Activation of these receptors in rodents can lead to hepatomegaly and ultimate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88051e3de025a028f9a5fbe5fd2fb3bf
https://pubmed.ncbi.nlm.nih.gov/12687617

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