Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kerstin Kaddatz"'
Autor:
Josefine Stockert, Alexander Wolf, Kerstin Kaddatz, Evelyn Schnitzer, Florian Finkernagel, Wolfgang Meissner, Sabine Müller-Brüsselbach, Michael Kracht, Rolf Müller
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e63011 (2013)
The peroxisome proliferator-activated receptor subtypes PPARα, PPARβ/δ, PPARγ are members of the steroid hormone receptor superfamily with well-established functions in transcriptional regulation. Here, we describe an unexpected cytoplasmic funct
Externí odkaz:
https://doaj.org/article/6445710e006344f286931b2bb1cefae9
Autor:
Till Adhikary, Kerstin Kaddatz, Florian Finkernagel, Anne Schönbauer, Wolfgang Meissner, Maren Scharfe, Michael Jarek, Helmut Blöcker, Sabine Müller-Brüsselbach, Rolf Müller
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16344 (2011)
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors with essential functions in lipid, glucose and energy homeostasis, cell differentiation, inflammation and metabolic disorders, and represent important drug targets. PPARs heter
Externí odkaz:
https://doaj.org/article/4bbf80cb4acd497f8dcab065e313d310
Autor:
Kerstin Kaddatz, Sabine Müller-Brüsselbach, Florian Finkernagel, Rolf Müller, Till Adhikary, Josefine Stockert, Wolfgang Meissner
Publikováno v:
Nucleic Acids Research
Previous work has provided strong evidence for a role of peroxisome proliferator-activated receptor β/δ (PPARβ/δ) and transforming growth factor-β (TGFβ) in inflammation and tumor stroma function, raising the possibility that both signaling pat
Autor:
Sabine Müller-Brüsselbach, Till Adhikary, Kerstin Kaddatz, Wolfgang Meissner, Florian Finkernagel, Rolf Müller
Publikováno v:
Journal of Biological Chemistry. 285:29469-29479
Peroxisome proliferator-activated receptors (PPARs) not only play a key role in regulating metabolic pathways but also modulate inflammatory processes, pointing to a functional interaction between PPAR and cytokine signaling pathways. In this study,
Autor:
Alexander Wolf, Sabine Müller-Brüsselbach, Rolf Müller, Florian Finkernagel, Wolfgang Meissner, Evelyn Schnitzer, Kerstin Kaddatz, Josefine Stockert, Michael Kracht
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e63011 (2013)
PLoS ONE
PLoS ONE
The peroxisome proliferator-activated receptor subtypes PPARα, PPARβ/δ, PPARγ are members of the steroid hormone receptor superfamily with well-established functions in transcriptional regulation. Here, we describe an unexpected cytoplasmic funct
Autor:
Maren Scharfe, Sabine Müller-Brüsselbach, Sonja Lieber, Silke Reinartz, Kerstin Kaddatz, Josefine Stockert, Philipp M. Toth, Till Adhikary, Michael Jarek, Dominique T. Brandt, Florian Finkernagel, Wolfgang Meissner, Frithjof Martin Scheer, Robert Grosse, J Obert, Rolf Müller, Simone Naruhn, Wibke E. Diederich
Publikováno v:
Oncogene
Besides its established functions in intermediary metabolism and developmental processes, the nuclear receptor peroxisome proliferator-activated receptor β/δ (PPARβ/δ) has a less defined role in tumorigenesis. In the present study, we have identi
Autor:
Till Adhikary, Rolf Müller, Veronika F.S. Pape, Sabine Müller-Brüsselbach, Gerhard Klebe, Stefanie Dörr, Simone Naruhn, Kerstin Kaddatz, Philipp M. Toth, Wibke E. Diederich
Publikováno v:
Molecular pharmacology. 80(5)
Peroxisome proliferator-activated receptor β/δ (PPARβ/δ) is a ligand-regulated nuclear receptor with essential functions in metabolism and inflammation. We have synthesized a new derivative [methyl 3-(N-(4-(hexylamino)-2-methoxyphenyl)sulfamoyl)t
Autor:
Michael Jarek, Sabine Müller-Brüsselbach, Kerstin Kaddatz, Florian Finkernagel, Till Adhikary, Rolf Müller, Helmut Blöcker, Anne Schönbauer, Wolfgang Meissner, Maren Scharfe
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16344 (2011)
PLoS ONE
PLoS ONE
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors with essential functions in lipid, glucose and energy homeostasis, cell differentiation, inflammation and metabolic disorders, and represent important drug targets. PPARs heter
Autor:
Bernhard Watzer, Rolf Müller, Kerstin Kaddatz, Till Adhikary, Sabine Müller-Brüsselbach, Simone Naruhn, Thomas Klein, Wolfgang Meissner
Publikováno v:
Molecular pharmacology. 77(2)
Peroxisome proliferator-activated receptor (PPARs) modulate target gene expression in response to unsaturated fatty acid ligands, such as arachidonic acid (AA). Here, we report that the AA metabolite 15-hydroxyeicosatetraenoic acid (15-HETE) activate
Specific components of prostanoid-signaling pathways are present in non-small cell lung cancer cells
Autor:
Rolf Müller, Tanja Fauti, Mihaela Kreutzer, Kerstin Kaddatz, Andreas Neubauer, Carola Seifart, Martin Kömhoff, Horst Schweer, Sabine Müller-Brüsselbach
Publikováno v:
Europe PubMed Central
Scopus-Elsevier
Scopus-Elsevier
In the present study, we measured prostanoid synthesis and the expression of genes associated with prostanoid signaling in human non-small cell lung carcinoma (NSCLC) cell lines and in primary human tumors. Consistent with the proposed growth promoti