Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Kerstin J, Rolfe"'
Publikováno v:
Recent Patents on Regenerative Medicine. 1:164-172
Autor:
Janette Richardson, Addie Grobbelaar, C. Vigor, Claire Linge, Kerstin J. Rolfe, Laurie Montgomery Irvine
Publikováno v:
Journal of Investigative Dermatology. 127(11):2656-2667
Early human fetuses regenerate cutaneous wounds perfectly without scarring. However, transforming growth factor-beta1 (TGF-beta1), the cytokine linked with scarring in mature tissue, is also present during fetal wound repair, albeit transiently. We p
Publikováno v:
International journal of burns and trauma. 2(1)
It is estimated worldwide that over 6 million people per annum experience a burn injury. Despite advances in management and improved survival rates, the incidence of hypertrophic scarring remains high. These scars are particularly common after burns
Publikováno v:
The Journal of hand surgery, European volume. 37(6)
This study investigated the attachment of intrinsic and extrinsic, mobilized and immobilized adhesion cells to the extracellular matrix. Five New Zealand White rabbit forepaws were dissected to isolate the flexor tendon core, tendon surface and synov
Publikováno v:
Current opinion in investigational drugs (London, England : 2000). 11(11)
Abnormal wound healing is a major problem in healthcare today, with both scarring and chronic wounds affecting large numbers of individuals worldwide. Wound healing is a complex process involving several variables, including growth factors and their
Publikováno v:
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. 18(1)
Dermal fibrosis, or scarring, following surgical incisions, traumatic wounds and burns presents a major clinical burden. Transforming growth factor (TGF)-beta1 is a major factor known to stimulate fibroblast proliferation, collagen production, and th
Publikováno v:
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. 15(6)
The multipotent growth factor transforming growth factor (TGF)-beta1 is consistently linked with fibrosis and scarring. The perfect (scarless) healing of cutaneous wounds in early gestational age fetuses is proposed to be due to this tissue's predomi
Autor:
Lois J, Eva, Kerstin J, Rolfe, Allan B, MacLean, Wendy M N, Reid, Anne Christine Wong Te, Fong, Julie, Crow, Christopher W, Perrett
Publikováno v:
The Journal of reproductive medicine. 52(5)
To perform a pilot study to investigate the relationship between localized, provoked vulvodynia of the vestibule and inflammatory cytokine expression.Women with a diagnosis of localized, provoked vulvodynia had tissue samples taken for vulvar express
Autor:
Kerstin J. Rolfe, Elisabeth Clayton, Claire Linge, Bushan Hardas, Janette Richardson, C. Vigor
Publikováno v:
The Journal of investigative dermatology. 125(1)
Failure of apoptosis has been postulated to cause the hypercellularity and thus excess scar-tissue formation of hypertrophic scars (HTS). Here, we have examined the susceptibility of fibroblasts derived from normal or HTS to apoptosis induced during
Autor:
Patricia E, Ellis, Lan Fong, Wong Te Fong, Kerstin J, Rolfe, Julie C, Crow, Wendy M N, Reid, Tim, Davidson, Allan B, MacLean, Christopher W, Perret
Publikováno v:
Anticancer research. 22(2A)
Paget's disease of the vulva and the breast are uncommon conditions. The pathogenesis underlying these diseases is still unclear. Vascular endothelial growth factor-A (VEGF-A), a potent angiogenic factor, has been demonstrated in a variety of tumour