Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kerstin Hirschfelder"'
Autor:
Yunsheng Gao, Joy Birkelbach, Chengzhang Fu, Jennifer Herrmann, Herbert Irschik, Bernd Morgenstern, Kerstin Hirschfelder, Ruijuan Li, Youming Zhang, Rolf Jansen, Rolf Müller
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Myxobacteria serve as a treasure trove of secondary metabolites. During our ongoing search for bioactive natural products, a novel subclass of disorazoles termed disorazole Z was discovered. Ten disorazole Z family members were purified from
Externí odkaz:
https://doaj.org/article/a9bcc911fd694cd29d1fbf1aa2184424
Autor:
Sonja M. Kessler, Rebecca T. Hahn, Britta Diesel, Nina Hachenthal, Alexandra K. Kiemer, Jessica Hoppstädter, Hanno Huwer, Kerstin Hirschfelder
Publikováno v:
Atherosclerosis. 234(2)
Objective Glucocorticoid-induced leucine zipper (GILZ) represents an anti-inflammatory mediator, whose downregulation has been described in various inflammatory processes. Aim of our study was to decipher the regulation of GILZ in vascular inflammati
Autor:
Tolga, Eichhorn, Corinna, Hiller, Kerstin, Hirschfelder, Martin, Frank, R Luise, Krauth-Siegel, Rolf, Müller, Rolf, Mertens, Thomas, Efferth
Publikováno v:
Cancer genomicsproteomics. 10(1)
Therapies targeting p53 mostly concentrate on (re)activation of the p53 protein, to further induce apoptosis in cancer cells. In the present investigations, the focus was on the identification of small molecules that block the DNA-binding domain of p
Autor:
Kerstin Hirschfelder, Rolf Jansen, Rolf Mueller, Juergen Engel, Michael Teifel, Babette Aicher, Herbert Irschik, Eckhard Guenther, Peter Schmidt
Publikováno v:
Molecular Cancer Therapeutics. 10:C214-C214
In search of novel antitumor agents natural macrocyclic polyketides called Disorazols have been isolated from myxobacterium Sorangium cellulosum[1,2,3]. Here we show that Disorazol Z specifically produced by strain So ce427, possesses outstanding cyt