Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kerstin Freidel"'
Publikováno v:
Cardiovascular Research. 83:778-784
Aims We recently reported that prostacyclin suppresses protease-activated receptor-1 (PAR-1) in human vascular smooth muscle cells (VSMC) via cyclic AMP and protein kinase A. This study examines the downstream mechanisms, particularly the role of nuc
Publikováno v:
European Journal of Biochemistry. 224:605-611
Glucose repression in the yeast Saccharomyces cerevisiae designates a global regulatory system controlling the expression of various sets of genes required for the utilization of alternate carbon sources. In a screen, designed for the selection of mu
Autor:
Wolfgang Eberhardt, Karsten Schrör, Seema Dangwal, Jens W. Fischer, Kerstin Freidel, Anke C Rosenkranz, Anke Doller, Klaus Jobi, Bernhard H. Rauch
Publikováno v:
Free radical biologymedicine. 51(9)
Activated factor X (FXa) exerts coagulation-independent actions such as proliferation of vascular smooth muscle cells (SMCs) through the protease-activated receptors PAR-1 and PAR-2. Both receptors are upregulated upon vascular injury but the underly
Publikováno v:
Current Genetics. 20:441-448
By recessive mutations, we have identified five genes, TYE1-TYE5, that are required for Ty-mediated expression of ADH2. These tye mutations not only suppress transcription of ADH2 when associated with a Ty element but are also defective in transcript
Autor:
Bernhard H. Rauch, Klaus Schulze-Osthoff, Jens W. Fischer, Artur-Aron Weber, Kerstin Freidel, Karsten Schrör, Petra Censarek, Jan-Julius Stampfuss, Maria Grandoch, Ute Fischer, Gernot Kaber, Tilo Grosser
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 28(7)
Objectives— Apoptotic monocytes release membrane microparticles which may play a major role in thrombogenicity through a P-selectin glycoprotein ligand (PGSL-1)–mediated mechanism. We have studied systematically the regulation of PSGL-1 expressio
Publikováno v:
European journal of pharmacology. 551(1-3)
A cyclooxygenase-1 splice variant (cyclooxygenase-1b), cloned from canine brain, was proposed to be an acetaminophen-sensitive enzyme. Unlike in canines, the retention of intron 1 in the human sequence results in a frame shift and predicts a truncati
Autor:
Artur-Aron Weber, Thomas Hohlfeld, Jutta Meyer-Kirchrath, Michael Udelhoven, Sun-Jung Ku, Kerstin Freidel, Karsten Schrör, Petra Censarek
Publikováno v:
Thrombosis and haemostasis. 92(5)
SummaryThere are two principal cyclooxygenase isoforms referred to as COX-1 and COX-2. Recently, COX-3 has been identified. We have demonstrated the expression of COX-2 in platelets from patients after coronary artery bypass grafting (CABG). Careful
Autor:
Frank Schulte, E Schlüter, Cornelis P. Hollenberg, Kerstin Freidel, Jürgen J. Heinisch, Eckhard Boles, T Miosga, Friedrich K. Zimmermann
Publikováno v:
Journal of bacteriology. 179(9)
We have characterized the gene YOR347c of Saccharomyces cerevisiae and shown that it encodes a second functional pyruvate kinase isoenzyme, Pyk2p. Overexpression of the YOR347c/PYK2 gene on a multicopy vector restored growth on glucose of a yeast pyr
Growth and carbon metabolism in triosephosphate isomerase (delta tpi1) mutants of Saccharomyces cerevisiae are severely inhibited by glucose. By using this feature, we selected for secondary site revertants on glucose. We defined five complementation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f518d55a1bec4904ad3bf2b777911f
https://europepmc.org/articles/PMC206608/
https://europepmc.org/articles/PMC206608/
Publikováno v:
Molecular and General Genetics MGG. 207:421-429
We have analysed functional properties of putative proteins encoded by the yeast transposable element, Ty1, by overexpression of TY genes. High-level expression was achieved by appropriate fusion of a Ty sequence, TY9C, to the yeast ADH1 promoter and