Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Kerstin Engel"'
Autor:
Vanessa Hänchen, Stefanie Kretschmer, Christine Wolf, Kerstin Engel, Shahryar Khattak, Katrin Neumann, Min Ae Lee-Kirsch
Publikováno v:
Stem Cell Research, Vol 64, Iss , Pp 102895- (2022)
Mutations in TREX1, encoding three prime repair exonuclease 1, cause Aicardi-Goutières syndrome (AGS) 1, an autoinflammatory disease characterized by neurodegeneration and constitutive activation of the antiviral cytokine type I interferon. Here, we
Externí odkaz:
https://doaj.org/article/fcb43ec64a754d08a33bdb8b8bbe2e94
Autor:
Vanessa Hänchen, Stefanie Kretschmer, Christine Wolf, Kerstin Engel, Shahryar Khattak, Katrin Neumann, Min Ae Lee-Kirsch
Publikováno v:
Stem Cell Research, Vol 64, Iss , Pp 102912- (2022)
Mutations in SAMHD1, encoding SAM and HD domain-containing protein 1, cause Aicardi-Goutières syndrome (AGS) 5, an infancy-onset autoinflammatory disease characterized by neurodegeneration and chronic activation of type I interferon. Here, we report
Externí odkaz:
https://doaj.org/article/3586418d6aa5442a809b8b1bdae9854d
Autor:
Christine Wolf, Barbara Kind, Ee Lyn Lim, Gregor Dückers, Sarah Koss, Kerstin Engel, Eusebia Lara-Villacanas, Kathrin Siepermann, Tim Niehues, Carina C. de Oliveira Mann, Eicke Latz, Olivia Majer, Min Ae Lee-Kirsch
Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by the loss of tolerance to nuclear antigens. Activation of type I interferon (IFN) induced by immune recognition of self-nucleic acids by endosomal Toll-like receptors (TLR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96996de4989ecd5ecd8dabf04c22e49c
https://doi.org/10.21203/rs.3.rs-1877908/v1
https://doi.org/10.21203/rs.3.rs-1877908/v1
Autor:
Victoria Tüngler, Reinhard Berner, K. Ungerath, Min Ae Lee-Kirsch, Kerstin Engel, M. von der Hagen, N. König, Martin Smitka
Publikováno v:
Neuropediatrics. 48:S1-S45
Autor:
Min Ae Lee-Kirsch, Christine Wolf, Kerstin Engel, Reiner Schwenke, Claudia Günther, Franziska Schmidt, Nick Zimmermann, Anne Lüth
Importance Familial chilblain lupus is a monogenic autosomal dominant form of cutaneous lupus erythematosus that in most cases is caused by mutations in the 3 prime repair exonuclease 1 (TREX1). Familial chilblain lupus presents in early childhood wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cdebdf00c7849df94c3739ca059b5ad
https://europepmc.org/articles/PMC6440279/
https://europepmc.org/articles/PMC6440279/
Autor:
M. Cristina Cardoso, Barbara Kind, Kerstin Engel, Alexander Rapp, Christine Wolf, Min Ae Lee-Kirsch
Publikováno v:
Methods in Molecular Biology ISBN: 9781493973057
Single cell gel electrophoresis or comet assay enables the quantification of DNA damage such as single-strand or double-strand breaks on a single cell level. Here, we describe a variant of this method for the detection of ribonucleotides embedded in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b85c54522aad169da7cff0e088e192fb
https://doi.org/10.1007/978-1-4939-7306-4_21
https://doi.org/10.1007/978-1-4939-7306-4_21
Autor:
Kerstin Engel, Christine Wolf, Claudia Günther, Max Schuster, Victoria Tüngler, Christoph Fiehn, Hugo Álvarez, N. König, Osvaldo Chara, Raphaela Goldbach-Mansky, Emanuel Cura Costa, Min Ae Lee-Kirsch
Objectives Familial chilblain lupus is a monogenic form of cutaneous lupus erythematosus caused by loss-of-function mutations in the nucleases TREX1 or SAMHD1. In a family without TREX1 or SAMHD1 mutation, we sought to determine the causative gene an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59626966d8f7251586405e475fe59aa5
https://ard.bmj.com/content/76/2/468
https://ard.bmj.com/content/76/2/468
Autor:
Kerstin Engel, Tobias Kronenberg
Publikováno v:
Zeitschrift für Energiewirtschaft. 32:280-290
Dieser Beitrag untersucht den Effekt des demographischen Wandels auf den Energieverbrauch in zwei deutschen Bundeslandern, Hamburg und Mecklenburg-Vorpommern. Mikrodaten aus der Einkommens- und Verbrauchsstichprobe des Statistischen Bundesamts werden
Publikováno v:
Biodiversity and Conservation. 17:3165-3180
Effect of site history on forest plant and insect communities was studied by comparing afforestations on former agricultural land with reafforestations on ancient woodland sites. Vascular plants, mosses, true bugs, lacewings and saproxylic beetles we