Výsledky vyhledávání - "Kerstin Duning"

Akademický článek

KIBRA: a new gateway to learning and memory?

Autor: Armin Schneider, Matthew J Huentelman, Kerstin Duning, Karoly Nikolich

Publikováno v: Frontiers in Aging Neuroscience, Vol 2 (2010)

The genetic locus encoding KIBRA, a member of the WWC family of proteins, has recently been shown to be associated with human memory performance through genome-wide single nucleotide polymorphism screening. Gene expression analysis and a variety of f

Externí odkaz: https://doaj.org/article/ce675f1e75a14c9790b53048c9204658

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WW and C2 domain-containing proteins regulate hepatic cell differentiation and tumorigenesis through the hippo signaling pathway

Autor: Hermann Pavenstädt, Marius Sudol, Thomas Weide, Joachim Kremerskothen, Anke Hermann, Veerle Van Marck, Sascha Gromnitza, Dirk Oliver Wennmann, Kerstin Duning, Liliana Schaefer, Maria Edeling

Publikováno v: Hepatology (Baltimore, Md.). 67(4)

The Hippo pathway regulates cell differentiation, proliferation, and apoptosis. Upon activation, it inhibits the import of the transcriptional coactivator yes-associated protein (YAP) into the nucleus, thus suppressing transcription of pro-proliferat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ec0b7cec8a708e257d3793950c8d27
https://pubmed.ncbi.nlm.nih.gov/29116649

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Tissue-specific differences in the regulation of KIBRA gene expression involve transcription factor TCF7L2 and a complex alternative promoter system

Autor: Boris Schmitz, Michael Schelleckes, Joachim Kremerskothen, Eva Brand, Katrin Guske, Stefan-Martin Brand, Hermann Pavenstädt, Kerstin Duning

Publikováno v: Journal of Molecular Medicine. 92:185-196

KIBRA has been described as a key regulator of the Hippo signaling pathway, regulating organ size control, cell contact inhibition, cell growth, as well as tumorigenesis and cystogenesis. Since there is scarce information on KIBRA gene expression reg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a751c1d98013577ced360073fccb78fa
https://doi.org/10.1007/s00109-013-1089-y

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The memory gene KIBRA is a bidirectional regulator of synaptic and structural plasticity in the adult brain

Autor: Marco C. Frey, Mélissa Farinelli, Safa Mohanna, Fabrice Heitz, Hermann Pavenstädt, Isabelle M. Mansuy, M C Kahn, Kerstin Duning

Publikováno v: Neurobiology of learning and memory. 135

Memory formation is associated with activity-dependent changes in synaptic plasticity. The mechanisms underlying these processes are complex and involve multiple components. Recent work has implicated the protein KIBRA in human memory, but its molecu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79af27452a4c5835924a1ee0ba450dc2
https://pubmed.ncbi.nlm.nih.gov/27498008

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Polycystin-2 Activity Is Controlled by Transcriptional Coactivator with PDZ Binding Motif and PALS1-associated Tight Junction Protein

Autor: Nina Meyer, Deike Rosenbusch, Arseni Markoff, Ulf Schulze, Thomas Weide, Hermann Pavenstädt, Kerstin Duning, Yuemin Tian, Karl Kunzelmann, Marc Alexander Schlüter

Publikováno v: Journal of Biological Chemistry. 285:33584-33588

Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent monogenic cause of kidney failure, characterized by the development of renal cysts. ADPKD is caused by mutations of the polycystin-1 (PC1) or polycystin-2 (PC2) genes. PC2 enco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34404a67c6ea9c8a78829a28641e6d06
https://doi.org/10.1074/jbc.c110.146381

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Deletion of KIBRA, protein expressed in kidney and brain, increases filopodial-like long dendritic spines in neocortical and hippocampal neurons in vivo and in vitro

Autor: Anja Blanque, Kerstin Duning, Daniele Repetto, Johannes Brockhaus, Astrid Rohlmann, Hermann Pavenstädt, Ilka Wolff, Markus Missler

Publikováno v: Frontiers in Neuroanatomy
Frontiers in Neuroanatomy, Vol 9 (2015)

Spines are small protrusions arising from dendrites that receive most excitatory synaptic input in the brain. Dendritic spines represent dynamic structures that undergo activity-dependent adaptations, for example, during synaptic plasticity. Alterati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9829bdc5a04202403f7ea76b093f799
http://europepmc.org/articles/PMC4335192

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Interaction of rat poly(A)-binding protein with poly(A)- and non-poly(A) sequences is preferentially mediated by RNA recognition motifs 3 + 4

Autor: Carola Mullin, Kerstin Duning, Joachim Kremerskothen, Dietmar Richter, Evita Mohr, Angelika Barnekow

Publikováno v: FEBS Letters. 576:437-441

Vasopressin (VP) mRNA and the non-coding BC200 RNA are sorted to neuronal dendrites. Among proteins interacting specifically with both RNAs is the multifunctional poly(A)-binding protein (PABP) consisting of four RNA recognition motifs (RRMs) and a C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95ce4b2be0f2c74c3e2d9c5ccb3fe639
https://doi.org/10.1016/j.febslet.2004.09.054

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Impact of Common KIBRA allele on human cognitive function

Autor: Heike Wersching, Jürgen Wellmann, Joachim Kremerskothen, Stefan Knecht, Katrin Guske, Agnes Flöel, Samira Schiwek, Kerstin Duning, Stefanie Jansen, Hubertus Lohmann, Veronica Witte, Sandra Hasenkamp, Claudia Hagedorn, Eva Brand

The rs17070145 polymorphism (C → T substitution, intron 9) of the KIBRA gene has recently been associated with episodic memory and cognitive flexibility. These findings were inconsistent across reports though, and largely lacked gene–gene or gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dfbb68a047dccdb9c6940a7ea351375
https://pub.uni-bielefeld.de/record/2537058

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KIBRA: A New Gateway to Learning and Memory?

Autor: Joachim Kremerskothen, Karoly Nikolich, Kerstin Duning, Robert Spoelgen, Matthew J. Huentelman, Armin Schneider

Publikováno v: Frontiers in Aging Neuroscience
Frontiers in Aging Neuroscience, Vol 2 (2010)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b5ceb1e1e0c2574231fee06e5132f8
https://pubmed.ncbi.nlm.nih.gov/20552044

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Hypertension in mice lacking the CXCR3 chemokine receptor

Autor: Ralph Telgmann, Truc Van Le, Hans Henning Meyer, Thomas Weide, Craig Gerard, Hermann Pavenstädt, Miriam Stölting, Stefan Martin Brand-Herrmann, Hsiang Hao Hsu, Kerstin Duning, Stefanie Kreusser, Martin J. Bek

Publikováno v: American journal of physiology. Renal physiology. 296(4)

The CXC chemokine receptor 3 (CXCR3) has been linked to autoimmune and inflammatory disease, allograft rejection, and ischemic nephropathy. CXCR3 is expressed on endothelial and smooth muscle cells. Although a recent study posited that antagonizing o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ff0bfc2edc905563b392f996bf713b
https://pubmed.ncbi.nlm.nih.gov/19129260

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