Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Kerstin Buck"'
Autor:
Natalie Landeck, Katherine E. Strathearn, Daniel Ysselstein, Kerstin Buck, Sayan Dutta, Siddhartha Banerjee, Zhengjian Lv, John D. Hulleman, Jagadish Hindupur, Li-Kai Lin, Sonal Padalkar, Lia A. Stanciu, Yuri L. Lyubchenko, Deniz Kirik, Jean-Christophe Rochet
Publikováno v:
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-23 (2020)
Abstract Background α-Synuclein (aSyn) aggregation is thought to play a central role in neurodegenerative disorders termed synucleinopathies, including Parkinson’s disease (PD). Mouse aSyn contains a threonine residue at position 53 that mimics th
Externí odkaz:
https://doaj.org/article/577ae13724214a3bac084228b03fe4b4
Publikováno v:
Neurobiology of Disease, Vol 78, Iss , Pp 100-114 (2015)
Phosphorylation of the α-synuclein (α-syn) protein at Ser129 [P(S129)-α-syn] was found to be the most abundant form in intracellular inclusions in brains from Parkinson's disease (PD) patients. This finding suggests that P(S129)-α-syn plays a cen
Externí odkaz:
https://doaj.org/article/e6cfc888a029486e90bd0c862951a4b1
Autor:
Kerstin Buck, Christoph Zydorek
Publikováno v:
KI in der digitalisierten Medienwirtschaft ISBN: 9783658374037
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::680b332dcdbc80dd473111e52fecd50d
https://doi.org/10.1007/978-3-658-37404-4_6
https://doi.org/10.1007/978-3-658-37404-4_6
Publikováno v:
Neurobiology of Disease, Vol 47, Iss 3, Pp 367-377 (2012)
Impairments in the capacity of dopaminergic neurons to handle cytoplasmic dopamine may be a critical factor underlying the selective vulnerability of midbrain dopamine neurons in Parkinson's disease. Furthermore, toxicity of α-synuclein in dopaminer
Externí odkaz:
https://doaj.org/article/a8e102550ec449b68a3c56ef464b2d61
Autor:
Kerstin Buck, Boris Ferger
Publikováno v:
Neurobiology of Disease, Vol 29, Iss 2, Pp 210-220 (2008)
l-3,4-dihydroxyphenylalanine (l-DOPA)-induced dyskinesia consists of involuntary choreiform and dystonic movements. Here we report whether intrastriatal l-DOPA itself is able to trigger dyskinetic behavior and which role the neurotransmitter dopamine
Externí odkaz:
https://doaj.org/article/0e1dfd65c5004b04b5b220963994274b
Autor:
Yuri L. Lyubchenko, Sonal Padalkar, John D. Hulleman, Siddhartha Banerjee, Li-Kai Lin, Lia Stanciu, Katherine E. Strathearn, Zhengjian Lv, Daniel Ysselstein, Deniz Kirik, Natalie Landeck, Kerstin Buck, Sayan Dutta, Jagadish Hindupur, Jean-Christophe Rochet
Publikováno v:
Molecular Neurodegeneration
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-23 (2020)
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-23 (2020)
Background α-Synuclein (aSyn) aggregation is thought to play a central role in neurodegenerative disorders termed synucleinopathies, including Parkinson’s disease (PD). Mouse aSyn contains a threonine residue at position 53 that mimics the human f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257bbb58937182c13adcfadc071c7413
https://pubmed.ncbi.nlm.nih.gov/32900375
https://pubmed.ncbi.nlm.nih.gov/32900375
Autor:
George P. McCabe, Siddhartha Banerjee, Kerstin Buck, Jean-Christophess Rochet, Zhengjian Lv, Katherine E. Strathearn, Li-Kai Lin, Yuri L. Lyubchenko, John D. Hulleman, Sayan Dutta, Natalie Landeck, Sonal Padalkar, Lia Stanciu, Deniz Kirik, Daniel Ysselstein, Jagadish Hindupur
α-Synuclein (aSyn) aggregation is thought to play a central role in neurodegenerative disorders termed synucleinopathies, including Parkinson’s disease (PD). Mouse aSyn contains a threonine residue at position 53 that mimics the human familial PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1640699a2db2538440fc7e73a4ff8214
https://doi.org/10.1101/700377
https://doi.org/10.1101/700377
Autor:
Natalie Landeck, Vladimir Mlynarik, Kerstin Buck, Sarah Sonnay, René in ‘t Zandt, Sandra Cuellar-Baena, Deniz Kirik
Publikováno v:
Journal of Neurochemistry. 137:806-819
In this study, we used proton-localized spectroscopy ((1) H-MRS) for the acquisition of the neurochemical profile longitudinally in a novel rat model of human wild-type alpha-synuclein (α-syn) over-expression. Our goal was to find out if the increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa8c5fcc2e2ffd7ec283f61ecae8e5a
https://doi.org/10.1111/jnc.13547
https://doi.org/10.1111/jnc.13547
Autor:
Laura Miesbauer, Karen Bodie, Ina Mairhofer, Bodo Janson, Marcus Meinhardt, Jonas Hoppe, Armin Keller, Gudrun Plotzky, Laura Gasparini, Jon D. Williams, Mario Mezler, Edith Beckenbach, David Holzinger, Roland G. Heym, Erica Barini, Kerstin Buck
Publikováno v:
Alzheimer's & Dementia. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d815341e92807ccbe3e537f04a7fe91
https://doi.org/10.1016/j.jalz.2018.06.1448
https://doi.org/10.1016/j.jalz.2018.06.1448
Intracellular inclusions made of filamentous aggregates of the microtubule-associated protein Tau are neuropathological hallmarks of Alzheimer disease and other neurodegenerative diseases collectively termed tauopathies, which include parasupranuclea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c733985b161d90a29abfcf16150f8c07
https://doi.org/10.1016/b978-0-12-811353-0.00070-1
https://doi.org/10.1016/b978-0-12-811353-0.00070-1