Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kerstin Breithaupt-Grögler"'
Autor:
Kerstin Breithaupt-Grögler, Tim Hardman, Jan de Hoon, Yves Donazzolo, Sylvie Rottey, Hildegard Sourgens, Steffan Stringer
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
The European Federation for Exploratory Medicines Development (EUFEMED) organized a meeting in Leuven, Belgium entitled ‘The new FIH EMA guideline: Disruptive or constructive?’ to provide a forum for stakeholders to discuss the guideline’s oper
Externí odkaz:
https://doaj.org/article/b23e4873d6a34cf49989b280af3ddd46
Autor:
Luc Van Bortel, Hildegard Sourgens, Kerstin Breithaupt-Grögler, Henri Caplain, Yves Donazzolo, Ingrid Klingmann, Michael Hammond, Timothy C. Hardman, Steffan Stringer, Jan de Hoon
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2018)
The first formal conference of the EUropean Federation for Exploratory MEdicines Development (EUFEMED) held in London was the result of a collaborative effort of its founding associations: the Association for Applied Human Pharmacology (AGAH; Germany
Externí odkaz:
https://doaj.org/article/e8d56503f6a649c0a713009e2c78b9b5
Autor:
Ingrid, Klingmann, Margit, Paul, Tamás, Bereczky, Ananda, Plate, Kerstin, Breithaupt-Grögler, Thomas M, Schindler, Jan, Geissler, T M, Schindler
Publikováno v:
Bundesgesundheitsblatt, Gesundheitsforschung, GesundheitsschutzLiteratur.
The currently valid Regulation (EU) 536/2014 on clinical trials with medicinal products for human use brings some innovations that are of great importance for patients who participate in clinical trials and patients with a need for innovative therapi
Autor:
Kerstin Breithaupt-Grögler, Timothy C. Hardman, Luc Van Bortel, Henri Caplain, Ingrid Klingmann, Michael Hammond, Hildegard Sourgens, Yves Donazzolo, Steffan Stringer, Jan de Hoon
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 8 (2018)
Frontiers in Pharmacology, Vol 8 (2018)
The first formal conference of the EUropean Federation for Exploratory MEdicines Development (EUFEMED) held in London was the result of a collaborative effort of its founding associations: the Association for Applied Human Pharmacology (AGAH; Germany
Autor:
Christian Hausdorf, Kerstin Breithaupt-Grögler, Winfried Fuchs, Gustav G Belz, Christian Mang, Raunhild Butzer
Publikováno v:
Journal of the Renin-Angiotensin-Aldosterone System, Vol 1 (2000)
Rationale A quantitative technique was used to compare the pharmacological potency in healthy volunteers of angiotensin II receptor antagonists (AIIA): candesartan cilexetil, losartan, irbesartan, valsartan, and telmisartan. Methods In a randomised,
Autor:
Claudius Malerczyk, Gustav G Belz, Kerstin Breithaupt-Grögler, Ernst Mutschler, Volker Herrmann, Hildegard Spahn-Langguth, Susanna Roll, Bettina Fuchs
Publikováno v:
Journal of Pharmacy and Pharmacology. 52:1075-1083
The angiotensin II antagonistic effects of candesartan and losartan were compared in-vivo after single and repeated doses. Effects were related to antagonistic activity in plasma. In this double-blind, crossover study, 12 healthy male volunteers rece
Autor:
Susanna Roll, Steffen G. Magin, Gustav G Belz, Claudius Malerczyk, Kerstin Breithaupt-Grögler, Ernst Mutschler, Anette Högemann, Barbara Voith, Bettina Fuchs, Volker Herrmann, Raunhild Butzer
Publikováno v:
British Journal of Clinical Pharmacology. 45:567-573
Aims The pharmacodynamic properties of the angiotensin II antagonist candesartan in humans were assessed from the rightward shifts of angiotensin II dose-effect curves (Schild regression technique). The pharmacokinetic characteristics were determined
Publikováno v:
BMC News and views. 3
Autor:
Kerstin Breithaupt-Grögler, Henning Blume, Georg Niebch, Katharina Erb, Gustav G Belz, Barbara Schug, Robert Hermann, Edith Schneider
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 8(1)
Thioctic acid (TA), a racemate of R-(+)- and S-(-)-enantiomers of alpha-lipoic acid, acts as a powerful lipophilic, free-radical scavenger and is used in the treatment of diabetic neuropathy. This trial investigated the dose-linearity of enantiomer p
Publikováno v:
Circulation. 96(8)
Background Epidemiological studies have suggested that garlic may have protective effects against cardiovascular diseases. We undertook this cross-sectional observational study to test the hypothesis that regular garlic intake would delay the stiffen