Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Kerstin Birod"'
Autor:
Susanne Schiffmann, Jessica Sandner, Ronald Schmidt, Kerstin Birod, Ivonne Wobst, Helmut Schmidt, Carlo Angioni, Gerd Geisslinger, Sabine Grösch
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 1, Pp 32-40 (2009)
Sphingolipids such as ceramides (Cers) play important roles in cell proliferation, apoptosis, and cell cycle regulation. An increased Cer level is linked to the cytotoxic effects of several chemotherapeutics. Various selective cyclooxygenase-2 (COX-2
Externí odkaz:
https://doaj.org/article/f5caba274d5f44caba4e7defd379fb55
Autor:
Quan Wang, Kerstin Birod, Carlo Angioni, Sabine Grösch, Tim Geppert, Petra Schneider, Matthias Rupp, Gisbert Schneider
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21554 (2011)
Molecular descriptors are essential for many applications in computational chemistry, such as ligand-based similarity searching. Spherical harmonics have previously been suggested as comprehensive descriptors of molecular structure and properties. We
Externí odkaz:
https://doaj.org/article/ece9470985644c8c990029b61a18db14
Autor:
Grösch, Khadija El-Hindi, Sebastian Brachtendorf, Jennifer Christina Hartel, Stephanie Oertel, Kerstin Birod, Nadine Merz, Sandra Trautmann, Dominique Thomas, Andreas Weigert, Tim J. Schäufele, Klaus Scholich, Susanne Schiffmann, Thomas Ulshöfer, Olaf Utermöhlen, Sabine
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1866
To better understand the role of sphingolipids in the multifactorial process of inflammatory bowel disease (IBD), we elucidated the role of CerS4 in colitis and colitis-associated cancer (CAC). For this, we utilized the azoxymethane/dextran sodium su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::0707a642c3d537b049fcd410d03cd4db
Autor:
Khadija El-Hindi, Sebastian Brachtendorf, Jennifer Christina Hartel, Stephanie Oertel, Kerstin Birod, Nadine Merz, Sandra Trautmann, Dominique Thomas, Andreas Weigert, Tim J. Schäufele, Klaus Scholich, Susanne Schiffmann, Thomas Ulshöfer, Olaf Utermöhlen, Sabine Grösch
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1866, p 1866 (2022)
To better understand the role of sphingolipids in the multifactorial process of inflammatory bowel disease (IBD), we elucidated the role of CerS4 in colitis and colitis-associated cancer (CAC). For this, we utilized the azoxymethane/dextran sodium su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f9a454a86c001c1cdaf6fa1b50c5f7b1
https://publica.fraunhofer.de/handle/publica/429324
https://publica.fraunhofer.de/handle/publica/429324
Autor:
Khadija El-Hindi, Kerstin Birod, Sabine Grösch, Jennifer Christina Hartel, Stephanie Oertel, Sebastian Brachtendorf, Andreas Weigert, Dominique Thomas, Thomas Ulshöfer, Martin Krönke, Olaf Utermöhlen, Sandra Trautmann
Publikováno v:
Cancers
Volume 12
Issue 7
Cancers, Vol 12, Iss 1753, p 1753 (2020)
Volume 12
Issue 7
Cancers, Vol 12, Iss 1753, p 1753 (2020)
Ceramide synthase 5 is one of six enzymes that catalyze the production of ceramides from sphingosine or sphinganine. Ceramides are important components of cell membranes and act as signaling molecules. Previously it has been shown that ceramide synth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5178df8a461e1c524032fb3f9933c55
http://europepmc.org/articles/PMC7409364
http://europepmc.org/articles/PMC7409364
Autor:
Sabine Grösch, Kerstin Birod, Dominique Thomas, Marthe-Susanna Wegner, Sandra Trautmann, Bernhard Brüne, Sebastian Brachtendorf, Ruth Anna Wanger, Gerd Geisslinger, Dominik C. Fuhrmann
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1863:1214-1227
Resistance against chemotherapy is a life-threatening complication in colon cancer therapy. To increase response rate, new additional targets that contribute to chemoresistance are still needed to be explored. Ceramides, which belong to the group of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40da9e16b2e2331aecbf709583100e02
https://doi.org/10.1016/j.bbalip.2018.07.011
https://doi.org/10.1016/j.bbalip.2018.07.011
Autor:
Yannick Schreiber, Gurumoorthy Krishnamoorthy, Kerstin Birod, Sabine Grösch, Klaus Willecke, Gerd Geisslinger, Philipp Ebel, Julia Männich, Max Eberle, Nadja Tafferner, Marthe-Susanna Wegner, Nerea Ferreirós, Susanne Schiffmann
Publikováno v:
Biochemical Pharmacology. 92:326-335
Ceramides (Cer) are mediators of inflammatory processes. In a chronic experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis (MS), we observed a significant elevation of C16-Cer and its synthesizing enzyme, ceramide synthase(CerS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b426e006dcdd1565bca756c580c7f1
https://doi.org/10.1016/j.bcp.2014.08.016
https://doi.org/10.1016/j.bcp.2014.08.016
Autor:
Max Eberle, Gerd Geisslinger, Julia Männich, Daniela Hartmann, Kerstin Birod, Ruth Anna Wanger, Nerea Ferreirós, Susanne Schiffmann, Sabine Grösch, Marthe-Susanna Wegner
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 45:1886-1894
Ceramides with different N-acyl chains can act as second messengers in various signaling pathways. They are involved in cell processes such as apoptosis, differentiation and inflammation. Ceramide synthases (CerS) are key enzymes in the biosynthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35e28ecf671a1d711dac04281ce2a609
https://doi.org/10.1016/j.biocel.2013.06.004
https://doi.org/10.1016/j.biocel.2013.06.004
Autor:
Sabine Grösch, Yannick Schreiber, Susanne Schiffmann, Sina Fuchs, Aleksandra Zivkovic, Kerstin Birod, Holger Stark, Gerd Geisslinger, Daniela Hartmann, Nerea Ferreirós
Publikováno v:
Biochimie. 94:558-565
Ceramide synthases (CerSs) are key enzymes in the biosynthesis of ceramides and display a group of at least six different isoenzymes (CerS1-6). Ceramides itself are bioactive molecules. Ceramides with different N-acyl side chains (C14:0-Cer – C26:0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e04d633e3a7b8aab38b2777ff0ef61f9
https://doi.org/10.1016/j.biochi.2011.09.007
https://doi.org/10.1016/j.biochi.2011.09.007
Autor:
Susanne Schiffmann, Daniela Hartmann, Sina Rode, Kerstin Birod, Carlo Angioni, Sabine Grösch, Simone Ziebell, Jessica Sandner, Klaus Deckmann, Helmut Schmidt, Gerd Geisslinger
Publikováno v:
Biochemical Pharmacology. 80:1632-1640
Ceramides serve as bioactive molecules with important roles in cell proliferation and apoptosis. Ceramides (Cer) with different N-acyl side chains (C 14:0 -Cer–C 26:0 -Cer) possess distinctive roles in cell signaling and are differentially expresse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b256abf09bdfdd14d1deef32191ec1dd
https://doi.org/10.1016/j.bcp.2010.08.012
https://doi.org/10.1016/j.bcp.2010.08.012