Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kerstin B. E. Ohlson"'
Autor:
Sten G. E. Lindahl, Kerstin B. E. Ohlson, Emma C. Backlund, G. E. Bronnikov, Jan Nedergaard, Nina Mohell, Barbara Cannon, Irina G. Shabalina, Katarina Lennström
Publikováno v:
Biochemical Pharmacology. 68:463-477
Volatile anesthetics such as halothane efficiently inhibit nonshivering thermogenesis as well as the cellular manifestation of that phenomenon: norepinephrine-induced respiration in brown adipocytes. To identify the molecular site(s) of action of suc
Autor:
Anita Matthias, Jan Nedergaard, Barbara Cannon, Anders Jacobsson, Kerstin B. E. Ohlson, J. M. Fredriksson
Publikováno v:
Journal of Biological Chemistry. 275:25073-25081
To examine the thermogenic significance of the classical uncoupling protein-1 (UCP1), the thermogenic potential of brown adipocytes isolated from UCP1-ablated mice was investigated. Ucp1(-/-) cells had a basal metabolic rate identical to wild-type; t
Publikováno v:
Scopus-Elsevier
In infants, nonshivering thermogenesis from brown adipose tissue provides an important source of heat for thermoregulation. Infants are known to have a high susceptibility to hypothermia during anesthesia. To investigate whether this could be due to
Publikováno v:
Anesthesiology. 98(2)
Background This investigation examined the possibility that the inhibitory effect of halothane on nonshivering thermogenesis (heat production) in brown adipocytes is not a universal effect of all anesthetic agents but related to the type of anestheti
Autor:
Jan Nedergaard, Kerstin B. E. Ohlson, Barbara Cannon, Anders Jacobsson, Anita Matthias, Valeria Golozoubova
Publikováno v:
Life in the Cold ISBN: 9783642086823
The original uncoupling protein UCP1 (thermogenin) is only found in brown adipose tissue which is only found in mammals. UCP1 is supposed to be the molecular basis for nonshivering thermogenesis. This tenet can be tested in the UCP1-ablated mice now
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::393ee1ae102e61736ad7f54aef965ebf
https://doi.org/10.1007/978-3-662-04162-8_42
https://doi.org/10.1007/978-3-662-04162-8_42
Publikováno v:
Annals of the New York Academy of Sciences. 813
In the present studies, halothane is demonstrated to have a general inhibitory effect on norepinephrine-induced cAMP accumulation, lipolysis and rate of oxygen consumption, but no obvious effect on the respiratory capacity of isolated mitochondria. F
Autor:
Jan Nedergaard, Sten G. E. Lindahl, Lennart Johnson, Andrea Dicker, Kerstin B. E. Ohlson, Barbara Cannon
Publikováno v:
Anesthesiology. 82(2)
BACKGROUND During halothane anesthesia, infants fail to increase oxygen consumption in response to a cold stimulus in the form of an increase in temperature gradient between body and environment. Based on recent observations with isolated brown-fat c