Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kerstin, Schütze"'
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 15403 (2022)
Transplantation of allogeneic hematopoietic stem cells represents an established treatment for children with high-risk leukemia. However, steroid-refractory chronic graft-versus-host disease (SR-cGvHD) represents a severe life-threatening complicatio
Externí odkaz:
https://doaj.org/article/b213555fa8ea44f6b4aa924546cad254
Autor:
Kerstin Schütze, Katharina Petry, Julia Hambach, Niklas Schuster, William Fumey, Levin Schriewer, Jana Röckendorf, Stephan Menzel, Birte Albrecht, Friedrich Haag, Catelijne Stortelers, Peter Bannas, Friedrich Koch-Nolte
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
CD38 is overexpressed by multiple myeloma cells and has emerged as a target for therapeutic antibodies. Nanobodies are soluble single domain antibody fragments derived from the VHH variable domain of heavy chain antibodies naturally occurring in came
Externí odkaz:
https://doaj.org/article/73386a564c9a465d8f987c717ce73431
Autor:
Julia Hambach, Kristoffer Riecken, Sophia Cichutek, Kerstin Schütze, Birte Albrecht, Katharina Petry, Jana Larissa Röckendorf, Natalie Baum, Nicolaus Kröger, Timon Hansen, Gunter Schuch, Friedrich Haag, Gerhard Adam, Boris Fehse, Peter Bannas, Friedrich Koch-Nolte
Publikováno v:
Cells, Vol 9, Iss 2, p 321 (2020)
The NAD-hydrolyzing ecto-enzyme CD38 is overexpressed by multiple myeloma and other hematological malignancies. We recently generated CD38-specific nanobodies, single immunoglobulin variable domains derived from heavy-chain antibodies naturally occur
Externí odkaz:
https://doaj.org/article/45aa97fe88f54d0990491ef3c162f04d
Autor:
Kerstin Schütze, Miriam Groß, Kerstin Cornils, Katharina Wustrau, Sonja Schneppenheim, Henning Lenhartz, G. Christoph Korenke, Gritta Janka, Svea Ledig, Ingo Müller, Stephan Ehl, Kai Lehmberg
Publikováno v:
Blood advances.
Most hereditary forms of hemophagocytic lymphohistiocytosis (HLH) are caused by defects of cytotoxicity, including the vesicle trafficking disorder Griscelli syndrome type 2 (GS2, RAB27A deficiency). Deficiency of the mitogen-activated protein kinase
Autor:
Anna Oberle, Anna Brandt, Malik Alawi, Claudia Langebrake, Snjezana Janjetovic, Christine Wolschke, Kerstin Schütze, Peter Bannas, Nicolaus Kröger, Friedrich Koch-Nolte, Carsten Bokemeyer, Mascha Binder
Publikováno v:
Haematologica, Vol 102, Iss 9 (2017)
Externí odkaz:
https://doaj.org/article/5c70616cb8f34e96af6fe21af717ee6a
Autor:
Peter Bannas, Timon Hansen, Nicolaus Kröger, Björn Rissiek, Katharina Petry, Friedrich Koch-Nolte, Mascha Binder, Boris Fehse, Julia Koenigsdorf, Levin Schriewer, Birte Albrecht, William Fumey, Jana Larissa Röckendorf, Francis Ayuk, Kerstin Schütze, Gunter Schuch, Friedrich Haag, Stephan Menzel, Gerhard Adam, Hans O. Pinnschmidt, Kristoffer Riecken, Joanna Schmid, Natalie Baum, Julia Hambach
Publikováno v:
Theranostics
Rationale: CD38 is a target for the therapy of multiple myeloma (MM) with monoclonal antibodies such as daratumumab and isatuximab. Since MM patients exhibit a high rate of relapse, the development of new biologics targeting alternative CD38 epitopes
Autor:
Alexander Lenz, Harald Ittrich, Friedrich Koch-Nolte, William Fumey, Valentin Kunick, Gerhard Adam, Anna Marei Eichhoff, Lennart Well, Björn Rissiek, Martin Trepel, Kerstin Schütze, Friedrich Haag, Joanna Schmid, Peter Bannas
Publikováno v:
Contrast Media & Molecular Imaging. 10:367-378
The utility of nanobodies and conventional antibodies for in vivo imaging is well known, but optimum dosing and timing schedules for one versus the other have not been established. We aimed to improve specific tumor imaging in vivo with nanobodies an
Autor:
William, Fumey, Julia, Koenigsdorf, Valentin, Kunick, Stephan, Menzel, Kerstin, Schütze, Mandy, Unger, Levin, Schriewer, Friedrich, Haag, Gerhard, Adam, Anna, Oberle, Mascha, Binder, Ralf, Fliegert, Andreas, Guse, Yong Juan, Zhao, Hon, Cheung Lee, Fabio, Malavasi, Fernando, Goldbaum, Rob, van Hegelsom, Catelijne, Stortelers, Peter, Bannas, Friedrich, Koch-Nolte
Publikováno v:
Scientific Reports
The cell surface ecto-enzyme CD38 is a promising target antigen for the treatment of hematological malignancies, as illustrated by the recent approval of daratumumab for the treatment of multiple myeloma. Our aim was to evaluate the potential of CD38
Autor:
Friedrich Koch-Nolte, Ralf Fliegert, Kerstin Schütze, Mandy Unger, Friedrich Haag, Valentin Kunick, Fernando Alberto Goldbaum, Andreas H. Guse, Fabio Malavasi, William Fumey, Peter Bannas, Hon Cheung Lee, Rob van Hegelsom, Levin Schriewer, Yong Juan Zhao, Stephan Menzel, Anna Oberle, Gerhard Adam, Julia Koenigsdorf, Mascha Binder, Catelijne Stortelers
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
The cell surface ecto-enzyme CD38 is a promising target antigen for the treatment of hematological malignancies, as illustrated by the recent approval of daratumumab for the treatment of multiple myeloma. Our aim was to evaluate the potential of CD38
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4df67fb921991a528aa6a4feae0aaea2
http://hdl.handle.net/2318/1654403
http://hdl.handle.net/2318/1654403
Autor:
Peter, Bannas, Alexander, Lenz, Valentin, Kunick, Lennart, Well, William, Fumey, Björn, Rissiek, Friedrich, Haag, Joanna, Schmid, Kerstin, Schütze, Anna, Eichhoff, Martin, Trepel, Gerhard, Adam, Harald, Ittrich, Friedrich, Koch-Nolte
Publikováno v:
Contrast mediamolecular imaging. 10(5)
The utility of nanobodies and conventional antibodies for in vivo imaging is well known, but optimum dosing and timing schedules for one versus the other have not been established. We aimed to improve specific tumor imaging in vivo with nanobodies an