Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Kerstin, Sarter"'
Autor:
Yasunori Omata, Hiroyuki Okada, Steffen Uebe, Naohiro Izawa, Arif B. Ekici, Kerstin Sarter, Taku Saito, Georg Schett, Sakae Tanaka, Mario M. Zaiss
Publikováno v:
JBMR Plus, Vol 6, Iss 7, Pp n/a-n/a (2022)
ABSTRACT Bone turnover is finely tuned by cells in the bone milieu, including osteoblasts, osteoclasts, and osteocytes. Osteoclasts are multinucleated giant cells with a bone‐resorbing function that play a critical role in regulating skeletal homeo
Externí odkaz:
https://doaj.org/article/6cbfdb6971e440e7af6ee572be7528b2
Autor:
Narges Tajik, Michael Frech, Oscar Schulz, Fabian Schälter, Sébastien Lucas, Vugar Azizov, Kerstin Dürholz, Franziska Steffen, Yasunori Omata, Andreas Rings, Marko Bertog, Aroldo Rizzo, Aida Iljazovic, Marijana Basic, Arnd Kleyer, Stephan Culemann, Gerhard Krönke, Yubin Luo, Klaus Überla, Udo S. Gaipl, Benjamin Frey, Till Strowig, Kerstin Sarter, Stephan C. Bischoff, Stefan Wirtz, Juan D. Cañete, Francesco Ciccia, Georg Schett, Mario M. Zaiss
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Intestinal dysbiosis is associated with an ever-growing list of autoimmune diseases. Here the authors show that both mice and humans with autoimmune arthritis can have dysbiosis and barrier leakiness prior to major signs of inflammatory arthritis, an
Externí odkaz:
https://doaj.org/article/85f50113935441358e580e8e7a413f86
Autor:
Vugar Azizov, Katharina Dietel, Franziska Steffen, Kerstin Dürholz, Julia Meidenbauer, Sébastien Lucas, Michael Frech, Yasunori Omata, Narges Tajik, Lisa Knipfer, Anne Kolenbrander, Silvia Seubert, Dennis Lapuente, Maria V. Sokolova, Jörg Hofmann, Matthias Tenbusch, Andreas Ramming, Ulrike Steffen, Falk Nimmerjahn, Ralf Linker, Stefan Wirtz, Martin Herrmann, Vladimir Temchura, Kerstin Sarter, Georg Schett, Mario M. Zaiss
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Moderate consumption of alcohol is associated with protection from some autoimmune diseases. Here the authors show that ethanol and its metabolite acetate can protect mice from collagen-induced arthritis and provide evidence that the mechanism of thi
Externí odkaz:
https://doaj.org/article/eeef82bd54c54d9ebcc3a76561c3042f
Autor:
Michael Frech, Yasunori Omata, Angelika Schmalzl, Stefan Wirtz, Leila Taher, Georg Schett, Mario M. Zaiss, Kerstin Sarter
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Innate lymphoid cells (ILC) not only are responsible for shaping the innate immune response but also actively modulate T cell responses. However, the molecular processes regulating ILC-T cell interaction are not yet completely understood. The protein
Externí odkaz:
https://doaj.org/article/ea3248d47e2c47949c48613beac0cd98
Autor:
Michael Frech, Gregor Schuster, Fabian T. Andes, Georg Schett, Mario M. Zaiss, Kerstin Sarter
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Butyrophilins, which are members of the extended B7 family of immunoregulators structurally related to the B7 family, have diverse functions on immune cells as co-stimulatory and co-inhibitory molecules. Despite recent advances in the understanding o
Externí odkaz:
https://doaj.org/article/51352d8a5e4749bba5ff32647ec64401
Autor:
Yasunori Omata, Michael Frech, Tatjana Primbs, Sébastien Lucas, Darja Andreev, Carina Scholtysek, Kerstin Sarter, Markus Kindermann, Nataliya Yeremenko, Dominique L. Baeten, Nico Andreas, Thomas Kamradt, Aline Bozec, Andreas Ramming, Gerhard Krönke, Stefan Wirtz, Georg Schett, Mario M. Zaiss
Publikováno v:
Cell Reports, Vol 24, Iss 1, Pp 169-180 (2018)
Summary: Group 2 innate lymphoid cells (ILC2s) were detected in the peripheral blood and the joints of rheumatoid arthritis (RA) patients, serum-induced arthritis (SIA), and collagen-induced arthritis (CIA) using flow cytometry. Circulating ILC2s wer
Externí odkaz:
https://doaj.org/article/887aecb0527247c7819b597695f65869
Autor:
Sébastien Lucas, Yasunori Omata, Jörg Hofmann, Martin Böttcher, Aida Iljazovic, Kerstin Sarter, Olivia Albrecht, Oscar Schulz, Brenda Krishnacoumar, Gerhard Krönke, Martin Herrmann, Dimitrios Mougiakakos, Till Strowig, Georg Schett, Mario M. Zaiss
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Short-chain fatty acids (SCFA) are a main class of metabolites derived from fermentation of dietary fibre in the intestine. Here, the authors show that dietary administration of SCFA is associated with inhibition of osteoclast differentiation, increa
Externí odkaz:
https://doaj.org/article/08d47d8f88be44b4963529fd15837407
Publikováno v:
Autoimmunity, Vol 50, Iss 3, Pp 151-157 (2017)
Infections with different helminth species have been observed to ameliorate a variety of chronic inflammatory diseases. Herein, we show that the natural murine helminth species, Heligmosomoides polygyrus bakeri (Hp) is capable of attenuating disease
Externí odkaz:
https://doaj.org/article/5f572faac1e440d0a5f84e4842744b86
Autor:
Klaus W. Frommer, Rebecca Hasseli, Andreas Schäffler, Uwe Lange, Stefan Rehart, Jürgen Steinmeyer, Markus Rickert, Kerstin Sarter, Mario M. Zaiss, Carsten Culmsee, Goutham Ganjam, Susanne Michels, Ulf Müller-Ladner, Elena Neumann
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Obesity—in which free fatty acid (FFA) levels are chronically elevated—is a known risk factor for different rheumatic diseases, and obese patients are more likely to develop osteoarthritis (OA) also in non-weight-bearing joints. These findings su
Externí odkaz:
https://doaj.org/article/c224794e97364eddb327455091429405
Autor:
Udo S. Gaipl, Vugar Azizov, Benjamin Frey, Mario M. Zaiss, Francesco Ciccia, Klaus Überla, Michael Frech, Kerstin Sarter, Aroldo Rizzo, Arnd Kleyer, Marko Bertog, Yubin Luo, Georg Schett, Kerstin Dürholz, Yasunori Omata, Andreas Rings, Franziska Steffen, Oscar Schulz, Marijana Basic, Gerhard Krönke, Stephan Culemann, Till Strowig, Fabian Schälter, Stephan C. Bischoff, Narges Tajik, Juan D. Cañete, Stefan Wirtz, Sébastien Lucas, Aida Iljazovic
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature communications
England
Nature Communications
Nature communications
England
Gut microbial dysbiosis is associated with the development of autoimmune disease, but the mechanisms by which microbial dysbiosis affects the transition from asymptomatic autoimmunity to inflammatory disease are incompletely characterized. Here, we i