Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kerstin, Fella"'
Autor:
Kerstin Fella, Michael Karas, Dietmar Waidelich, Matthias Glückmann, Michaela Kröger, Dietrich Merkel, Volker Kruft, Peter-Jürgen Kramer, Yvonne Walter, Jürgen Hellmann
Publikováno v:
PROTEOMICS. 7:1564-1574
Today, toxicoproteomics still relies mainly on 2-DE followed by MS for detection and identification of proteins, which might characterize a certain state of disease, indicate toxicity or even predict carcinogenicity. We utilized the classical 2-DE/MS
Autor:
Kerstin Fella, Jürgen Hellmann, Michael Karas, Michaela Kröger, Matthias Glückmann, P.-J. Kramer
Publikováno v:
PROTEOMICS. 5:1914-1927
Our current approach focused on the identification of potential early protein biomarker signatures which are indicative of the carcinogenic processes in rats exposed to 20 mg/kg of the liver carcinogen N-nitrosomorpholine (NNM). Treated liver was inv
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 22(1)
The use of animal models in pharmaceutical research is a costly and sometimes misleading method of generating toxicity data and hence predicting human safety. Therefore, in vitro test systems, such as primary rat hepatocytes, and the developing genom
Autor:
Michaela, Kröger, Jürgen, Hellmann, Luca, Toldo, Matthias, Glückmann, Bettina, von Eiff, Kerstin, Fella, Peter-Jürgen, Kramer
Publikováno v:
ALTEX. 21
The rapid development of molecular toxicology is providing innovative approaches to an improved investigation and recognition of toxic substances. Proteome analysis offers, with 2DE/MS (two-dimensional gel electrophoresis and mass spectrometry) and S