Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Kerstin, Bartscherer"'
Autor:
Tim Koopmans, Henriette van Beijnum, Elke F. Roovers, Antonio Tomasso, Divyanshu Malhotra, Jochem Boeter, Olympia E. Psathaki, Danielle Versteeg, Eva van Rooij, Kerstin Bartscherer
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-16 (2021)
Abstract Ischemic heart disease and by extension myocardial infarction is the primary cause of death worldwide, warranting regenerative therapies to restore heart function. Current models of natural heart regeneration are restricted in that they are
Externí odkaz:
https://doaj.org/article/679c838b47c14a9493266eb88940b458
Autor:
Gerard W. Dougherty, Katsutoshi Mizuno, Tabea Nöthe-Menchen, Yayoi Ikawa, Karsten Boldt, Asaf Ta-Shma, Isabella Aprea, Katsura Minegishi, Yuan-Ping Pang, Petra Pennekamp, Niki T. Loges, Johanna Raidt, Rim Hjeij, Julia Wallmeier, Huda Mussaffi, Zeev Perles, Orly Elpeleg, Franziska Rabert, Hidetaka Shiratori, Stef J. Letteboer, Nicola Horn, Samuel Young, Timo Strünker, Friederike Stumme, Claudius Werner, Heike Olbrich, Katsuyoshi Takaoka, Takahiro Ide, Wang Kyaw Twan, Luisa Biebach, Jörg Große-Onnebrink, Judith A. Klinkenbusch, Kavita Praveen, Diana C. Bracht, Inga M. Höben, Katrin Junger, Jana Gützlaff, Sandra Cindrić, Micha Aviram, Thomas Kaiser, Yasin Memari, Petras P. Dzeja, Bernd Dworniczak, Marius Ueffing, Ronald Roepman, Kerstin Bartscherer, Nicholas Katsanis, Erica E. Davis, Israel Amirav, Hiroshi Hamada, Heymut Omran
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
The mechanism by which adenosine monophosphate modulates dynein ATPase-mediated ciliary and flagellar beating remains obscure. Here the authors identify an axonemal module including cilia and flagella associated protein 45 that supports adenine nucle
Externí odkaz:
https://doaj.org/article/ab0a6ca10924497e88909fc70b971840
Autor:
Phong D. Nguyen, Iris Gooijers, Giulia Campostrini, Arie O. Verkerk, Hessel Honkoop, Mara Bouwman, Dennis E. M. de Bakker, Tim Koopmans, Aryan Vink, Gerda E. M. Lamers, Avraham Shakked, Jonas Mars, Aat A. Mulder, Sonja Chocron, Kerstin Bartscherer, Eldad Tzahor, Christine L. Mummery, Teun P. de Boer, Milena Bellin, Jeroen Bakkers
Publikováno v:
Science, 380(6646), 758-764. American Association for the Advancement of Science
Zebrafish hearts can regenerate by replacing damaged tissue with new cardiomyocytes. Although the steps leading up to the proliferation of surviving cardiomyocytes have been extensively studied, little is known about the mechanisms that control proli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::943bee9c72057afcf68114b824ca5b6c
https://doi.org/10.1126/science.abo6718
https://doi.org/10.1126/science.abo6718
Autor:
Suthira Owlarn, Felix Klenner, David Schmidt, Franziska Rabert, Antonio Tomasso, Hanna Reuter, Medhanie A. Mulaw, Sören Moritz, Luca Gentile, Gilbert Weidinger, Kerstin Bartscherer
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Some wounds trigger regeneration, while others simply heal but how this is regulated is unclear. Here, by manipulating ERK and Wnt signalling pathways, the authors create headless planarians and finless zebrafish and show that wounds that normally on
Externí odkaz:
https://doaj.org/article/e4121786dfd84d7e91076c345878d239
Autor:
David Schmidt, Hanna Reuter, Katja Hüttner, Larissa Ruhe, Franziska Rabert, Florian Seebeck, Manuel Irimia, Jordi Solana, Kerstin Bartscherer
Publikováno v:
PLoS Genetics, Vol 14, Iss 12, p e1007828 (2018)
In multicellular organisms, cell type diversity and fate depend on specific sets of transcript isoforms generated by post-transcriptional RNA processing. Here, we used Schmidtea mediterranea, a flatworm with extraordinary regenerative abilities and a
Externí odkaz:
https://doaj.org/article/1f3e107389fb419b95dbb07023693a46
Autor:
Hanna Reuter, Martin März, Matthias C. Vogg, David Eccles, Laura Grífol-Boldú, Daniel Wehner, Suthira Owlarn, Teresa Adell, Gilbert Weidinger, Kerstin Bartscherer
Publikováno v:
Cell Reports, Vol 10, Iss 2, Pp 253-265 (2015)
Wnt/β-catenin signaling regulates tissue homeostasis and regeneration in metazoans. In planarians—flatworms with high regenerative potential—Wnt ligands are thought to control tissue polarity by shaping a β-catenin activity gradient along the a
Externí odkaz:
https://doaj.org/article/7ee3519e493d4fb8a16e1158fc5daa07
Autor:
Rafael Romero, Sheila Cárcel, Judith Mazariegos, Coral Vivancos, Kerstin Bartscherer, Susanna Fraguas, Thileepan Sekaran, Jordi Ginés, Ma Dolores Molina, Francesc Cebrià
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Developmental Biology, 476, 53-67. Academic Press
Universidad de Barcelona
Developmental Biology, 476, 53-67. Academic Press
In developmental biology, the regulation of stem cell plasticity and differentiation remains an open question. CBP(CREB-binding protein)/p300 is a conserved gene family that functions as a transcriptional co-activator and plays important roles in a w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb1f817d3a2e99c473b1939eed0511b1
https://doi.org/10.1016/j.ydbio.2021.02.008
https://doi.org/10.1016/j.ydbio.2021.02.008
Publikováno v:
bioRxiv-pre
bioRxiv
bioRxiv
Although most mammals heal wounds with scar tissue, spiny mice (Acomys cahirinus) naturally regenerate skin and complex musculoskeletal tissues. The core signaling pathways driving mammalian tissue regeneration are poorly characterized. Here, we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b0967574131e4d5f32c7d9a9c7640f
https://doi.org/10.1101/2022.06.27.497314
https://doi.org/10.1101/2022.06.27.497314
Autor:
Alexander Böser, Hannes C.A. Drexler, Hanna Reuter, Henning Schmitz, Guangming Wu, Hans R. Schöler, Luca Gentile, Kerstin Bartscherer
Publikováno v:
Cell Reports, Vol 5, Iss 4, Pp 1142-1155 (2013)
Planarian regeneration depends on the presence of pluripotent stem cells in the adult. We developed an in vivo stable isotope labeling by amino acids in cell culture (SILAC) protocol in planarians to identify proteins that are enriched in planarian s
Externí odkaz:
https://doaj.org/article/017b7055c3274b03843a2bfd69dcb44f
Publikováno v:
Disease Models & Mechanisms, Vol 4, Iss 1, Pp 12-19 (2011)
Planarian flatworms are an exception among bilaterians in that they possess a large pool of adult stem cells that enables them to promptly regenerate any part of their body, including the brain. Although known for two centuries for their remarkable r
Externí odkaz:
https://doaj.org/article/5048f0badc294ec392f02cd55db4f724