Molecular and cellular signatures underlying superior immunity against Bordetella pertussis upon pulmonary vaccination.

Autor: Raeven RH; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands.; Division of Drug Delivery Technology, Cluster BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden, The Netherlands., Brummelman J; Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.; Department of Infectious Diseases and Immunology, Utrecht University, Utrecht, The Netherlands., Pennings JLA; Centre for Health Protection, National Institute for Public Health and the Environment, Bilthoven, The Netherlands., van der Maas L; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands., Helm K; Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands., Tilstra W; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands., van der Ark A; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands., Sloots A; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands., van der Ley P; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands., van Eden W; Department of Infectious Diseases and Immunology, Utrecht University, Utrecht, The Netherlands., Jiskoot W; Division of Drug Delivery Technology, Cluster BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden, The Netherlands., van Riet E; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands., van Els CA; Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands., Kersten GF; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands.; Division of Drug Delivery Technology, Cluster BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden, The Netherlands., Han WG; Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands., Metz B; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands.

Publikováno v: Mucosal immunology [Mucosal Immunol] 2018 May; Vol. 11 (3), pp. 979-993. Date of Electronic Publication: 2017 Sep 20.

Bordetella pertussis outer membrane vesicle vaccine confers equal efficacy in mice with milder inflammatory responses compared to a whole-cell vaccine.

Autor: Raeven RH; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands.; Division of Drug Delivery Technology, Leiden Academic Centre for Drug Research, Leiden, The Netherlands., Brummelman J; Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands., Pennings JL; Centre for Health Protection (GZB), National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands., van der Maas L; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands., Tilstra W; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands., Helm K; Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands., van Riet E; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands., Jiskoot W; Division of Drug Delivery Technology, Leiden Academic Centre for Drug Research, Leiden, The Netherlands., van Els CA; Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands., Han WG; Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands., Kersten GF; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands.; Division of Drug Delivery Technology, Leiden Academic Centre for Drug Research, Leiden, The Netherlands., Metz B; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands.

Publikováno v: Scientific reports [Sci Rep] 2016 Dec 01; Vol. 6, pp. 38240. Date of Electronic Publication: 2016 Dec 01.

The Production of a Stable Infliximab Powder: The Evaluation of Spray and Freeze-Drying for Production.

Autor: Kanojia G; Intravacc (Institute for Translational Vaccinology), Bilthoven, The Netherlands.; University of Groningen, Department of Pharmaceutical Technology and Biopharmacy, Groningen, The Netherlands., Have RT; Intravacc (Institute for Translational Vaccinology), Bilthoven, The Netherlands., Bakker A; AIMM Therapeutics, Amsterdam, The Netherlands., Wagner K; AIMM Therapeutics, Amsterdam, The Netherlands., Frijlink HW; University of Groningen, Department of Pharmaceutical Technology and Biopharmacy, Groningen, The Netherlands., Kersten GF; Intravacc (Institute for Translational Vaccinology), Bilthoven, The Netherlands.; Leiden Academic Centre of Drug Research, Drug Delivery Technology, Leiden, The Netherlands., Amorij JP; Intravacc (Institute for Translational Vaccinology), Bilthoven, The Netherlands.

Publikováno v: PloS one [PLoS One] 2016 Oct 05; Vol. 11 (10), pp. e0163109. Date of Electronic Publication: 2016 Oct 05 (Print Publication: 2016).

Influenza Vaccine Manufacturing: Effect of Inactivation, Splitting and Site of Manufacturing. Comparison of Influenza Vaccine Production Processes.

Autor: Kon TC; Department of Product Development, Intravacc, Institute for Translational Vaccinology, Bilthoven, The Netherlands., Onu A; Laboratory of Biotechnology, Cantacuzino National Research Institute, Bucharest, Romania., Berbecila L; Unit of Influenza Vaccine Production, Cantacuzino National Research Institute, Bucharest, Romania., Lupulescu E; Laboratory of Respiratory Viral Infections, Cantacuzino National Research Institute, Bucharest, Romania., Ghiorgisor A; Laboratory of Respiratory Viral Infections, Cantacuzino National Research Institute, Bucharest, Romania., Kersten GF; Department of Research, Intravacc, Institute for Translational Vaccinology, Bilthoven, The Netherlands., Cui YQ; Department of Product Development, Intravacc, Institute for Translational Vaccinology, Bilthoven, The Netherlands., Amorij JP; Department of Business Development, Intravacc, Institute for Translational Vaccinology, Bilthoven, The Netherlands., Van der Pol L; Department of Research, Intravacc, Institute for Translational Vaccinology, Bilthoven, The Netherlands.

Publikováno v: PloS one [PLoS One] 2016 Mar 09; Vol. 11 (3), pp. e0150700. Date of Electronic Publication: 2016 Mar 09 (Print Publication: 2016).

Current and next generation influenza vaccines: Formulation and production strategies.

Autor: Soema PC; Intravacc (Institute for Translational Vaccinology), Bilthoven, The Netherlands; Division of Drug Delivery and Technology, Leiden Academic Centre for Drug Research, Leiden University, The Netherlands., Kompier R; Intravacc (Institute for Translational Vaccinology), Bilthoven, The Netherlands; FluConsult, Noordwijk, The Netherlands., Amorij JP; Intravacc (Institute for Translational Vaccinology), Bilthoven, The Netherlands. Electronic address: jean-pierre.amorij@intravacc.nl., Kersten GF; Intravacc (Institute for Translational Vaccinology), Bilthoven, The Netherlands; Division of Drug Delivery and Technology, Leiden Academic Centre for Drug Research, Leiden University, The Netherlands.

Publikováno v: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V [Eur J Pharm Biopharm] 2015 Aug; Vol. 94, pp. 251-63. Date of Electronic Publication: 2015 Jun 03.