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Autor:
Kersten D. Landa, Esther Oomen-de Hoop, Marthe S. Paats, G.D. Marijn Veerman, Ron H.J. Mathijssen, Robert Peric, Anne-Marie C. Dingemans, Teun van Gelder, Cor van der Leest, Suzanna D. Broerse, Stijn L.W. Koolen, Hugo B. Rutten, Christi M.J. Steendam, Huub Belderbos, Koen G. A. M. Hussaarts, Roelof W F van Leeuwen, Joachim G.J.V. Aerts
Publikováno v:
Clinical Pharmacokinetics
Clinical Pharmacokinetics, 60(1), 69-77. Adis
Clinical Pharmacokinetics, 60(1), 69-77. Adis
Introduction: Erlotinib’s gastrointestinal solubility and absorption are decreased by proton pump inhibitors (PPIs). Since erlotinib is a lipophilic drug, we hypothesized that concomitant intake with the fatty beverage milk may be a feasible way to