Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kerry Tyson"'
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
The propensity for some monoclonal antibodies (mAbs) to aggregate at physiological and manufacturing pH values can prevent their use as therapeutic molecules or delay time to market. Consequently, developability assessments are essential to select op
Externí odkaz:
https://doaj.org/article/ae4bb49c558444769fdeb77ccc96bfe5
Autor:
Suzanne Cole, Janine Murray, Catherine Simpson, Remi Okoye, Kerry Tyson, Meryn Griffiths, Dominique Baeten, Stevan Shaw, Asher Maroof
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
IL-23 is considered a critical regulator of IL-17 in Th17 cells; however, its requirement for inducing IL-17 production in other human immune subsets remains incompletely understood. Mucosal associated invariant T (MAIT) cells uniformly express retin
Externí odkaz:
https://doaj.org/article/9977591d4c7042d0b21fe34563635126
Autor:
Daniel, Lightwood, Victoria, O'Dowd, Bruce, Carrington, Vaclav, Veverka, Mark D, Carr, Markus, Tservistas, Alistair J, Henry, Bryan, Smith, Kerry, Tyson, Sabrina, Lamour, Marguerite, Bracher, Kaushik, Sarkar, Alison, Turner, Alastair D, Lawson, Tim, Bourne, Neil, Gozzard, Roger, Palframan
Publikováno v:
Journal of Molecular Biology. 425:577-593
We describe the discovery, engineering and characterisation of a highly potent anti-human interleukin (IL)-13 Fab fragment designed for administration by inhalation. The lead candidate molecule was generated via a novel antibody discovery process, an
Autor:
Sonal, Patel, Paul R, Turner, Colin, Stubberfield, Eleanor, Barry, Christian R, Rohlff, Alasdair, Stamps, Edward, McKenzie, Kathryn, Young, Kerry, Tyson, Jon, Terrett, Gary, Box, Suzanne, Eccles, Martin J, Page
Publikováno v:
International Journal of Cancer. 97:416-424
The mRNA levels of hyal-1, hyal-2, LUCA3 and PH20, the 4 hyaluronidases with demonstrated endoglucosaminidase activity, were extensively profiled in normal and tumor tissues and cell lines, using dot blot analysis and quantitative PCR. In normal tiss
Autor:
Evangelis Efthimiou, Ekaterina Blaveri, Paola Capelli, Melanie Jones, Antonella Baron, Benoit Terris, Aldo Scarpa, Nicholas R. Lemoine, Claudio Bassi, Tatjana Crnogorac-Jurcevic, Kerry Tyson
Gene expression studies were undertaken in normal pancreas and pancreatic adenocarcinomas to determine new candidate genes that can potentially be used as markers of the disease. The characteristic desmoplastic stromal reaction of pancreatic adenocar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b7361cdaf88752f5acd651b2f2fb47
http://hdl.handle.net/11562/302842
http://hdl.handle.net/11562/302842