Výsledky vyhledávání - "Kerry P. Mahon"

Cyanine dye conjugates as probes for live cell imaging

Autor: Kelly M. Stewart, Kerry P. Mahon, Shana O. Kelley, Jay R. Carreon, Stephanie Shin

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 17:5182-5185

A series of fluorescent compounds suitable for live cell imaging is described. Functionalized forms of four different asymmetric cyanine dyes are reported that are amenable to peptide conjugation. The photophysical properties of the modified dyes and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8694d4a7e60cf431c61a09fae42b3dad
https://doi.org/10.1016/j.bmcl.2007.06.097

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Tunable DNA Cleavage by Intercalating Peptidoconjugates

Autor: Marc D. Roy, Jessica L. Rouge, Erin G. Prestwich, Shana O. Kelley, Kerry P. Mahon, Jay R. Carreon, Stephanie Shin

Publikováno v: ChemBioChem. 7:766-773

The properties of a novel family of peptide-based DNA-cleavage agents are described. Examination of the DNA-cleavage activities of a systematic series of peptide-intercalator conjugates revealed trends that show a strong dependence on peptide sequenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2299cd333e1d1b96debb39c4f017a47e
https://doi.org/10.1002/cbic.200500484

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Thiazole Orange−Peptide Conjugates: Sensitivity of DNA Binding to Chemical Structure

Autor: Kerry P. Mahon, Shana O. Kelley, Jay R. Carreon

Publikováno v: Organic Letters. 6:517-519

[structure: see text] Derivatives of the highly fluorescent and DNA-binding dye thiazole orange (TO) are described that feature appended peptides. Functionalization of TO can be achieved at either of the endocyclic nitrogens, and the photophysical pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cca8219a5336419d2da1f4dc24088c6
https://doi.org/10.1021/ol0362818

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Deconvolution of the cellular oxidative stress response with organelle-specific Peptide conjugates

Autor: Marc D. Roy, Derek Blair, Kelly M. Stewart, Thomas C. Chiles, Kerry P. Mahon, Shana O. Kelley, Terra B. Potocky

Publikováno v: Chemistrybiology. 14(8)

SummaryOxidative stress is a deleterious force that must be combated relentlessly by aerobic organisms and is known to underlie many human diseases including atherosclerosis, Parkinson's disease, and Alzheimer's disease. Information available about t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057d088f21c3abfd9c26ff8abef63c53
https://pubmed.ncbi.nlm.nih.gov/17719486

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