Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kerry L. Homer"'
Autor:
Janet C. Wanstall, Kerry L. Homer
Publikováno v:
British Journal of Pharmacology. 137:1071-1081
1. Inhibition of rat platelet aggregation by the nitric oxide (NO) donor MAHMA NONOate (Z-1-N-methyl-N-[6-(N-methylammoniohexyl)amino]diazen-1-ium-1,2-diolate) was investigated. The aims were to compare its anti-aggregatory effect with vasorelaxation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d86fc9372b387a4fdd273f250982e43
https://doi.org/10.1038/sj.bjp.0704971
https://doi.org/10.1038/sj.bjp.0704971
Autor:
Janet C. Wanstall, Kerry L. Homer
Publikováno v:
British Journal of Pharmacology. 131:673-682
In rat pulmonary artery pre-contracted with phenylephrine, the mechanisms of relaxation to the nitric oxide (NO) donor, spermine NONOate, were investigated. Responses to spermine NONOate were only partially blocked by the soluble guanylate cyclase in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::029874d41e15eb0fb833ba86f6189eba
https://doi.org/10.1038/sj.bjp.0703613
https://doi.org/10.1038/sj.bjp.0703613
Publikováno v:
Current vascular pharmacology. 3(1)
In the vasculature it is well established that cGMP is involved in the relaxant response to nitric oxide (NO) and NO donors. However, there is an increasing evidence that alternative/additional pathways that are cGMP-independent may also exist. A key
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2af479ee0a2ee054374e4028ba61f17
https://pubmed.ncbi.nlm.nih.gov/15638781
https://pubmed.ncbi.nlm.nih.gov/15638781
Autor:
Kerry L. Homer, Janet C. Wanstall
Publikováno v:
European journal of pharmacology. 482(1-3)
The platelet inhibitory effects of the nitric oxide (NO) donor drug MAHMA NONOate ((Z-1-[N-methyl-N-[6-(N-methylammoniohexyl)amino]]diazen-1-ium-1,2-diolate) were examined in anaesthetised rats and compared with those of S-nitrosoglutathione (GSNO; a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7b31e5b7945a3d9c419b4321ccf93f
https://pubmed.ncbi.nlm.nih.gov/14660031
https://pubmed.ncbi.nlm.nih.gov/14660031
Publikováno v:
The Journal of pharmacy and pharmacology. 51(2)
ODQ, (1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one, an inhibitor of soluble guanylate cyclase) inhibits vasorelaxant responses to nitric oxide (NO)-donor drugs, but the extent of the inhibition varies depending on the NO donor studied. The purpose of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd67a9085cf281335bfc6a5f29da4c1f
https://pubmed.ncbi.nlm.nih.gov/10217311
https://pubmed.ncbi.nlm.nih.gov/10217311
Autor:
Janet C. Wanstall, Kerry L. Homer
Publikováno v:
European journal of pharmacology. 356(1)
The pulmonary vasorelaxant properties of two NONOates (diazeniumdiolates) were examined because this novel group of nitric oxide (NO) donors may be useful in pulmonary hypertension. MAHMA NONOate ((Z)-1-?N-Methyl-N-[6-(N-methylammoniohexyl)amino]? di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b55ecdd1f0136bf40c03382a714b72db
https://pubmed.ncbi.nlm.nih.gov/9761423
https://pubmed.ncbi.nlm.nih.gov/9761423