Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Kerry L Burnstein"'
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0287126 (2023)
Androgen deprivation therapy (ADT) is the standard of care for high risk and advanced prostate cancer; however, disease progression from androgen-dependent prostate cancer (ADPC) to lethal and incurable castration-resistant prostate cancer (CRPC) and
Externí odkaz:
https://doaj.org/article/dcf70f64566a4e93901e812ee8157e56
Autor:
Fiorella Magani, Eric R Bray, Maria J Martinez, Ning Zhao, Valeria A Copello, Laine Heidman, Stephanie O Peacock, David J Wiley, Gennaro D'Urso, Kerry L Burnstein
Publikováno v:
Molecular Systems Biology, Vol 14, Iss 8, Pp 1-15 (2018)
Abstract Identifying critical pathways governing disease progression is essential for accurate prognosis and effective therapy. We developed a broadly applicable and novel systems‐level gene discovery strategy. This approach focused on constitutive
Externí odkaz:
https://doaj.org/article/e1b727fc25104d4baa5a654efb317164
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52106 (2012)
MicroRNAs (miRs) are small, endogenous, non-coding RNAs that regulate the stability and/or translation of complementary mRNA targets. MiRs have emerged not only as critical modulators of normal physiologic processes, but their deregulation may signif
Externí odkaz:
https://doaj.org/article/f83917b960df49c0b44283560f0b1877
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 115:511-517
In vivo optical imaging systems are essential to track disease progression and evaluate therapeutic efficacy in animal studies. However, current approaches are limited by their inability to accurately capture 3-dimensional (3-D) image information. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af2418c7df298b0268187e9199a5073d
https://doi.org/10.1016/j.ijrobp.2022.07.1832
https://doi.org/10.1016/j.ijrobp.2022.07.1832
Autor:
Alan Pollack, Kerry L. Burnstein, Sakhi Philip, Zhaomei Mu, Mohammed M. Shareef, Radka Stoyanova, Thirupandiyur S. Udayakumar
(A) LNCaP cells {plus minus} AD were treated with edelfosine (10 µM) and the cells were harvested after 3, 6 and 18 h time points. Cell lysates were examined by Western blotting for p-AKT and total AKT. (B) ARv7 expression in 22RV1 cells. Cells were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ccdd128948f4af950a12dba5cb428b
https://doi.org/10.1158/1535-7163.22503697.v1
https://doi.org/10.1158/1535-7163.22503697.v1
PDF file - 151K, Assessment of phospho-AKT and total AKT in VCaP xenografts treated with combined androgen-deprivation therapy (castration) and ganitumab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f3e14b2a19dfe7b334f074e29a812e
https://doi.org/10.1158/1535-7163.22497694.v1
https://doi.org/10.1158/1535-7163.22497694.v1
Supplementary Figure from Exploiting Dependence of Castration-Resistant Prostate Cancer on the Arginine Vasopressin Signaling Axis by Repurposing Vaptans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::829f899eb62fe1b0d6cc19014674938a
https://doi.org/10.1158/1541-7786.22528064
https://doi.org/10.1158/1541-7786.22528064
Autor:
Kerry L. Burnstein, Jonathan R. Weitz, Rolando Lyles, Pablo S. Magani, Ann M. Greene, Maria J. Martinez, Meghan A. Rice, Stephanie O. Peacock, Fiorella Magani
Supplemental Figure 1: Expression of Vav3 DH domain inhibits the growth of AR-expressing cells only, and does not decrease total levels of FL-AR, AR-V7, Vav3 or Vav2. Supplemental Figure 2: Disruption of coactivator interactions with FL-AR or AR-V7 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a8842e0c6834f001fe7db2ea8b7bbd
https://doi.org/10.1158/1541-7786.22511994.v1
https://doi.org/10.1158/1541-7786.22511994.v1
PDF file - 151K, Evaluation of AR and ARΔLBD in androgen-dependent VCaP xenografts, castration-resistant VCaP xenografts, and castration-resistant 22Rv1 xenografts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ee46832127bf8a62561644c9784ce1b
https://doi.org/10.1158/1535-7163.22497697
https://doi.org/10.1158/1535-7163.22497697