Zobrazeno 1 - 10 of 87 pro vyhledávání: '"Kerry L, Tucker"'
1
Akademický článek
Electrophysiological phenotyping of left ventricular noncompaction cardiomyopathy in pediatric populations: A systematic review
Autor: Lindsey A. Fitzsimons, Delanie M. Kneeland‐Barber, Gracie C. Hannigan, David A. Karpe, Lyman Wu, Michael Colon, Jess Randall, Kerry L. Tucker
Publikováno v: Physiological Reports, Vol 12, Iss 9, Pp n/a-n/a (2024)
Abstract Left ventricular noncompaction cardiomyopathy (LVNC) is a structural heart defect that has been associated with generation of arrhythmias in the population and is a cause of sudden cardiac death with severe systolic dysfunction and fatal arr
Externí odkaz: https://doaj.org/article/5bb4d790dd4a40cc971a23cfd5e6bbd3
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2
Akademický článek
Hedgehog Morphogens Act as Growth Factors Critical to Pre- and Postnatal Cardiac Development and Maturation: How Primary Cilia Mediate Their Signal Transduction
Autor: Lindsey A. Fitzsimons, Victoria L. Brewer, Kerry L. Tucker
Publikováno v: Cells, Vol 11, Iss 12, p 1879 (2022)
Primary cilia are crucial for normal cardiac organogenesis via the formation of cyto-architectural, anatomical, and physiological boundaries in the developing heart and outflow tract. These tiny, plasma membrane-bound organelles function in a sensory
Externí odkaz: https://doaj.org/article/0c9f8630ac5346778bc2203137e1c703
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4
Akademický článek
Targeted Depletion of Primary Cilia in Dopaminoceptive Neurons in a Preclinical Mouse Model of Huntington’s Disease
Autor: Rasem Mustafa, Grzegorz Kreiner, Katarzyna Kamińska, Amelia-Elise J. Wood, Joachim Kirsch, Kerry L. Tucker, Rosanna Parlato
Publikováno v: Frontiers in Cellular Neuroscience, Vol 13 (2019)
Multiple pathomechanisms triggered by mutant Huntingtin (mHTT) underlie progressive degeneration of dopaminoceptive striatal neurons in Huntington’s disease (HD). The primary cilium is a membrane compartment that functions as a hub for various path
Externí odkaz: https://doaj.org/article/3395b7c3450444e69c5d4d9c577c1e55
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5
Akademický článek
Targeted Ablation of Primary Cilia in Differentiated Dopaminergic Neurons Reduces Striatal Dopamine and Responsiveness to Metabolic Stress
Autor: Rasem Mustafa, Chahinaz Rawas, Nadja Mannal, Grzegorz Kreiner, Björn Spittau, Katarzyna Kamińska, Rüstem Yilmaz, Christina Pötschke, Joachim Kirsch, Birgit Liss, Kerry L. Tucker, Rosanna Parlato
Publikováno v: Antioxidants, Vol 10, Iss 8, p 1284 (2021)
Primary cilia (PC) are microtubule-based protrusions of the cell membrane transducing molecular signals during brain development. Here, we report that PC are required for maintenance of Substantia nigra (SN) dopaminergic (DA) neurons highly vulnerabl
Externí odkaz: https://doaj.org/article/d98629c1c86f4fd5804825c4701b9a09
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6
A cell-autonomous role for primary cilia in long-range commissural axon guidance
Autor: Alexandre Dumoulin, Nicole H. Wilson, Kerry L. Tucker, Esther T. Stoeckli
SummaryCiliopathies are characterized by the absence or dysfunction of primary cilia. Despite the fact that cognitive impairments are a common feature of ciliopathies, how cilia dysfunction affects neuronal development has not been characterized in d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::92520ca75e2c5a8bf5ebbbe68b6f3a9e
https://doi.org/10.1101/2022.08.15.503894
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7
Akademický článek
Positional Cloning of cobblestone, a Mouse Mutant Showing Major Defects in Brain Development, Identifies Ift88 as a Candidate Gene
Autor: Marc A. Willaredt, Valentin Evsyukov, Kerry L. Tucker
Publikováno v: Impulse: The Premier Undergraduate Neuroscience Journal, Pp 1-14 (2010)
The ENU-induced cobblestone (cbs) mouse mutant exhibits severe defects in fore- and midbrain development. Via genomic mapping, the causative mutation for the cbs-phenotype has previously been located on chromosome 14 in the proximity of the gene Ift8
Externí odkaz: https://doaj.org/article/76fe3569e7d54f078f9c8ea9f471ea78
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9
Targeted Ablation of Primary Cilia in Differentiated Dopaminergic Neurons Reduces Striatal Dopamine and Responsiveness to Metabolic Stress
Autor: Grzegorz Kreiner, Nadja Mannal, Rasem Mustafa, Björn Spittau, Joachim Kirsch, Kerry L. Tucker, Rosanna Parlato, Rüstem Yilmaz, Christina Pötschke, Chahinaz Rawas, Katarzyna Kamińska, Birgit Liss
Publikováno v: Antioxidants, Vol 10, Iss 1284, p 1284 (2021)
Antioxidants
Volume 10
Issue 8
Primary cilia (PC) are microtubule-based protrusions of the cell membrane transducing molecular signals during brain development. Here, we report that PC are required for maintenance of Substantia nigra (SN) dopaminergic (DA) neurons highly vulnerabl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5863d36a074bf945b46f46648ac28c89
https://pub.uni-bielefeld.de/record/2957243
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10
Akademický článek
Region-specific integration of embryonic stem cell-derived neuronal precursors into a pre-existing neuronal circuit.
Autor: Franziska Neuser, Martin Polack, Christine Annaheim, Kerry L Tucker, Martin Korte
Publikováno v: PLoS ONE, Vol 8, Iss 6, p e66497 (2013)
Enduring reorganization is accepted as a fundamental process of adult neural plasticity. The most dramatic example of this reorganization is the birth and continuously occurring incorporation of new neurons into the pre-existing network of the adult
Externí odkaz: https://doaj.org/article/33a1f0bcd3414876aa1b3e453a56885b
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