Výsledky vyhledávání - "Kerry Goldin"

Akademický článek

Low level of tonic interferon signalling is associated with enhanced susceptibility to SARS-CoV-2 variants of concern in human lung organoids

Autor: Meaghan Flagg, Kerry Goldin, Lizzette Pérez-Pérez, Manmeet Singh, Brandi N. Williamson, Nathanael Pruett, Chuong D. Hoang, Emmie de Wit

Publikováno v: Emerging Microbes and Infections, Vol 12, Iss 2 (2023)

There is tremendous heterogeneity in the severity of COVID-19 disease in the human population, and the mechanisms governing the development of severe disease remain incompletely understood. The emergence of SARS-CoV-2 variants of concern (VOC) Delta

Externí odkaz: https://doaj.org/article/ec540c177e954033983095d97fb37a3b

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Akademický článek

ChAdOx1 NiV vaccination protects against lethal Nipah Bangladesh virus infection in African green monkeys

Autor: Neeltje van Doremalen, Victoria A. Avanzato, Kerry Goldin, Friederike Feldmann, Jonathan E. Schulz, Elaine Haddock, Atsushi Okumura, Jamie Lovaglio, Patrick W. Hanley, Kathleen Cordova, Greg Saturday, Emmie de Wit, Teresa Lambe, Sarah C. Gilbert, Vincent J. Munster

Publikováno v: npj Vaccines, Vol 7, Iss 1, Pp 1-8 (2022)

Abstract Nipah virus (NiV) is a highly pathogenic and re-emerging virus, which causes sporadic but severe infections in humans. Currently, no vaccines against NiV have been approved. We previously showed that ChAdOx1 NiV provides full protection agai

Externí odkaz: https://doaj.org/article/83a42009c7d8459eafa1e723eb0e5001

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Akademický článek

Distinct VSV-based Nipah virus vaccines expressing either glycoprotein G or fusion protein F provide homologous and heterologous protection in a nonhuman primate modelResearch in context

Autor: Emmie de Wit, Friederike Feldmann, Jacqueline Cronin, Kerry Goldin, Reinaldo Mercado-Hernandez, Brandi N. Williamson, Kimberly Meade-White, Atsushi Okumura, Julie Callison, Sarah Weatherman, Rebecca Rosenke, Victoria A. Avanzato, Jamie Lovaglio, Dana P. Scott, Andrea Marzi, Heinz Feldmann

Publikováno v: EBioMedicine, Vol 87, Iss , Pp 104405- (2023)

Summary: Background: Nipah virus (NiV) causes recurrent outbreaks of lethal respiratory and neurological disease in Southeast Asia. The World Health Organization considers the development of an effective vaccine against NiV a priority. Methods: We pr

Externí odkaz: https://doaj.org/article/dfff7aaf39d542d6855906a23c3664cd

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