Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Kerry Geiler-Samerotte"'
Autor:
Kara Schmidlin, Sam Apodaca, Daphne Newell, Alexander Sastokas, Grant Kinsler, Kerry Geiler-Samerotte
Publikováno v:
eLife, Vol 13 (2024)
There is growing interest in designing multidrug therapies that leverage tradeoffs to combat resistance. Tradeoffs are common in evolution and occur when, for example, resistance to one drug results in sensitivity to another. Major questions remain a
Externí odkaz:
https://doaj.org/article/288a132111a747fd8971074734a3f8e1
Autor:
Adele Crane, Joy Abaidoo, Gabriella Beltran, Danielle Fry, Colleen Furey, Noe Green, Ravneet Johal, Bruno La Rosa, Catalina Lopez Jimenez, Linh Luong, Garett Maag, Jade Porche, Lauren Reyes, Aspen Robinson, Samantha Sabbara, Lucia Soto Herrera, Angelica Urquidez Negrete, Pauline Wilson, Kerry Geiler-Samerotte, Susanne P. Pfeifer
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 9, Pp 2975-2979 (2020)
Phages infecting bacteria of the genus Staphylococcus play an important role in their host’s ecology and evolution. On one hand, horizontal gene transfer from phage can encourage the rapid adaptation of pathogenic Staphylococcus enabling them to es
Externí odkaz:
https://doaj.org/article/154a7f46e85e4aeaa99bfef5561dca68
Publikováno v:
eLife, Vol 9 (2020)
Building a genotype-phenotype-fitness map of adaptation is a central goal in evolutionary biology. It is difficult even when adaptive mutations are known because it is hard to enumerate which phenotypes make these mutations adaptive. We address this
Externí odkaz:
https://doaj.org/article/14e9f3caaa7e4aa3a620e28a7076eb2f
Autor:
Grant Kinsler, Kara Schmidlin, Daphne Newell, Rachel Eder, Sam Apodaca, Grace Lam, Dmitri Petrov, Kerry Geiler-Samerotte
Publikováno v:
Journal of Molecular Evolution.
The phrase “survival of the fittest” has become an iconic descriptor of how natural selection works. And yet, precisely measuring fitness, even for single-celled microbial populations growing in controlled laboratory conditions, remains a challen
Publikováno v:
Journal of Molecular Evolution.
Despite the tremendous diversity and complexity of life forms, there are certain forms of life that are never observed. Organisms like angels might not emerge because of developmental constraint, or because they have low fitness in any environment ye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ee9e7551b204f58ffda5e77437be39b
https://doi.org/10.1101/2023.05.12.540583
https://doi.org/10.1101/2023.05.12.540583
Yeasts are naturally diverse, genetically tractable, and easy to grow in a myriad of experimental conditions such that researchers have the ability to investigate any number of genotypes, strains, environments, or the interaction thereof. However, st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85df20cf0d27424982f9c676efd76ec6
https://doi.org/10.1101/2022.09.12.507686
https://doi.org/10.1101/2022.09.12.507686
Publikováno v:
Journal of Molecular Evolution
Evolution has led to a great diversity that ranges from elegant simplicity to ornate complexity. Many complex features are often assumed to be more functional or adaptive than their simpler alternatives. However, in 1999, Arlin Stolzfus published a p
Autor:
Bruno La Rosa, Garett Maag, Pauline Wilson, Adele Crane, Lauren Reyes, Linh B. Luong, Lucia Soto Herrera, Gabriella Beltran, Noe Green, Danielle Fry, Catalina Lopez Jimenez, Kerry Geiler-Samerotte, Joy Abaidoo, Angelica Urquidez Negrete, Colleen Furey, Jade Porche, Susanne P. Pfeifer, Samantha Sabbara, Aspen Robinson, Ravneet Johal
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 9, Pp 2975-2979 (2020)
Phages infecting bacteria of the genus Staphylococcus play an important role in their host’s ecology and evolution. On one hand, horizontal gene transfer from phage can encourage the rapid adaptation of pathogenic Staphylococcus enabling them to es
Autor:
David Posada, Belinda S. W. Chang, Jody Hey, Michelle M. Meyer, Aaron David Goldman, Kerry Geiler-Samerotte, David A. Liberles, Betul Kacar, Andrew Storfer, William J. Murphy
Publikováno v:
J Mol Evol
A collection of the editors of Journal of Molecular Evolution have gotten together to pose a set of key challenges and future directions for the field of molecular evolution. Topics include challenges and new directions in prebiotic chemistry and the