Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kerry F White"'
Autor:
Marisa O Peluso, Veronica T Campbell, Joseph A Harari, Thomas T Tibbitts, Jennifer L Proctor, Nigel Whitebread, James M Conley, Kerry F White, Jeffery L Kutok, Margaret A Read, Karen McGovern, Kerrie L Faia
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90534 (2014)
A requisite step for canonical Hedgehog (Hh) pathway activation by Sonic Hedgehog (Shh) ligand is accumulation of Smoothened (Smo) to the primary cilium (PC). Activation of the Hh pathway has been implicated in a broad range of cancers, and several S
Externí odkaz:
https://doaj.org/article/b3435ef7823e4fa0b69c0b4bca9c80e8
Autor:
Daniel L. Aldridge, Devapregasan Moodley, Jeongho Park, Anthony T. Phan, Matthew Rausch, Kerry F. White, Yue Ren, Karin Golin, Enrico Radaelli, Ross Kedl, Pamela M. Holland, Jonathan Hill, Christopher A. Hunter
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT Mice that lack the genes for IL-27, or the IL-27 receptor, and infected with Toxoplasma gondii develop T cell-mediated pathology. Here, studies were performed to determine the impact of endogenous IL-27 on the immune response to T. gondii in
Externí odkaz:
https://doaj.org/article/9c9b0287df4046c6ad8d1fbed541ca45
Autor:
Turan Aghayev, Aleksandra M. Mazitova, Jennifer R. Fang, Iuliia O. Peshkova, Matthew Rausch, Manhsin Hung, Kerry F. White, Ricard Masia, Elizaveta K. Titerina, Aliia R. Fatkhullina, Isabelle Cousineau, Simon Turcotte, Dmitry Zhigarev, Anastasiia Marchenko, Svetlana Khoziainova, Petr Makhov, Yin Fei Tan, Andrew V. Kossenkov, David L. Wiest, John Stagg, Xin Wei Wang, Kerry S. Campbell, Amiran K. Dzutsev, Giorgio Trinchieri, Jonathan A. Hill, Sergei I. Grivennikov, Ekaterina K. Koltsova
Publikováno v:
Cancer Discov
Although inflammatory mechanisms driving hepatocellular carcinoma (HCC) have been proposed, the regulators of anticancer immunity in HCC remain poorly understood. We found that IL27 receptor (IL27R) signaling promotes HCC development in vivo. High IL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b42bb7609baab1cde84e56f1ce8cef
https://doi.org/10.1158/2159-8290.cd-20-1628
https://doi.org/10.1158/2159-8290.cd-20-1628
Autor:
Ekaterina K. Koltsova, Sergei I. Grivennikov, Jonathan A. Hill, Giorgio Trinchieri, Amiran K. Dzutsev, Kerry S. Campbell, Xin Wei Wang, John Stagg, David L. Wiest, Andrew V. Kossenkov, Yin Fei Tan, Petr Makhov, Svetlana Khoziainova, Anastasiia Marchenko, Dmitry Zhigarev, Simon Turcotte, Isabelle Cousineau, Aliia R. Fatkhullina, Elizaveta K. Titerina, Ricard Masia, Kerry F. White, Manhsin Hung, Matthew Rausch, Iuliia O. Peshkova, Jennifer R. Fang, Aleksandra M. Mazitova, Turan Aghayev
Although inflammatory mechanisms driving hepatocellular carcinoma (HCC) have been proposed, the regulators of anticancer immunity in HCC remain poorly understood. We found that IL27 receptor (IL27R) signaling promotes HCC development in vivo. High IL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0488eaf43d501ff25edc4bae4c3d2bba
https://doi.org/10.1158/2159-8290.c.6549593.v1
https://doi.org/10.1158/2159-8290.c.6549593.v1
Autor:
Ekaterina K. Koltsova, Sergei I. Grivennikov, Jonathan A. Hill, Giorgio Trinchieri, Amiran K. Dzutsev, Kerry S. Campbell, Xin Wei Wang, John Stagg, David L. Wiest, Andrew V. Kossenkov, Yin Fei Tan, Petr Makhov, Svetlana Khoziainova, Anastasiia Marchenko, Dmitry Zhigarev, Simon Turcotte, Isabelle Cousineau, Aliia R. Fatkhullina, Elizaveta K. Titerina, Ricard Masia, Kerry F. White, Manhsin Hung, Matthew Rausch, Iuliia O. Peshkova, Jennifer R. Fang, Aleksandra M. Mazitova, Turan Aghayev
Supplementary Data from IL27 Signaling Serves as an Immunologic Checkpoint for Innate Cytotoxic Cells to Promote Hepatocellular Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6efd13a825c7040a930bdf2b3cbab6b2
https://doi.org/10.1158/2159-8290.22541261.v1
https://doi.org/10.1158/2159-8290.22541261.v1
Autor:
Jonathan A. Hill, Kerry F. White, Matthew Rausch, Jou-Ku Chung, Amita Patnaik, Aung Naing, Daniel Morgensztern, Charlene M. Mantia, Nizar M. Tannir, Lon S. Smith, Beth Bowers, Alex Alika, Lauren C. Harshman, Benjamin H. Lee
Publikováno v:
Cancer Research. 82:1137-1137
SRF388 is a first-in-class, anti-IL-27 antibody developed to enhance immune responses within the tumor microenvironment. Preclinical studies have demonstrated that IL-27 pathway blockade can inhibit tumor growth in mouse models of liver cancer and lu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eee319d2ec74f4dc41ed479af5980d8a
https://doi.org/10.1158/1538-7445.am2022-1137
https://doi.org/10.1158/1538-7445.am2022-1137
Autor:
Katarzyna Składanowska, Yehudi Bloch, Jamie Strand, Kerry F. White, Jing Hua, Daniel Aldridge, Martin Welin, Derek T. Logan, Arne Soete, Romain Merceron, Casey Murphy, Mathias Provost, J. Fernando Bazan, Christopher A. Hunter, Jonathan A. Hill, Savvas N. Savvides
Publikováno v:
CELL REPORTS
Cell reports 41(3), 111490 (2022). doi:10.1016/j.celrep.2022.111490
Cell Reports 41, 111490 (2022)
Cell reports 41(3), 111490 (2022). doi:10.1016/j.celrep.2022.111490
Cell Reports 41, 111490 (2022)
Cell reports 41(3), 111490 (2022). doi:10.1016/j.celrep.2022.111490
Interleukin-27 (IL-27) uniquely assembles p28 and EBI3 subunits to a heterodimeric cytokine that signals via IL-27Rα and gp130. To provide the structural framework for receptor
Interleukin-27 (IL-27) uniquely assembles p28 and EBI3 subunits to a heterodimeric cytokine that signals via IL-27Rα and gp130. To provide the structural framework for receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b3a2ed20002fe74643654f096aa99a4