Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Kerry E. Barber"'
Autor:
G. Reza Jalali, Christine J. Harrison, Jonathan C. Strefford, Sarah Wright, Rachel L. Harris, Kerry E. Barber, Anthony V. Moorman, Mike Griffiths, Hazel M. Robinson, Zoë J. Broadfield, Louise Harewood, Adam R. M. Stewart, Fiona M. Ross, M Martineau, Kan L. Cheung
Publikováno v:
British Journal of Haematology. 129:520-530
Summary Interphase fluorescence in situ hybridization (iFISH) was used independently to reveal chromosomal abnormalities of prognostic importance in a large, consecutive series of children (n = 2367) with acute lymphoblastic leukaemia (ALL). The fusi
Autor:
Rachel L. Harris, G. Reza Jalali, Frank Hill, Susan M. Richards, I. Jill Durrant, Ajay Vora, Christine J. Harrison, Tim O B Eden, Anthony H. Goldstone, Hazel M. Robinson, Zoë J. Broadfield, Kerry E. Barber, Sally E. Kinsey, M Martineau, Brenda Gibson, Ian Hann, Ian M. Franklin, Kan L. Cheung, Chris Mitchell, Anthony V. Moorman, John S. Lilleyman
Publikováno v:
British Journal of Haematology. 125:552-559
This study of children and adults with acute lymphoblastic leukaemia (ALL) is the largest series of patients with hypodiploidy (
Autor:
AS Gabriel, Sarah L. Wright, Christine J. Harrison, Zoe J. Konn, Claire Schwab, Amy Erhorn, Halima A Al-Shehhi, Kerry E. Barber, Anthony V. Moorman
Publikováno v:
Genes, chromosomescancer. 52(2)
ETV6-RUNX1 fusion [t(12;21)(p13;q22)] occurs in 25% of childhood B-cell precursor acute lymphoblastic leukemia (BCPALL) and is associated with a favorable outcome. Additional abnormalities involving der(21)t(12;21) and nonrearranged chromosome 12 are
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 538
Cytogenetics is integral to the diagnosis of childhood leukaemia, particularly in relation to the risk stratification of patients for treatment. Fluorescence in situ hybridization (FISH) has become an important complementary technique, expanding chro
Publikováno v:
Leukemia ISBN: 9781588299895
Cytogenetics is integral to the diagnosis of childhood leukaemia, particularly in relation to the risk stratification of patients for treatment. Fluorescence in situ hybridization (FISH) has become an important complementary technique, expanding chro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7f8c5014c96f3b516d625c3090ebdd7
https://doi.org/10.1007/978-1-59745-418-6_3
https://doi.org/10.1007/978-1-59745-418-6_3
Autor:
Jonathan C. Strefford, Nick Bown, Sarina Sulong, Helen Parker, Sarah L. Wright, Anthony V. Moorman, Marian Case, Simon Bailey, Zoe J. Konn, Lynne Minto, Christine J. Harrison, Julie Irving, Adam R. M. Stewart, Andrew G. Hall, Kerry E. Barber
Publikováno v:
Blood. 113(1)
Inactivation of the tumor suppressor gene, CDKN2A, can occur by deletion, methylation, or mutation. We assessed the principal mode of inactivation in childhood acute lymphoblastic leukemia (ALL) and frequency in biologically relevant subgroups. Mutat
Autor:
Christine J. Harrison, Jonathan C. Strefford, Kerry E. Barber, Zoe J. Konn, Andrew G. Hall, Adam R. M. Stewart, Helen Parker, Fiona M. Ross, Sarah L. Wright, Michael J. Griffiths, Julie Irving, Marian Case, Qian An, Anthony V. Moorman, Teresa Davies
Publikováno v:
Genes, chromosomescancer. 47(12)
The ETV6-RUNX1 fusion is the molecular consequence of the t(12;21)(p13;q22) seen in approximately 25% of children with acute lymphoblastic leukemia (ALL). Studies have shown that the fusion alone is insufficient for the initiation of leukemia; additi
Autor:
Kerry E. Barber, Zoë J. Broadfield, Anthony V. Moorman, Adam R. M. Stewart, Jonathan C. Strefford, Sarah L. Wright, M Martineau, Christine J. Harrison
Publikováno v:
Genes, chromosomescancer. 46(5)
The t(1; 19)(q23;p 13.3) is one of the most common chromosomal abnormalities in B-cell precursor acute lymphoblastic leukemia (BCP-ALL) and usually gives rise to the TCF3-PBXI fusion gene. Additional rare, and sometimes cytogenetically cryptic, trans
Autor:
Anthony V. Moorman, Hazel M. Robinson, F W van Delft, Helen Worley, Christine J. Harrison, Sarah Wright, Jonathan C. Strefford, G Bettney, Fiona M. Ross, Vaskar Saha, Teresa Davies, Adam R. M. Stewart, Sandra Hing, Polly Talley, Mike Griffiths, Mark G. Atherton, Kerry E. Barber
Publikováno v:
Oncogene. 26(29)
Chromosomal abnormalities are important for the classification and risk stratification of patients with acute lymphoblastic leukemia (ALL). However, approximately 30% of childhood and 50% of adult patients lack abnormalities with clinical relevance.
Autor:
M Martineau, John S. Lilleyman, Sue Richards, Kan Luk Cheung, Fiona M. Ross, Christine J. Harrison, Zoë J. Broadfield, Anthony V. Moorman, G. Reza Jalali, Kerry E. Barber, Hazel M. Robinson
Publikováno v:
Genes, chromosomes and cancer. 43(1)
This study was undertaken in order to compare the interphase and metaphase cytogenetics of 28 patients with ETV6/RUNX1 positive acute lymphoblastic leukemia, at diagnosis and relapse. The median time to relapse was 26 months. The significant fusion p