Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Kerry Deutsch"'
Autor:
Raghavee Venkatramanan, Kerry Deutsch, Inah Golez, Pallavi Shroff, Spencer Seale, Brendan Ralph, Sally. Dow, Evan Anderson, Saman Tahir, Anjali Malge, Corey Braastad, Steven Anderson
Publikováno v:
Cancer Research. 79:1679-1679
Colorectal cancer (CRC) is one of the major causes of global mortality. Recent clinical advances in T cell therapy using antibodies that block inhibitory T cell signals have been transforming cancer therapy. Studies show that somatic mutations in pro
Autor:
William J. Catalona, Bo Johanneson, Kathleen Herkommer, Brian T. Helfand, Daniel J. Schaid, Henrik Grönberg, Jianfen Xu, Johanna Schleutker, James M. Farnham, Donghui Kan, Ingrid Oakley-Girvan, Antoine Valeri, Steve Edwards, Teuvo L.J. Tammela, Lingyi Lu, Chih-Lin Hsieh, Josef Hoegel, Ethan M. Lange, Olivier Cussenot, John D. Carpten, Lovise Maehle, Cheryl D. Cropp, William B. Isaacs, Geraldine Cancel-Tassin, Gianluca Severi, Sarah D. Isaacs, Elaine A. Ostrander, Dallas R. English, John L. Hopper, Douglas T. Easton, Joan E. Bailey-Wilson, Shannon K. McDonnell, Stephen N. Thibodeau, Fredrik Wiklund, Kerry Deutsch, Liesel M. FitzGerald, Alice S. Whittemore, Kathleen A. Cooney, Christiane Maier, Claire L. Simpson, Laura McIntosh, Lisa A. Cannon-Albright, Isaac J. Powell, Pål Møller, Janet L. Stanford, Scott J. Hebbring, Daniela Seminara, Patrick C. Walsh, William D. Foulkes, Michelle Guy, Monica Emanuelsson, Michael D. Badzioch, Walther Vogel, Nicola J. Camp, Ros Eeles, Graham G. Giles, Kathleen E. Wiley, S. Lilly Zheng
Publikováno v:
The Prostate. 72:410-426
BACKGROUND In spite of intensive efforts, understanding of the genetic aspects of familial prostate cancer (PC) remains largely incomplete. In a previous microsatellite-based linkage scan of 1,233 PC families, we identified suggestive evidence for li
Autor:
Spencer Chee, Briana Hudson, Fang Yin Lo, Vickie Satele, Kerry Deutsch, Steve Anderson, Elliot Swanson, Anup Madan, Sally Dow, Evan Anderson, Tuuli Saloranta, Inah Golez, Saman Tahir, Raghavee Venkatramanan, Kimberly Kruse
Publikováno v:
Cancer Research. 78:3418-3418
Colorectal cancer (CRC) is one of the major causes of global cancer mortality. Until recently, KRAS has been the only predictive biomarker for anti-EGFR therapy for metastatic CRC, and yet predicting prognosis in clinical practice is still poor. Ther
Autor:
Timothy J. Yeatman, Anup Madan, Steven Anderson, Tuuli Saloranta, Kerry Deutsch, Claire Olson, Fang Yin Lo, Inah Golez
Publikováno v:
Cancer Research. 78:5379-5379
Colorectal cancer (CRC) is the third most common type of cancer in the United States. Although chemotherapy, radiation and targeted therapies can improve survival rates, recent studies have shown the potential benefit of immunotherapies to improve ou
Autor:
Kerry Deutsch, Tuuli Saloranta, Mukta Dutta, Steve Anderson, Cara Lord, Vickie Satele, Inah Golez, Anup Madan
Publikováno v:
Cancer Research. 78:3578-3578
Single-cell gene expression analysis has been shown to delineate cellular heterogeneity. Such analyses result in the discovery of genes that identify subtypes of cells, or that mark intermediate states during a biological process. Cellular heterogene
Autor:
Elaine A. Ostrander, Daniel J. Schaid, Shannon K. McDonnell, Kerry Deutsch, Wendy J. Langeberg, Janet L. Stanford, Liesel M. FitzGerald, Laura McIntosh, Erin E. Carlson
Publikováno v:
European Journal of Human Genetics. 18:1141-1147
The search for susceptibility loci in hereditary prostate cancer (HPC) is challenging because of locus and disease heterogeneity. One approach to reduce disease heterogeneity is to stratify families on the basis of the occurrence of multiple cancer t
Autor:
Laura McIntosh, Bo Johanneson, Danielle M. Karyadi, Scott J. Hebbring, Daniel J. Schaid, Shannon K. McDonnell, Miia Suuriniemi, Kerry Deutsch, Liang Wang, Elaine A. Ostrander, Erika M. Kwon, Janet L. Stanford, Stephen N. Thibodeau
Publikováno v:
Human Genetics. 123:65-75
Genetic studies suggest that hereditary prostate cancer is a genetically heterogeneous disease with multiple contributing loci. Studies of high-risk prostate cancer families selected for aggressive disease, analysis of large multigenerational familie
Autor:
Marta Janer, Daniel J. Schaid, Laura McIntosh, Erin E. Carlson, Janet L. Stanford, Miia Suuriniemi, Lee Hood, Danielle M. Karyadi, Elaine A. Ostrander, Shannon K. McDonnell, Kerry Deutsch
Publikováno v:
Human Genetics. 121:729-735
Despite evidence that prostate cancer has a genetic etiology, it has been extremely difficult to confirm genetic linkage results across studies, emphasizing the large extent of genetic heterogeneity associated with this disease. Because prostate canc
Publikováno v:
Computer Methods and Programs in Biomedicine. 85:203-209
RNA interference (RNAi) is a popular and effective method for silencing gene expression. siRNAs should be gene-specific and effective to achieve specific and potent gene silencing. However, most currently available siRNA design programs are web-based
Autor:
Erika M. Kwon, Laura McIntosh, Kerry Deutsch, Marta Janer, Leroy Hood, Danielle M. Friedrichsen-Karyadi, Janet L. Stanford, Bo Johanneson, Elaine A. Ostrander, Lori Iwasaki
Publikováno v:
The Prostate. 67:732-742
BACKGROUND. The Seattle-based PROGRESS study was started in 1995 to ascertain hereditary prostate cancer (HPC) families for studies of genetic susceptibility. Subsequent studies by several research groups, including our own, suggest that HPC is a gen