Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Kerry Combs"'
Autor:
John A. Butera, Weiheng Wang, Joan E. Sabalski, Julie Liu, Lynn Resnick, Kevin D. Parris, Jean-Baptiste Telliez, Kerry Combs, Frank Lovering, Steven J. Kirincich
Publikováno v:
Bioorganic & Medicinal Chemistry. 17:3342-3351
A novel series of inhibitors for mitogen activated protein kinase-activated protein kinase 2 (MK-2) are reported. These squarate based inhibitors were identified via a high-throughput screen. An MK2 co-structure with the starting ligand was obtained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90348df20fa278de0e487146df5bfba2
https://doi.org/10.1016/j.bmc.2009.03.041
https://doi.org/10.1016/j.bmc.2009.03.041
Autor:
Alberto Podjarny, Andre Mitschler, Kerry Combs, Evelyn O. Sibley, Al Sabetta, Erin E. McCann, Anne L. Carrington, Eduardo Howard, Diane R. Sawicki, Janet Sredy, Brenda R. Flam, Michael C. Van Zandt
Publikováno v:
Bioorganic & Medicinal Chemistry. 12:5661-5675
Recent efforts to identify treatments for chronic diabetic complications have resulted in the discovery of a novel series of highly potent and selective (2-arylcarbamoyl-phenoxy)-acetic acid aldose reductase inhibitors. The compound class features a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13db3aac24df5f7e98ec33b604b28785
https://doi.org/10.1016/j.bmc.2004.07.062
https://doi.org/10.1016/j.bmc.2004.07.062