Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kerry B. Hafner"'
Autor:
Katherine M. Dunnington, Zhiming Wang, Edward K. Hill, Thomas R. Zimmerman, Maxine Stoltz, Kerry B. Hafner, Jean T. Barbey, Ming-yi Hu, Gregory C. Williams
Publikováno v:
Journal of Cardiovascular Electrophysiology. 17:352-358
The Impact of Posture on Cardiac Repolarization: More Than Heart Rate? Introduction: The effect of standing on heart rate and QT is well known but its impact on QTc is less clear. Methods: Serial supine and standing 12-lead ECGs (seven pairs each day
Autor:
Kent Letourneau, Daniel E Wagner, Gina L Burgess, Gene L. Colice, Robert J. Dockhorn, Nancy M. Klinger, Kerry B Hafner
Publikováno v:
Annals of Allergy, Asthma & Immunology. 79:85-88
Introduction During the 1970s, scientists suggested that the growing use of chlorofluorocarbons (CFCs) was contributing to depletion of the stratospheric ozone layer with potentially harmful results. A committee on the ozone layer organized the prepa
Autor:
William H. Stewart, Kerry B. Hafner
Publikováno v:
Drug Information Journal. 25:405-409
The trough/peak ratio, the ratio of mean trough effect to mean peak effect, has been recently proposed as a measure for evaluating sustained release formulations of antihypertensive medications. This paper gives a method for constructing exact confid
Autor:
Stephen J. Ruberg, Kerry B. Hafner
Publikováno v:
Journal of biopharmaceutical statistics. 6(3)
In the early stages of traditional drug development, the frequency of dosing (e.g., QD, BID, etc.) is typically determined by the pharmacokinetic properties of a compound. After an appropriate dose frequency is chosen, the magnitude of dose is then e
Autor:
Thomas J. Comstock, James V. Felicetta, Kerry B. Hafner, Neal R. Cutler, Matthew R. Weir, Harry M. Serfer, Gary L. Huber, Glen D. Park
Publikováno v:
American heart journal. 123(4 Pt 1)
This trial was performed to determine the safe and effective dosage range of once daily diltiazem (diltiazem CD) capsules for treatment of essential hypertension. Patients with essential hypertension having supine diastolic blood pressure values grea
Publikováno v:
Journal of the American Statistical Association. 84:797-804
Consideration is given to longitudinal data settings in which an ordinal response variable is observed at two or more visits for each subject in two or more ordered groups with at least moderately large sample sizes (e.g., overall n ≥ 40). Rank mea
Publikováno v:
Statistics in Medicine. 7:471-481
Alternative analysis strategies for the three-period crossover design with two treatments are discussed in this paper. One analysis strategy involves a parametric model that incorporates the effects of interest. To implement this method, one usually