Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Kerry A Millington"'
Autor:
Davinder P S Dosanjh, Mustafa Bakir, Kerry A Millington, Ahmet Soysal, Yasemin Aslan, Serpil Efee, Jonathan J Deeks, Ajit Lalvani
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28754 (2011)
Mycobacterium tuberculosis Region-of-Difference-1 gene products present opportunities for specific diagnosis of M. tuberculosis infection, yet immune responses to only two gene-products, Early Secretory Antigenic Target-6 (ESAT-6) and Culture Filtrat
Externí odkaz:
https://doaj.org/article/8b9b8b2d601c4ee4ae096e5931007071
Autor:
Jeremiah Chikovore, Beate Ringwald, Amon Ashaba Mwiine, Goodman Makanda, Jerry Amoah-Larbi, Kerry A. Millington, Katherine C. Horton
Publikováno v:
BMJ Global Health, Vol 8, Iss 12 (2023)
Externí odkaz:
https://doaj.org/article/3ceb557e700c4fbdb7e1bb63c57663d4
Autor:
Kerry A. Millington
The COVID-19 pandemic has had a tremendous negative impact on economies of most countries around the world. COVID-19 has disrupted the ability of health systems to deliver on essential health services and has also exposed pre-existing vulnerabilities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::033c358a36e74fcc8d69f1e016fd20be
https://doi.org/10.19088/k4d.2021.084
https://doi.org/10.19088/k4d.2021.084
Autor:
Nisha Karnani, Kerry A. Millington, Davinder Dosanjh, Saranya Sridhar, Mustafa Bakir, David W. Connell, Jonathan J Deeks, Ahmet Soysal, Ajit Lalvani
Publikováno v:
Pediatric Infectious Disease Journal. 33:1303-1306
Risk factors associated with Mycobacterium tuberculosis infection were investigated in a prospective cohort of household child tuberculosis contacts. A significantly increased risk of acquiring infection was associated with exposure to passive cigare
Publikováno v:
The Journal of Infectious Diseases. 202:1685-1689
Individuals with self-healed tuberculosis from the preantibiotic era offer a unique insight into the natural history of and protective immunity to tuberculosis. In 27 such persons whose tuberculosis self-healed >50 years earlier, circulating Mycobact
Autor:
Sarah Hackforth, Hansa Varia, Mustafa Bakir, John A. Innes, Geoffrey Pasvol, Xiaoqing Liu, Kerry A. Millington, Ahmet Soysal, Rubamalar Gunatheesan, Ajit Lalvani, Davinder Dosanjh, Robert N. Davidson, Timothy S. C. Hinks
Publikováno v:
Infection and Immunity. 77:5486-5495
The majority of individuals infected withMycobacterium tuberculosisachieve lifelong immune containment of the bacillus. What constitutes this effective host immune response is poorly understood. We compared the frequencies of gamma interferon (IFN-γ
Autor:
Katie J. Ewer, Luca Richeldi, Monica Losi, Timothy S. C. Hinks, Ajit Lalvani, Sarah Gooding, Ruba Gunatheesan, Kerry A. Millington, Stefania Cerri, Oni Chowdhury, Jeremy McNally
Publikováno v:
The Journal of Infection
Università degli studi di Modena e Reggio Emilia-IRIS
Università degli studi di Modena e Reggio Emilia-IRIS
Summary New T cell-based blood tests for tuberculosis infection could improve diagnosis of tuberculosis but their clinical utility remains unknown. We describe the role of the ELISpot test in the diagnostic work-up of 13 patients presenting with susp
Autor:
Luca Richeldi, Barbara Maria Bergamini, Monica Losi, Ajit Lalvani, Kerry A. Millington, Leonardo M. Fabbri, Katie J. Ewer
Publikováno v:
Pediatrics. 119:e1-e5
Young children exposed to tuberculosis have a high risk of progression to severe tuberculosis disease, but diagnosis of recent infection is hindered by the poor sensitivity of the tuberculin skin test. Whether new blood tests can detect latent infect
Autor:
Katie J. Ewer, Kerry A. Millington, Gerry Bryant, Ajit Lalvani, Lydia Alvarez, Jonathan J Deeks
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 174:831-839
The kinetics of Mycobacterium tuberculosis-specific Th1-type T-cell responses after M. tuberculosis infection are likely to be important in determining clinical outcome.To investigate the kinetics of T-cell responses, in the context of a point-source
Autor:
Ajit Lalvani, Kerry A. Millington
Publikováno v:
The Journal of Infectious Diseases. 197:941-943
The cytokine interferon-y (IFN-y) plays a pivotal role in protective immunity against intracellular pathogens. Specifically, in Mycobacterium tuberculosis (MTB) infection, IFN-y is an important mediator of macrophage activation [ 1 ] . Mice deficient