Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kerrie Thackray"'
Autor:
Kerrie Thackray, Felicity Kaplan
Publikováno v:
Endocrine Abstracts.
Publikováno v:
Endocrine Abstracts.
Autor:
Julie Harris, Alexandra Kinzer, David B. Savage, Robert K. Semple, Claire Adams, Rebecca J. Brown, Marc de Kerdanet, Mercedes Jimenez-Linan, Anna Stears, Stephen O'Rahilly, Isabel Huang-Doran, Kerrie Thackray, Phillip Gorden
Publikováno v:
The Journal of Clinical Endocrinology and Metabolism
Context Insulin resistance (IR) is associated with polycystic ovaries and hyperandrogenism, but underpinning mechanisms are poorly understood and therapeutic options are limited. Objective To characterize hyperandrogenemia and ovarian pathology in pr
Autor:
T. Adrian Carpenter, Alessandra Gambineri, David B. Savage, V. Irene Campi, Peter R. Murgatroyd, Graham J. Kemp, Anna Stears, Stephen O'Rahilly, Alison Sleigh, Nadia Schoenmakers, Kerrie Thackray, Sath Nag, Laura Watson, Soren Brage
Publikováno v:
The Journal of Clinical Endocrinology and Metabolism
Objective: Lipid accumulation in skeletal muscle and the liver is strongly implicated in the development of insulin resistance and type 2 diabetes, but the mechanisms underpinning fat accrual in these sites remain incompletely understood. Accumulatin
Autor:
David B. Savage, David Porter, Kerrie Thackray, Alessandra Vottero, Alison Sleigh, Graham J. Kemp, Mensud Hatunic, Christine P Burren, Philippa Raymond-Barker, Martin McIntyre, Catherine Mitchell, Stephen O'Rahilly, Robert K. Semple, Soren Brage, Peter R. Murgatroyd, Kevin M. Brindle, T. Adrian Carpenter
Publikováno v:
Journal of Clinical Investigation. 121:2457-2461
Mitochondrial dysfunction is associated with insulin resistance and type 2 diabetes. It has thus been suggested that primary and/or genetic abnormalities in mitochondrial function may lead to accumulation of toxic lipid species in muscle and elsewher