Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Kerrie L. McDonald"'
Autor:
Taeyoung Hwang, Dimitrios Mathios, Kerrie L. McDonald, Irene Daris, Sung-Hye Park, Peter C. Burger, Sojin Kim, Yun-Sik Dho, Hruban Carolyn, Chetan Bettegowda, Joo Heon Shin, Michael Lim, Chul-Kee Park
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-12 (2019)
Abstract The study of survival outliers of glioblastoma can provide important clues on gliomagenesis as well as on the ways to alter clinical course of this almost uniformly lethal cancer type. However, there has been little consensus on genetic and
Externí odkaz:
https://doaj.org/article/6b54e677e8cf472dbbb96b9facdc5ed2
Autor:
Jessica Buck, Patrick J. C. Dyer, Hilary Hii, Brooke Carline, Mani Kuchibhotla, Jacob Byrne, Meegan Howlett, Jacqueline Whitehouse, Martin A. Ebert, Kerrie L. McDonald, Nicholas G. Gottardo, Raelene Endersby
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Medulloblastoma is the most common malignant childhood brain tumor, and 5-year overall survival rates are as low as 40% depending on molecular subtype, with new therapies critically important. As radiotherapy and chemotherapy act through the inductio
Externí odkaz:
https://doaj.org/article/84c2daf88f7a475d8429aa6028e5b6ae
Autor:
Camila Ferreira de Souza, Thais S. Sabedot, Tathiane M. Malta, Lindsay Stetson, Olena Morozova, Artem Sokolov, Peter W. Laird, Maciej Wiznerowicz, Antonio Iavarone, James Snyder, Ana deCarvalho, Zachary Sanborn, Kerrie L. McDonald, William A. Friedman, Daniela Tirapelli, Laila Poisson, Tom Mikkelsen, Carlos G. Carlotti, Jr., Steven Kalkanis, Jean Zenklusen, Sofie R. Salama, Jill S. Barnholtz-Sloan, Houtan Noushmehr
Publikováno v:
Cell Reports, Vol 23, Iss 2, Pp 637-651 (2018)
Summary: Glioma diagnosis is based on histomorphology and grading; however, such classification does not have predictive clinical outcome after glioblastomas have developed. To date, no bona fide biomarkers that significantly translate into a surviva
Externí odkaz:
https://doaj.org/article/706cab09ad454b2da0b587fe71e18729
Publikováno v:
Cancers, Vol 13, Iss 21, p 5362 (2021)
Background: Identification of prognostic biomarkers in cancers is a crucial step to improve overall survival (OS). Although mutations in tumour protein 53 (TP53) is prevalent in astrocytoma, the prognostic effects of TP53 mutation are unclear. Method
Externí odkaz:
https://doaj.org/article/45f3e58e52dd470a99b0524811570245
Autor:
Guoqing Bao, Xiuying Wang, Ran Xu, Christina Loh, Oreoluwa Daniel Adeyinka, Dula Asheka Pieris, Svetlana Cherepanoff, Gary Gracie, Maggie Lee, Kerrie L. McDonald, Anna K. Nowak, Richard Banati, Michael E. Buckland, Manuel B. Graeber
Publikováno v:
Cancers, Vol 13, Iss 4, p 617 (2021)
We have developed a platform, termed PathoFusion, which is an integrated system for marking, training, and recognition of pathological features in whole-slide tissue sections. The platform uses a bifocal convolutional neural network (BCNN) which is d
Externí odkaz:
https://doaj.org/article/fcb1996efc964e56b8fb29599437ba5a
Isocitrate dehydrogenase 1 mutation subtypes at site 132 and their translational potential in glioma
Autor:
Victor M Lu, Kerrie L McDonald
Publikováno v:
CNS Oncology, Vol 7, Iss 1, Pp 41-50 (2018)
In recent years, de novo missense structural mutations in the IDH1 gene of arginine at site 132 (R132) have become a standard for diagnostication and prognostication in glioma management. As our clinical understanding of this mutation grows, so too d
Externí odkaz:
https://doaj.org/article/dcc3df9d4b824d0b829ae0f00443b039
Table S1. The surviving fractions of GBM cell lines after treatment with DCA as a single agent.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f00a0be848dc12af7ea55fb716f88e
https://doi.org/10.1158/1535-7163.22506744
https://doi.org/10.1158/1535-7163.22506744
Autor:
John E. Pimanda, Bryan W. Day, Kerrie L. McDonald, Ashwin Unnikrishnan, Han Shen, Govardhan Anande, Shruthi Subramanian, Zeenat Jahan, Toni Rose Jue, Kathleen S. Ensbey, Sylvia A. Chung, Brett W. Stringer, Julie A.I. Thoms, Anchit Khanna
Figure S1, related to Figure 1: Expression and correlation of CHK1 and CIP2A in multiple glioma cohorts. Figure S2, related to Figure 1: Overall survival and mRNA expression of PP2A subunits in glioma patients. Figure S3, related to Figure 1: Role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::797ba9f3cc2355aafc11bcb0f6c2b6c1
https://doi.org/10.1158/1541-7786.22515163.v1
https://doi.org/10.1158/1541-7786.22515163.v1
Because radiotherapy significantly increases median survival in patients with glioblastoma, the modulation of radiation resistance is of significant interest. High glycolytic states of tumor cells are known to correlate strongly with radioresistance;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82ebd8b0225f25b32132ef5f13707328
https://doi.org/10.1158/1535-7163.c.6538479.v1
https://doi.org/10.1158/1535-7163.c.6538479.v1
Autor:
Kerrie L. McDonald, Bruce G. Robinson, Charles Teo, Nicholas S. Little, Michael T. Biggs, Raymond J. Cook, Helen R. Wheeler, Jonathon F. Parkinson, Nathan R. Hall, Glenn Stone, Maree G. O'Sullivan, Marinella Messina, Sanaz Maleki, Cathy A. Payne
Supplementary Table S1 from Loss of prostaglandin D2 synthase: a key molecular event in the transition of a low-grade astrocytoma to an anaplastic astrocytoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2444e98b55202949378ead28d376eca1
https://doi.org/10.1158/1535-7163.22483427
https://doi.org/10.1158/1535-7163.22483427