Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kerrie E. McNally"'
Autor:
Kejia Wu, Hua Bai, Ya-Ting Chang, Rachel Redler, Kerrie E. McNally, William Sheffler, T. J. Brunette, Derrick R. Hicks, Tomos E. Morgan, Tim J. Stevens, Adam Broerman, Inna Goreshnik, Michelle DeWitt, Cameron M. Chow, Yihang Shen, Lance Stewart, Emmanuel Derivery, Daniel Adriano Silva, Gira Bhabha, Damian C. Ekiert, David Baker
Publikováno v:
Nature. 616:581-589
General approaches for designing sequence-specific peptide-binding proteins would have wide utility in proteomics and synthetic biology. However, designing peptide-binding proteins is challenging, as most peptides do not have defined structures in is
Autor:
Vicente José Planelles-Herrero, Mariya Genova, Alice Bittleston, Kerrie E. McNally, Gianluca Degliesposti, Maria M. Magiera, Carsten Janke, Emmanuel Derivery
Elongator is a tRNA-modifying complex that regulates the fidelity of protein translation. Recently, a moonlighting function of Elongator has been identified in regulating polarization of the microtubule cytoskeleton during asymmetric cell division. E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccd59a1365594b0a3076d86aa7f869fe
https://doi.org/10.1101/2023.05.10.540202
https://doi.org/10.1101/2023.05.10.540202
Autor:
Michael D. Healy, Kerrie E. McNally, Rebeka Butkovic, Molly Chilton, Kohji Kato, Joanna Sacharz, Calum McConville, Edmund R.R. Moody, Shrestha Shaw, Vicente J. Planelles-Herrero, Sathish K.N. Yadav, Jennifer Ross, Ufuk Borucu, Catherine S. Palmer, Kai-En Chen, Tristan I. Croll, Ryan J. Hall, Nikeisha J. Caruana, Rajesh Ghai, Thi H.D. Nguyen, Kate J. Heesom, Shinji Saitoh, Imre Berger, Christiane Schaffitzel, Tom A. Williams, David A. Stroud, Emmanuel Derivery, Brett M. Collins, Peter J. Cullen
SUMMARYThe Commander complex is required for endosomal recycling of diverse transmembrane cargos and is mutated in Ritscher-Schinzel syndrome. It comprises two subassemblies; Retriever composed of VPS35L, VPS26C and VPS29, and the CCC complex which c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d210a5342199c943249b9d1af8c0d6
https://doi.org/10.2139/ssrn.4330804
https://doi.org/10.2139/ssrn.4330804
Autor:
Kejia Wu, Hua Bai, Ya-Ting Chang, Rachel Redler, Kerrie E. McNally, William Sheffler, TJ Brunette, Derrick R. Hicks, Tomos E Morgan, Tim J Stevens, Adam Broerman, Inna Goreshnik, Michelle DeWitt, Cameron M. Chow, Yihang Shen, Lance Stewart, Emmanuel Derivery, Daniel Adriano Silva, Gira Bhabha, Damian Ekiert, David Baker
General approaches for designing sequence-specific peptide binding proteins would have wide utility in proteomics and synthetic biology. Although considerable progress has been made in designing proteins which bind to other proteins, the general pept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a7fff23e15bdae13920e1136bfa6c20
https://doi.org/10.1101/2022.11.14.514089
https://doi.org/10.1101/2022.11.14.514089
Autor:
Michael D. Healy, Kerrie E. McNally, Rebeka Butkovič, Molly Chilton, Kohji Kato, Joanna Sacharz, Calum McConville, Edmund R.R. Moody, Shrestha Shaw, Vicente J. Planelles-Herrero, Sathish K.N. Yadav, Jennifer Ross, Ufuk Borucu, Catherine S. Palmer, Kai-En Chen, Tristan I. Croll, Ryan J. Hall, Nikeisha J. Caruana, Rajesh Ghai, Thi H.D. Nguyen, Kate J. Heesom, Shinji Saitoh, Imre Berger, Christiane Schaffitzel, Tom A. Williams, David A. Stroud, Emmanuel Derivery, Brett M. Collins, Peter J. Cullen
Publikováno v:
Cell. 186:2219-2237.e29
Autor:
Graham J Britton, Rachel Ambler, Danielle J Clark, Elaine V Hill, Helen M Tunbridge, Kerrie E McNally, Bronwen R Burton, Philomena Butterweck, Catherine Sabatos-Peyton, Lea A Hampton-O’Neil, Paul Verkade, Christoph Wülfing, David Cameron Wraith
Publikováno v:
eLife, Vol 6 (2017)
Notch is a critical regulator of T cell differentiation and is activated through proteolytic cleavage in response to ligand engagement. Using murine myelin-reactive CD4 T cells, we demonstrate that proximal T cell signaling modulates Notch activation
Externí odkaz:
https://doaj.org/article/75afcfe3d41645f7a11ec23c03da7a47
Autor:
Michael D. Healy, Joanna Sacharz, Kerrie E. McNally, Calum McConville, Vikas A. Tillu, Ryan J. Hall, Molly Chilton, Peter J. Cullen, Mehdi Mobli, Rajesh Ghai, David A. Stroud, Brett M. Collins
Publikováno v:
Structure. 30:1590-1602.e6
The sorting nexin SNX17 controls endosomal recycling of transmembrane cargo proteins including integrins, the amyloid precursor protein, and lipoprotein receptors. This requires association with the Commander trafficking complex and depends on the C
Autor:
David A. Stroud, Rajesh Ghai, Michael D. Healy, Calum McConville, Molly Chilton, Ryan J. Hall, Joanna Sacharz, Brett M. Collins, Mehdi Mobli, Peter J. Cullen, Kerrie E. McNally
The sorting nexin SNX17 controls endosome-to-cell surface recycling of diverse transmembrane cargo proteins including integrins, the amyloid precursor protein and lipoprotein receptors. This requires association with the multi-subunit Commander traff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e13ee45c517c3e54b7f048b8a1f4847
https://doi.org/10.1101/2021.07.29.454387
https://doi.org/10.1101/2021.07.29.454387
Autor:
Joanna Sacharz, Ryan J. Hall, Mehdi Mobli, Brett M. Collins, Rajesh Ghai, Peter J. Cullen, Michael D. Healy, Calum McConville, David A. Stroud, Molly Chilton, Kerrie E. McNally
Publikováno v:
SSRN Electronic Journal.
The sorting nexin SNX17 controls endosome-to-cell surface recycling of diverse transmembrane cargo proteins including integrins, the amyloid precursor protein and lipoprotein receptors. This requires association with the multi-subunit Commander traff
Autor:
Lindsey L. Morris, Lawrence Banks, David Pim, Paul F. Langton, Amika Singla, Neil D. Pearson, Rebecca A. Faulkner, Kerrie E. McNally, Ezra Burstein, Chris M. Danson, Richard B. Sessions, Matthew Gallon, Rajesh Ghai, Brittany L. Overlee, Brett M. Collins, Heike Nägele, Imre Berger, Daniel D. Billadeau, Peter J. Cullen, Kate J. Heesom, Florian Steinberg
Publikováno v:
McNally, K E, Faulkner, R, Steinberg, F, Gallon, M, Ghai, R, Pim, D, Langton, P, Pearson, N, Danson, C M, Nägele, H, Morris, L L, Singla, A, Overlee, B L, Heesom, K J, Sessions, R, Banks, L, Collins, B M, Berger, I, Billadeau, D D, Burstein, E & Cullen, P J 2017, ' Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling ', Nature Cell Biology, vol. 19, no. 10, pp. 1214–1225 . https://doi.org/10.1038/ncb3610
Following endocytosis into the endosomal network, integral membrane proteins undergo sorting for lysosomal degradation or are retrieved and recycled back to the cell surface. Here we describe the discovery of an ancient and conserved multiprotein com