Výsledky vyhledávání - "Kerrie A Basclain"

Coincident increase in periportal expression of iron proteins in the iron-loaded rat liver

Autor: Kerrie A Basclain, Gary P. Jeffrey

Publikováno v: Journal of Gastroenterology and Hepatology. 14:659-668

Background: The liver is the major iron storage organ in the body and, as a result, total body iron stores closely regulate hepatocyte iron uptake, storage and release. Transferrin, transferrin receptor and ferritin facilitate these processes. Method

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b3f31550431bc8c8499e7aba2d8a239
https://doi.org/10.1046/j.1440-1746.1999.01932.x

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Expression and localization of the inducible isoform of nitric oxide synthase in nasal polyp epithelium

Autor: D.J. Peroni, Philip J. Thompson, Kerrie A Basclain, M.J. Garlepp, D.N. Watkins, P.H. Fisher, R.H. Lewis

Publikováno v: Clinical & Experimental Allergy. 28:211-219

Background The pathogenesis of nasal polyp disease is poorly understood. Recent evidence has suggested that nitric oxide (NO), an endogenous soluble gas vasodilator and inflammatory mediator, may be synthesised within the nasal cavity. Three nitric o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::405515dabd09e6a5921e100a03598558
https://doi.org/10.1046/j.1365-2222.1998.00215.x

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Expression and activity of nitric oxide synthases in human airway epithelium

Autor: Kerrie A Basclain, Philip J. Thompson, D.N. Watkins, M.J. Garlepp, D.J. Peroni

Publikováno v: American Journal of Respiratory Cell and Molecular Biology. 16:629-639

Nitric oxide (NO) synthesized by airway epithelium may be important in the regulation of airway inflammation and reactivity. As such, the expression and localization of nitric oxide synthase (NOS) isoforms was assessed in human airway tissue obtained

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f892df2a3852f87e0dab8819a3eee2c4
https://doi.org/10.1165/ajrcmb.16.6.9191464

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Iron excretion in iron-overloaded rats following the change from an iron-loaded to an iron-deficient diet

Autor: Gary P. Jeffrey, Evan H. Morgan, Carla Thomas, Phillip S. Oates, Kerrie A Basclain

Publikováno v: Journal of gastroenterology and hepatology. 15(6)

Background: Iron stores in the body are thought to be regulated by a mechanism associated with the rate of iron absorption from the diet, with no significant role played by iron excretion. We report the existence of an iron excretory process that res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::790b0d783410af76eb70ee3303aeb832
https://pubmed.ncbi.nlm.nih.gov/10921422

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Alternate splicing produces a soluble form of the hereditary hemochromatosis protein HFE

Autor: Paul C. Adams, Gary Jeffrey, Kerrie A Basclain, Subrata Chakrabarti, Jan Hajek

Publikováno v: Blood cells, moleculesdiseases. 25(1)

HFE is a non-typical MHC class 1-type protein that is mutated in hereditary hemochromatosis. The purpose of this study was to identify possible splice variants of HFE mRNA and investigate the regulation of these isoforms in duodenum and liver of pati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a558d5f5dba8e1b7c2b98631b403a3f
https://pubmed.ncbi.nlm.nih.gov/10349514

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Cellular expression and regulation of iron transport and storage proteins in genetic haemochromatosis

Autor: Kerrie A Basclain, K. B. Shilkin, Geoffrey Withers, William Reed, Gary P. Jeffrey

Publikováno v: Journal of gastroenterology and hepatology. 13(6)

Genetic haemochromatosis is a common iron overload disorder of unknown aetiology. To characterize the defect of iron metabolism responsible for this disease, this study localized and semi-quantified the mRNA and protein expression of transferrin, tra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49cce8459593d27f83784f743429042d
https://pubmed.ncbi.nlm.nih.gov/9715407

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Molecular regulation of transferrin receptor and ferritin expression in the rat gastrointestinal tract

Autor: Tracey L. Allen, Kerrie A Basclain, Gary P. Jeffrey

Publikováno v: Gastroenterology. 110(3)

BACKGROUND & AIMS: The role of the transferrin receptor and ferritin i n the regulation of intestinal dietary iron uptake and excretion is unknown. This study aimed to determine the regulation of transferrin receptor and ferritin messenger RNA (mRNA)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ececd84785eb96a0eef35330bca93ebd
https://pubmed.ncbi.nlm.nih.gov/8608889

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Akademický článek

Iron excretion in iron-overloaded rats following the change from an iron-loaded to an iron-deficient diet.

Autor: Oates, P, Oates, Phillip S, Jeffrey, Gary P, Basclain, Kerrie A, Thomas, Carla, Morgan, Evan H

Publikováno v: Journal of Gastroenterology & Hepatology; Jun2000, Vol. 15 Issue 6, p665-674, 10p, 2 Black and White Photographs, 2 Charts, 5 Graphs

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Akademický článek

Coincident increase in periportal expression of iron proteins in the iron-loaded rat liver.

Autor: Basclain, Kerrie, Jeffrey, Gary

Publikováno v: Journal of Gastroenterology & Hepatology; Jul99, Vol. 14 Issue 7, p659-668, 10p, 24 Black and White Photographs, 1 Diagram, 1 Chart, 1 Graph

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