Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Kerri S, Warren"'
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 281:H1711-H1719
Genetic studies in zebrafish have focused on embryonic mutations, but many physiological mechanisms continue to mature after embryogenesis. We report here that zebrafish homozygous for the mutation slow mo can be raised to adulthood. In the embryo, t
Autor:
Kerri S. Warren, Donald Jackson, Jau-Nian Chen, Allan M. Goldstein, Per Lindahl, George N. Serbedzija, Mark C. Fishman, Frauke van Bebber, John D. Mably, Fabrizio C. Serluca, Alan N. Mayer, Pascal Haffter, Sarah J. Childs
Publikováno v:
Comparative and Functional Genomics
Comparative and functional genomics, vol 2, iss 2
Comparative and Functional Genomics, Vol 2, Iss 2, Pp 60-68 (2001)
Comparative and functional genomics, vol 2, iss 2
Comparative and Functional Genomics, Vol 2, Iss 2, Pp 60-68 (2001)
All internal organs are asymmetric along the left–right axis. Here we report a genetic screen to discover mutations which perturb organ laterality. Our particular focus is upon whether, and how, organs are linked to each other as they achieve their
Publikováno v:
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 355:939-944
The vertebrate heart differs from chordate ancestors both structurally and functionally. Genetic units of form, termed ‘modules’, are identifiable by mutation, both in zebrafish and mouse, and correspond to features recently acquired in evolution
Publikováno v:
Proceedings of the National Academy of Sciences. 94:4554-4559
At a cellular level, cardiac pacemaking, which sets the rate and rhythm of the heartbeat, is produced by the slow membrane depolarization that occurs between action potentials. Several ionic currents could account for this pacemaker potential, but th
Autor:
Jeffrey McDermott, Jenny Li-Chun Lin, Kerri S. Warren, Jim J.-C. Lin, David R. Soll, Damon C. Shutt
Publikováno v:
Cell Motility and the Cytoskeleton. 34:215-229
Previous studies have demonstrated that overexpression of the carboxyl-terminal fragment, CaD39, of human fibroblast caldesmon in Chinese hamster ovary cells protected endogenous tropomyosin from turnover and stabilized actin microfilament bundles [W
Publikováno v:
The Journal of Cell Biology
Human fibroblasts generate at least eight tropomyosin (TM) isoforms (hTM1, hTM2, hTM3, hTM4, hTM5, hTM5a, hTM5b, and hTMsm alpha) from four distinct genes, and we have previously demonstrated that bacterially produced chimera hTM5/3 exhibits an unusu
Publikováno v:
Advances in experimental medicine and biology. 644
Over the past two decades, extensive molecular studies have identified multiple tropomyosin isoforms existing in all mammalian cells and tissues. In humans, tropomyosins are encoded by TPM1 (alpha-Tm, 15q22.1), TPM2 (beta-Tm, 9p13.2-p13.1), TPM3 (gam
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9780387857657
Over the past two decades, extensive molecular studies have identified multiple tropomyosin isoforms existing in all mammalian cells and tissues. In humans, tropomyosins are encoded by TPM1 (α-Tm, 15q22.1), TPM2 (β-Tm, 9p13.2–p13.1), TPM3 (γ-Tm,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a40a1055381b8ca71f6db265c922c21b
https://doi.org/10.1007/978-0-387-85766-4_16
https://doi.org/10.1007/978-0-387-85766-4_16
Autor:
Kerri S. Warren, Mark C. Fishman
Publikováno v:
The American journal of physiology. 275(1)
Large-scale mutagenesis screens have proved essential in the search for genes that are important to development in the fly, worm, and yeast. Here we present the power of large-scale screening in a vertebrate, the zebrafish Danio rerio, and propose th
Vertebrate nonmuscle cells, such as human and rat fibroblasts,express multiple isoforms of tropomyosin, which are generated from four different genes and a combination of alternative promoter activities and alternative splicing. The amino acid variab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14da01f694f0445a4ceee84e2b094049
https://doi.org/10.1016/s0074-7696(08)61619-8
https://doi.org/10.1016/s0074-7696(08)61619-8